46694
Descrição
FlashCards por Mark Arsenal, atualizado more than 1 year ago
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Criado por Mark Arsenal
mais de 11 anos atrás
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| Questão | Responda |
| What are the precursors of Gluconeogenesis? | Lactate- Generated in the muscles, it travels to the liver where it is broken down into Pyruvate then goes through Gluconeogenesis to form Glucose. Amino Acid Breakdown- form gluconeogenic intermediates which thus upregulate Gluconeogenesis. Glycerol- From Beta-oxidation, can be converted to form Gluconeogenesis intermediate which can work up to form Glucose. TCA Intermediates- Stimulate Gluconeogenesis through conversion to oxaloacetate (builds up-which stimulates) |
| What do we input and output in Gluconeogenesis? | We input 2 pyruvate+4ATP+2GTP+NADH. We Output Glucose+4ADP+2GDP+6Pi |
| Where are the only 2 locations that Gluconeogenesis can occur? | Liver and the Kidney. |
| What do we breakdown and form in Gluconeogenesis? | Pyruvate to Glucose (Opposite to Glycolysis) |
| Where does Gluconeogenesis take place? | Liver |
| What Important Organ is the prime user of Glucose as fuel? | Brain |
| How are Gluconeogenesis and Glycolysis linked? | Glycolysis breaks down Glucose to Pyruvate. Gluconeogenesis forms Glucose from Pyruvate. The 2 pathways are reciprocal, when 1 pathway is active the other is inhibited. |
| The pathway and Intermediates in Gluconeogenesis are the same as in Glycolysis (Just other way round). However Pyruvate is broken down to Oxaloacetate before becoming Phosphoenolopyruvate. | Gluconeogenesis Specific Enzymes- Pyruvate Carboxylase, Phosphoenolpyruvate Carboxykinase, Fructose 1,6 Biphosphatase, Glucose 6 Phosphatase. "Pathway Produces Fresh Glucose" |
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