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44671
T-LYMPHOCYTES
Description
Bio Med and Pathology Mind Map on T-LYMPHOCYTES, created by aahughes on 12/04/2013.
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bio med and pathology
bio med and pathology
Mind Map by
aahughes
, updated more than 1 year ago
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Created by
aahughes
over 11 years ago
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Resource summary
T-LYMPHOCYTES
CELL MEDIATED RESPONSE
DO NOT produce antibodies
Directly kill pathogens
T-CELLS
PLURIPOTENT MARROW CELL
MATURE IN THE THYMUS GLAND
HELPER, MEMORY, KILLER, SUPPRESSOR
T-HELPER CELL
Communication link
Recognise the non self antigen that the macrophage presents
stimulate B-CELLS to produce plasma cells
B-CELLS cannot do this without T-HELPER CELLS
EFFECTOR CELLS
CYTOTOXIC KILLERS
Attach body cells which have been affected with viruses, bacteria and fungi
Kill the cell by recognition of the VIRAL PROTEIN COAT
Secrete PERFORIN PROTEIN which can perforate the cell membrane (LYSIS)
EFFECTOR AND MEMORY CELLS
Once activated they divide rapidly - POLYCONAL EXPANSION
T-SUPPRESSOR CELLS
REGULATE the action of lymphocytes -
Prevent the system from over reacting to stimuli
T-KILLER CELLS
Activated in the thymus
Sensitised when they encounter an antigen
Further development goes on in lymphatic tissues
T-CELLS emerge with different functions emerge
CYTOKINES
Act as a signal between cells
Primary role- immunoregulaton
COMPLEMENT
Assist antibodies to neutralise antigen
When antibodies and complement attack antigen - IMMUNE COMPLEX
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