16214680
Description
Mind Map by ahmed alhabshi, updated more than 1 year ago
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- anatomy of the Adrenal gland
- Histology of adrenal gland
- secretes
- Glucocorticoids - Cortisol
- Produced in response to ACTH
- physiology of corticosteroids
- excess cortisol leads to
- Cushing Syndrome
- exogenous or endogenous
- Exogenous (Cushing’s syndrome):
- Organ Transplant
- Chemotherapy (Long term use of steroids).
- Autoimmune diseases.
- Asthma.
- Allergies.
- Chronic inflammatory diseases.
- Hypertension.
- Type II diabetes.
- Organ Transplant
- Exogenous (Cushing’s syndrome):
- Pathophysiology
- When stimulated by ACTH, the adrenal gland secretes cortisol and other
steroid hormones. ACTH is produced by the pituitary gland and released
into the petrosal venous sinuses in response to stimulation by
corticotropin-releasing hormone (CRH) from the hypothalamus
- When stimulated by ACTH, the adrenal gland secretes cortisol and other
steroid hormones. ACTH is produced by the pituitary gland and released
into the petrosal venous sinuses in response to stimulation by
corticotropin-releasing hormone (CRH) from the hypothalamus
- Risk factors
- Female
- 25-40 years
old
- Female
- exogenous or endogenous
- Cushing Syndrome
- physiology of corticosteroids
- Produced in response to ACTH
- Mineralocorticoids - Aldosterone
- Androgens
- Stress hormones - Epinephrine & Norepinephrine
- Glucocorticoids - Cortisol
- secretes
- Histology of adrenal gland
- Nadia, round face, bruised, depressed, obese,
- other signs and symptoms
- Dysmenorrhea or Amenorrhea
- Muscle weakness
- Severe fatigue
- Loss of emotional control
- Cognitive difficulties
- Cognitive difficulties
- Loss of emotional control
- Severe fatigue
- New or worsened high blood pressure
- Headache
- Bone loss, leading to fractures over time
- Hirsutism
- Hirsutism
- In children, impaired growth
- Dysmenorrhea or Amenorrhea
- diagnosed with cushing's disease
- treated with hormone replacement therapy & surgery
- Management
- hormone replacement
- corticosteroids
- Clnical use
- Immunosuppressive Therapy
- Raised intracranial pressure
- skin diseases
- Acceleration of fetal lung maturation
- Immunosuppressive Therapy
- Adverse
Effects
- imuunosuppressing
- reduce bone growth
- peptic ulcers
- peptic ulcers
- weakness and
infections
- imuunosuppressing
- Clnical use
- corticosteroids
- Surgery
- transphenoidal,
removes tumor in
sella tucica.
- Complications
- Sinus headache and
congestion for up to a
week or 2 after
surgery.
- Brain damage, a
stroke, or blindness if
a nerve or artery is
damaged
- Diabetes insipidus
- panhypopituitarism
- Sinus headache and
congestion for up to a
week or 2 after
surgery.
- transphenoidal,
removes tumor in
sella tucica.
- hormone replacement
- Management
- treated with hormone replacement therapy & surgery
- other signs and symptoms
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