Neissaria Family

Descrição

Medical Microbiology (Meningitis) FlashCards sobre Neissaria Family, criado por gina_evans0312 em 13-03-2014.
gina_evans0312
FlashCards por gina_evans0312, atualizado more than 1 year ago
gina_evans0312
Criado por gina_evans0312 mais de 10 anos atrás
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Resumo de Recurso

Questão Responda
N. gonorrheae- Gram Staining Gram +ve cocci pairs
N. gonorrheae- Culture media Chocolate agar- needs CO2
N. gonorrheae- Oxidase Test +ve
N. gonorrheae- Infection Characteristics Many pus cells, as bacteria can live inside neutraphils
N. gonorrheae- Infection Type Urethritis
N. meningiditis- Gram Staining Gram +ve cocci pairs (everything's the same as N. gonorrheae)
N. meningiditis- Initial Infection Location Nasopharynx, allows it to reach the brain and blood
N. meningiditis- Infection Type Meningitis, septicemia
Miningococcal Septicemia- Infection Characteristics A non-blanching rash
Miningococcal Septicemia- Source Humans (only reservoir)
Miningococcal Septicemia- Transmission Close contact
Miningococcal Septicemia- Host Immunity Usually requires an immunocompromised host
Miningococcal Septicemia- Movement through Body (Normal) Nasopharynx-blood-CSF
Miningococcal Septicemia- Movement Through Body (Possible) Through Cribiform Plate in room of mouth, directly through olfactory nerves
Miningococcal Virulence Factors- Pilus Enable it to penetrate through mucus
Miningococcal Virulence Factors Outer membrane proteins- Target specific epithelial receptors allow easy binding to cells
Miningococcal Virulence Factors- Capsule Evade immune responses - i.e. hides c3b compliment proteins during opsonisation
Miningococcal Virulence Factors- Sialic Acid Found in host cells, allows evasion of immune response
Miningococcal Virulence Factors- IgA Protease Breaks down binding Igs
Miningococcal Virulence Factors- Compliment Inhibitory Factor Kinda obvious...
Miningococcal Virulence Factors- Neutrophils Can actively divide inside them, by resisting ROS attacks and using them as a hiding place

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