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Criado por gina_evans0312
mais de 10 anos atrás
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Questão | Responda |
N. gonorrheae- Gram Staining | Gram +ve cocci pairs |
N. gonorrheae- Culture media | Chocolate agar- needs CO2 |
N. gonorrheae- Oxidase Test | +ve |
N. gonorrheae- Infection Characteristics | Many pus cells, as bacteria can live inside neutraphils |
N. gonorrheae- Infection Type | Urethritis |
N. meningiditis- Gram Staining | Gram +ve cocci pairs (everything's the same as N. gonorrheae) |
N. meningiditis- Initial Infection Location | Nasopharynx, allows it to reach the brain and blood |
N. meningiditis- Infection Type | Meningitis, septicemia |
Miningococcal Septicemia- Infection Characteristics | A non-blanching rash |
Miningococcal Septicemia- Source | Humans (only reservoir) |
Miningococcal Septicemia- Transmission | Close contact |
Miningococcal Septicemia- Host Immunity | Usually requires an immunocompromised host |
Miningococcal Septicemia- Movement through Body (Normal) | Nasopharynx-blood-CSF |
Miningococcal Septicemia- Movement Through Body (Possible) | Through Cribiform Plate in room of mouth, directly through olfactory nerves |
Miningococcal Virulence Factors- Pilus | Enable it to penetrate through mucus |
Miningococcal Virulence Factors Outer membrane proteins- | Target specific epithelial receptors allow easy binding to cells |
Miningococcal Virulence Factors- Capsule | Evade immune responses - i.e. hides c3b compliment proteins during opsonisation |
Miningococcal Virulence Factors- Sialic Acid | Found in host cells, allows evasion of immune response |
Miningococcal Virulence Factors- IgA Protease | Breaks down binding Igs |
Miningococcal Virulence Factors- Compliment Inhibitory Factor | Kinda obvious... |
Miningococcal Virulence Factors- Neutrophils | Can actively divide inside them, by resisting ROS attacks and using them as a hiding place |
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