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2425978
Stomach
Description
Mind Map on Stomach, created by chaitanyashah.dr on 02/04/2015.
No tags specified
stomach pathology
stomcah histology
pathology
medicine
usmle
Mind Map by
chaitanyashah.dr
, updated more than 1 year ago
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Created by
chaitanyashah.dr
over 9 years ago
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Resource summary
Stomach
Gastroschisis
Congenital malformation of abd wall exposing abd contents
Omphalocele
Persistent herniation of the bowel into the umblical cord
due to failure of the herniated intestines to return
Contents are covered by peritoneum
Abd contents in a bubble
Pyloric stenosis
Congenital stenosis of pyloric sphincter
Seen more commonly in males
Clinical features
Commonly presented after 2 weeks of birth
Projectile nonbilous vommiting
Visible peristalisis
Olive like mass in abdomen
Treatment is Myotomy
Acute Gastritis
Acidic Damage to stomach mucosa
Imbalance between mucosal defences and acidic imbalance
Mucin layer by foveolar cells
Bicarbonate secretion by surface epithelium
Normal blood supply which takes up leaked acid
Risk Factors
Severe Burn (curling ulcer)
NSAIDs
Alcohol
Chemotherapy
Increased ICP
Increasead stimulation of vagus nerve > acid production
Shock (multiple stress ulcers)
Chronic Gastritis
Chronic Inflammation of Gastric mucosa
Two types
Chronic Autoimmune
Autoimmune destruction of gastric parietal cells
Parietal cells are located in body and fundus
Pathogenesis mediated by T Cells (Type IV)
Diagnosis: Antibodies against Parietal Cells and IF
Clinical feaures
Atrophy of mucosa
intestinal metaplasia
Achlorhydria
Megaloblastic anemia due to lack if IF
risk of gastric adenocarcinoma
Chronic H.pylori
Most common form of Gastritis
H.pylori secretes ureases and proteases
Antrum is most common site
Clinical Features
MALT
Abdominal Pain
Gastric Adenocarcinoma risks
Triple Therapy
Resolves Gastric ulcer
Negative urea breath & lack of stool antigen to confirm eradication of H.pylori
Reverses intestinal metaplasia
Peptic Ulcer Disease
Solitary mucosal ulcer in duodenum (90%) or in gastric mucosa (10%)
Two types
Duodenal
always due to H.pylori rarely due to ZE
epigastric pain improving with meals
Hypertrophy of Brunner glands on Endo
Rupture of Anterior ulcer- Gastroduodenal Artery bleeding
Posterior ulcer Rupture - Acute pancreatitis
Never Malignant
Gastric
H. Pylori (75%
NSAID & bile reflux
Located usually on the antrum
Pain worsens after meal
Rupture leads to bleed from Left epigastric A
May turn into malignant
Large irregular with heaped up margins
Benign are generally small (<3cm)
Punched out margins with radiating folds of mucosa
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