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Description
Flashcards by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312
almost 11 years ago
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| Question | Answer |
| N. gonorrheae- Gram Staining | Gram +ve cocci pairs |
| N. gonorrheae- Culture media | Chocolate agar- needs CO2 |
| N. gonorrheae- Oxidase Test | +ve |
| N. gonorrheae- Infection Characteristics | Many pus cells, as bacteria can live inside neutraphils |
| N. gonorrheae- Infection Type | Urethritis |
| N. meningiditis- Gram Staining | Gram +ve cocci pairs (everything's the same as N. gonorrheae) |
| N. meningiditis- Initial Infection Location | Nasopharynx, allows it to reach the brain and blood |
| N. meningiditis- Infection Type | Meningitis, septicemia |
| Miningococcal Septicemia- Infection Characteristics | A non-blanching rash |
| Miningococcal Septicemia- Source | Humans (only reservoir) |
| Miningococcal Septicemia- Transmission | Close contact |
| Miningococcal Septicemia- Host Immunity | Usually requires an immunocompromised host |
| Miningococcal Septicemia- Movement through Body (Normal) | Nasopharynx-blood-CSF |
| Miningococcal Septicemia- Movement Through Body (Possible) | Through Cribiform Plate in room of mouth, directly through olfactory nerves |
| Miningococcal Virulence Factors- Pilus | Enable it to penetrate through mucus |
| Miningococcal Virulence Factors Outer membrane proteins- | Target specific epithelial receptors allow easy binding to cells |
| Miningococcal Virulence Factors- Capsule | Evade immune responses - i.e. hides c3b compliment proteins during opsonisation |
| Miningococcal Virulence Factors- Sialic Acid | Found in host cells, allows evasion of immune response |
| Miningococcal Virulence Factors- IgA Protease | Breaks down binding Igs |
| Miningococcal Virulence Factors- Compliment Inhibitory Factor | Kinda obvious... |
| Miningococcal Virulence Factors- Neutrophils | Can actively divide inside them, by resisting ROS attacks and using them as a hiding place |
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