Splenic Disorders

Splenomegaly
1. Classify by:
  1. Nature of the Enlargement
    1. Uniform or Nodular
    2. The consistency of the tissue
      1. Wet/Blood or Firm
2. Uniform Enlargement
  1. Wet Consistency
    1. Lots of blood on cut section
    2. Congestion
      1. Ex. Portal Hypertension
    3. Barbituate Euthanasia
    4. Torsion
      1. Gastric Dilation & Torsion (Takes spleen w/ it)
    5. Anthrax
  2. Firm Consistency
    1. Chronic Stimulation (Anaemia, Infectious Disease)
      1. Diffuse Neoplasia
        Extramedullary Hematopoesis
3. Nodular
  1. Wet Consistency
    1. Heamatoma
      1. Neoplasia
        Especially Haemangioma/ haemangiosarcoma
        Haemangioma
        Haemangiosarcoma
        Primary Sites (Canine):
        Spleen
        RT Atrium
        Liver (can be 1st & 2ndary site)
        Skin
      2. Common, usually singular
  2. Firm Consistency
    1. Nodular Hyperplasia
      1. Non vascular(Mesenchymal) neoplsia/ metastasis
        Inflammation/Abscesses
        Ex. Rhodococcus equi, Arcanobacterium pyogenes, Strep equi, Bovine traumatic reticuloperitonitis
        Fibrosarcoma
        Fibrocytes
        Leimyosarcoma
        Smooth muscle cells
      2. Benign Nodular Hyperplasia is very common in old dogs
  3. Metastases to the Spleen
    1. Ex. Malignant Melanoma
Atrophy (Ageing/Wasting)
Contraction ex. Shock
Splenic Rupture
1. Splattered spleen syndrome
Siderofibrotic plaques/gamma-gandy bodies
Haemosiderin deposits
Infarcts
1. In peripheral (subcapsular) zones most prone
2. Where spleen is distended w/ blood, more prone to infarction

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Splenic Disorders

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	Created by melian.yates about 11 years ago