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1771300
Adaptive Immunity (ONLY Lecture 15 Part 2)
Descrição
Adaptive Immunity will be in shades of red. Anything associated with innate immunity is in shades of blue. Lecture 16 is more in depth.
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lecture 15 pt 2
adaptive immunity
immunity
biol549
microbiology
microbiology 549
university
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GraceEChem
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Adaptive Immunity (ONLY Lecture 15 Part 2)
Humoral Immunity
"Antibody-mediated"
B-cell based
Cellular Immunity
"Cell-mediated"
T-cell based
Types
Naturally acquired active
Getting sick
B memory cells
Nat. acq. passive
Transfer (mother's milk)
Artificially acq. active
Vaccination
Art. acq. passive
Antibodies from one host intro to another
Antigens
Epitopes
Reaction sites on antigens for specific antibody or T cell receptor
Affinity
Binding strength at just ONE site
Avidity
Overall antigen-binding at ALL sites
Major Histocompatibility Complex (MHC)
Genes code for self/nonself
In humans "Human Leukocyte Antigen" (HLA)
Three Classes
CLASS I
All types
Important for organ transplant
CLASS II
Antigen-presenting cells
Important for T-cell communications
Macrophages
Dendritic cells
B cells
CLASS III
Secreted proteins
Nonself/self recognition
Class I and II Structures
Heterodimers of alpha & beta subunits
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