10007789
Descrição
Quiz por Michael Jardine, atualizado more than 1 year ago
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Criado por Michael Jardine
aproximadamente 7 anos atrás
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Questão 1
Questão
The vast majority of cancers are:
Responda
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Monoclonal
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Polyclonal
Questão 2
Questão
Etymology.
The "Leuk-" part of leukaemia means what?
Responda
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Blood
-
White
-
Cancer
Questão 3
Questão
Etymology.
The "-aemia" part of leukaemia means what?
Responda
-
Blood
-
White
-
Cancer
Questão 4
Questão
Most cancers are derived from what type of cells?
Responda
-
Epithelial
-
Mesenchymal
Questão 5
Questão
Blood cell malignancies.
The most obvious difference between Leukaemia and Lymphoma is what?
Responda
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Leukaemia is mainly in circulation. Lymphoma is mainly in lymph nodes (or spleen).
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Leukaemia is mainly in lymph nodes (or spleen). Lymphoma is mainly in circulation.
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No noticeable differences.
Questão 6
Questão
Roughly what proportion of the cells in your body are blood cells?
Responda
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1 / 2
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1 / 4
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1 / 8
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1 / 16
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1 / 32
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1 / 64
Questão 7
Questão
What is the etymology of Macrophages?
(which are a subcategory of Leukocytes)
Responda
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Macro- = "Big" -phage = "Eater"
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Macro- = "Little" -phage = "Eater"
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Macro- = "Big" -phage = "Enzyme"
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Macro- = "Little" -phage = "Enzyme"
Questão 8
Questão
Etymology.
Blast cells. What does "Blast" mean in Greek?
Responda
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Bud
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Destroyer
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Eater
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Builder
Questão 9
Questão
What are the distinguishing features of Blast Cells?
(select all that apply)
Responda
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Haematopoietic progenitor cells
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Highly proliferative
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Large, transcriptionally active nucleus
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Survival and proliferation dependent on Growth Factor signalling
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Hepatopoietic progenitor cells
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Fully mature cells
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Normally found in large quantities in blood vessels
Questão 10
Questão
True or false?
Mature blood cells typically have more active nuclei than blasts.
Responda
- True
- False
Questão 11
Questão
True or false?
-blasts are the most likely cell type to become Leukaemic.
Responda
- True
- False
Questão 12
Questão
True or false?
-blasts are the least likely cell type to become Leukaemic.
Responda
- True
- False
Questão 13
Questão
True or false?
Mature blood cells typically have less active nuclei than blasts.
Responda
- True
- False
Questão 14
Questão
There are 4 types of Leukaemia. These include:
(select all that apply)
Responda
-
ALL - Acute Lymphoblastic Leukaemia
-
AML - Acute Myelogenous Leukaemia
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CLL - Chronic Lymphoblastic Leukaemia
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CML - Chronic Myelogenous Leukaemia
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ALL - Acute Lymphatic Leukaemia
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AML - Acute Myelodysplastic Leukaemia
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CLL - Chronic Lymphatic Leukaemia
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CML - Chronic Myelodysplastic Leukaemia
Questão 15
Questão
Acute Leukaemias arise from [blank_start]__________[blank_end] .
Chronic Leukaemias arise from [blank_start]__________[blank_end] .
Responda
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Stem Cells
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Committed Precursors
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Late Precursors and Mature Forms
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Stem Cells
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Committed Precursors
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Late Precursors and Mature Forms
Questão 16
Questão
There are 3 ways to donate marrow.
1 - Bone marrow transplant (becoming less common, though)
2 - PBSC
3 - Cord Blood (saved since birth)
PBSC stands for [blank_start]__________[blank_end] Blood Stem Cell
Responda
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Purified
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Peripheral
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Progenitor
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Please don't fuck this up
Questão 17
Questão
The Philadelphia chromosome (AKA Bcr-Abl) is a translocation between chromosomes 9 and 22 that results in a fusion protein called "BCR-ABL". What is the effect of this?
Responda
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Blocks myeloid differentiation in the progenitor stage
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Blocks myeloid differentiation in the haematopoietic stem cell stage
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Blocks lymphoid differentiation in the progenitor stage
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Blocks lymphoid differentiation in the haematopoietic stem cell stage
Questão 18
Questão
Bcr-Abl.
Bcr = Breakpoint Cluster Region protein
Abl = Abelson Murine Leukaemia viral oncogene homolog 1 (a non-receptor tyrosine kinase)
The fusion of the two results in what?
Responda
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Constitutive activation of the Abl kinase
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Inactivation of the Abl kinase
Questão 19
Questão
Lymphoma is a malignancy arising from which of the following?
Responda
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Progenitor B and T cells in the peripheral lymphoid tissues
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Progenitor B and T cells in the bloodstream
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Erythrocytes in the bloodstream
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Leukocytes in the bloodstream
Questão 20
Questão
Which of the following are symptoms of Leukaemia?
(select all that apply)
Responda
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Hyperviscosity syndrome
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Bruising
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Anaemia
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Arthritis
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Splenomegaly
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Abnormal blood cell profiles (more nucleated cells in the blood)
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Abnormal blood cell profiles (fewer nucleated cells in the blood
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