The Fed Metabolism

Question	Answer
Liver- Glucose Transporter (And why)	GLUT2- So that glucose only enters when glucose is high (say after a meal) and glycogen must be made
Liver- Glucose	Made into glycogen/pyruvate
Liver- Pyruvate	Made into F.A's through Acetyl CoA
Liver- Acetyl CoA	Used to make TAGs or enters the TCA cycle
Liver- Glycerol	Used to make TAG's
Liver- TAG's	Leave the liver as VLDLs to provide sustenance for other cells
Muscle- Glucose Transporter	4, so glucose is available at all time
Muscle- Glucose	Used to make glycogen, or converted to pyruvate
Muscle- Pyruvate	Used for the TCA cycle (nothing else)
Muscle- Amino Acids	Used to make protein (to build muscle) or Acetyl CoA for the TCA cycle
Muscle- LPL	For the breakdown of VLDLs/Chylomicrons for Acetyl CoA
Adipose Tissue- Glucose Receptor	4- affected most by insulin, bc fat generation depends on state of body
Adipose Tissue- Glucose	Made into Glycerol-3-phosphate for fat generation, or into pyruvate
Adipose Tissue- Pyruvate	For acetyl CoA, for TAG generation and the TCA cycle
Adipose Tissue- LPL	Grabs F.As from VLDLs/Chylomicrons to make TAGs
Brain Tissue- Glucose Transporters	1 & 3- most sensitive to glucose since the brain can't use anything else
Brain Tissue- Glucose	Acetyl CoA for the TCA cycle. No exceptions that they've taught us

Resource summary

	Created by gina_evans0312 over 10 years ago