Heart Myocytes

Descrição

An example of a Direct- Effector Linked Pathway in Heart Myocytes. Note: The same neurotransmitter (acetylcholine) causes the opposite effect in skeletal muscle.
Sophie Barrett
Mapa Mental por Sophie Barrett, atualizado more than 1 year ago
Sophie Barrett
Criado por Sophie Barrett quase 11 anos atrás
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Resumo de Recurso

Heart Myocytes
  1. Stimulation from parasympathetic nervous system
    1. Acetylcholine acts on metabotropic, muscarinic receptors in the heart
      1. G-Protein is activated
        1. Effector protein is a K+ ion channel (stimulated to open)
          1. K+ ions flow out of the cell (down their concentration gradient)
            1. Increases negativity inside the cell (hyperpolarisation)
              1. Leads to decreased contraction

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