Copiar e Editar

HPV

Descrição

HPV test
Nicole Neumann
Mapa Mental por Nicole Neumann, atualizado more than 1 year ago
Nicole Neumann
Criado por Nicole Neumann aproximadamente 8 anos atrás
72
0
0

Resumo de Recurso

HPV
  1. 8k bp circular DNA
    1. ORFs
      1. Early onset genes
        1. E1
          1. replicates viral episomes
          2. E2
            1. replication + transcription
              1. regulates E6/E7
              2. E4
                1. Viral maturation + release
                2. E5
                  1. host cell proliferation
                    1. inhibits immune response?
                    2. E6
                      1. p53 inactivation
                        1. uncontrolled cell cycle
                      2. E7
                        1. pRB inactivation
                          1. uncontrolled cell cycle
                            1. E7+pRB => E2F
                              1. p16INK4
                                1. ICC biomarker
                        2. Late onset genes
                          1. L1
                            1. major capsid protein
                            2. L2
                              1. minor capsid protein
                        3. HPV types
                          1. high risk
                            1. HPV 16
                              1. dominates 57% total
                              2. HPV 18
                                1. 16% SCC
                                  1. dominates AdCA
                                2. low risk
                                  1. HPV 6 & 11
                                  2. host cell DNA integration
                                    1. persistent HPV infection
                                      1. mutations
                                      2. host cell DNA polymerase
                                    2. HPV vaccine
                                      1. Gardasil & Cervarix
                                        1. cross immunity
                                          1. virus like particles
                                            1. type specific
                                            2. L1 origin
                                            3. CIN
                                              1. CIN1
                                                1. 1/3 N/C
                                                  1. superficial/intermediate
                                                  2. CIN2
                                                    1. 2/3 N/C
                                                      1. intermediate/parabasal
                                                        1. medium clustering
                                                      2. CIN3
                                                        1. 2/3+ N/C
                                                          1. parabasal/basal
                                                            1. grapes
                                                              1. clustering

                                                          Quer criar seus próprios Mapas Mentais gratuitos com a GoConqr? Saiba mais.

                                                          Semelhante

                                                          IB Biology Topic 4 Genetics (SL)
                                                          R S
                                                          Epidemiology
                                                          Danielle Richardson
                                                          History of Medicine: Ancient Ideas
                                                          James McConnell
                                                          Epithelial tissue
                                                          Morgan Morgan
                                                          Laboratory Tools
                                                          Christopher Nikolo R. Magtoto
                                                          4. The Skeletal System - bones of the skull
                                                          t.whittingham
                                                          Neuro anatomy
                                                          James Murdoch
                                                          The Endocrine System
                                                          DrABC
                                                          Medical Terminology
                                                          khachoe_pema
                                                          Respiratory anatomy
                                                          James Murdoch
                                                          Diabetes - pathophysiology
                                                          Morgan Morgan
                                                          Explore a Biblioteca