13496386
Questão 1
Questão
Use of succinylcholine to facilitate endotracheal intubation would be acceptable (“safe”) in which one of the following situations:
Responda
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80 y.o. female patient 2 days after 40% body surface area burn
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18 y. o. male one week after spinal cord transection injury
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12 y.o. with Duchene’s muscular dystrophy
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22 y. o. with evolving respiratory failure secondary to Guillian-Barre’
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27 y. o. female with myasthenia gravis
Questão 2
Questão
A patient taking which of the following drugs would most commonly be associated with resistance to (nondepolarizing) NMB drugs:
Responda
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Quinidine
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Phenytoin
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Cyclophosphamide
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Aminoglycosides
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Magnesium
Questão 3
Questão
The MOST important parameter that determines the speed of onset for NMB drugs is:
Responda
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Potency
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Lipophilicity
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Ionization
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Plasma clearance
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E. Receptor affinity
Questão 4
Questão
A characteristic common to current aminosteroid-based NMB drugs such as vecuronium or rocuronium is:
Responda
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Significant histamine release after a bolus injection
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Vagolysis producing tachycardia
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Hofmann elimination
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Deacetylation in the liver
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Production of laudanosine as the primary metabolite
Questão 5
Questão
Clinical data support that when the TOFR exceeds [blank_start]__[blank_end],
anesthesia providers have trouble assessing the presence
of fade
Responda
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0.4
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0.2
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0.7
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0.9
Questão 6
Questão
TOF count of 3 would equate to a twitch suppression of [blank_start]__[blank_end]%
Image:
Tofc (binary/octet-stream)
Responda
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55
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75
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85
-
90
Questão 7
Questão
Once the TOF ratio exceeds [blank_start]0.60[blank_end], fade to DBS generally cannot be detected subjectively
Image:
Dbs (binary/octet-stream)
Responda
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0.60
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0.40
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0.70
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0.85
Questão 8
Responda
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During partial depolarizing block, fade is not observed in response to tetanic stimulation
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Tetanic stimulation is not painful
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Muscular fatigue usually develop at a stimulation frequency of 50 Hz
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Fade is thought to be an effect of a depolarizing agent on the presynaptic nerve membrane
Questão 9
Responda
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The number of posttetanic count twitches is inversely related to time until the first regular TOF twitch returns
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Posttetanic count used when TOF or DBS is absent to estimate recovery time
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Posttetanic count uses tetany followed by TOF at frequency of 1 Hz
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The main use of posttetanic count is when profound neuromuscular block is not required
Questão 10
Questão
Correct statements about objective monitoring techniques include:
Responda
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Mechanomyography (MMG) measures isotonic contraction of peripheral muscles in response to nerve stimulation
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Acceleromyography (AMG) calculates the force of contraction of a muscle using a miniature piezoelectric transducer
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Electromyography (EMG) measures the electrical activity (compound muscle action potential) of a stimulated muscle
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Kinemyography (KMG) detects the acceleration of the thumb contraction in response to electrical stimulation of a nerve
Questão 11
Questão
All of the following are examples of Benzylisoquinolinium compounds consist of two quaternary ammonium groups joined by methyl groups EXCEPT:
Responda
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D-tubocurarine
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Atracurium
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Mivacurium
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Pancuronium
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Cisatracurium
Questão 12
Questão
Train-of-four (TOF) has all of the following characteristics, EXCEPT:
Image:
Tof (binary/octet-stream)
Responda
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TOF consists of four ST stimuli at a frequency of 4 Hz
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TOF does not require a “baseline” or “control” muscle response
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TOF “fade” is defined as a weaker fourth twitch than the first twitch
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TOF is delivered every 15-20 sec to prevent potentiation of subsequent responses
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TOF ratios >0.40 cannot be reliably detected subjectively (visually or tactilely)
Questão 13
Questão
Double burst stimulation (DBS) characteristics include all of the following, EXCEPT:
Image:
Dbs (binary/octet-stream)
Responda
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The two mini-tetanic bursts are separated by 0.5 sec
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DBS is delivered no more frequently than every 20 sec to prevent subsequent response potentiation
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In DBS, similar to TOF pattern, no control (“baseline”) muscle response is needed
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DBS ratios >0.60 cannot be reliably detected by subjective (tactile, visual) means
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In awakening patients, DBS is more painful than TOF, but less so than tetanic stimulation
Questão 14
Questão
Potential side-effects associated with the use of succinylcholine include all of the below, EXCEPT:
Responda
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Myalgia
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Tachycardia
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Anaphylaxis
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Hyperkalemia
Questão 15
Questão
Since sugammadex has no direct cholinergic properties, anesthesiologist do not require the ready availability of an anticholinergic like glycopyrrolate at the time of reversal.
Responda
- True
- False
Questão 16
Questão
When administering sugammadex through a peripheral IV, it is important to note that the drug has a physical incompatibility with all of the following drugs except:
Responda
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Verapamil
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Dexamethasone
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Ranitidine
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Odansetron
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