Questão 1
Questão
Brain tumours can be described as supratentorial and infratentorial based on their position in relation to the [blank_start]tentorium cerebelli[blank_end]
Questão 2
Questão
Which benign brain tumour of the pituitary gland is known to cause bitemporal hemianopia in children due to compression of the optic chiasm?
[blank_start]Craniopharyngioma[blank_end]
Questão 3
Questão
One of the main red flags for a brain tumour is a headache which is worse [blank_start]in the morning[blank_end]
Responda
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in the morning
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at night
-
during exercise
Questão 4
Questão
Whilst an intrinsic brain tumour affects the brain itself, an extrinsic brain tumour affects which of the following 2 structures?
Responda
-
Bone
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Meninges
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Spinal cord
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Nasal cavity
Questão 5
Questão
Cushing's triad is a series of signs/symptoms that are indicative of possible impending fatal herniation of the brain.
What are the constituents of this triad?
Questão 6
Questão
A patient showing signs of Cushing's triad should be immediately rushed to surgery for decompression. Which diuretic drug should be given in the meantime to ensure they don't pass away before reaching theatre?
[blank_start]Mannitol[blank_end]
Questão 7
Questão
A patient with a known brain tumour is unable to perform three separate motor functions in a row (such as rock, paper, scissors). It is likely their tumour is affecting which part of the brain?
Responda
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Frontal lobe
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Parietal lobe
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Temporal lobe
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Occipital lobe
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Insular lobe
Questão 8
Questão
Which are the main two imaging modalities for brain tumour diagnosis?
Responda
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CT
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MRI
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X-ray
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Ultrasound
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PET scan
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Angiogram
Questão 9
Questão
What is the most common type of brain tumour?
Responda
-
Metastases from cancer process elsewhere in the body
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Meningiomas
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Neuroepithelial tissue cancers
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Nerve sheath cell cancers
Questão 10
Questão
Neuroepithelial tissue brain tumours can arise from any of the following cell types, however which is the most common?
Responda
-
Astrocytes
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Oligodendrocytes
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Ependymal cells
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Neuronal cells
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Pineal cells
Questão 11
Questão
There are [blank_start]4[blank_end] WHO gradings of astrocytic tumours
Questão 12
Questão
The only truly benign astrocytoma is...
Responda
-
Grade I astrocytoma
-
Grade II astrocytoma
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Grade III astrocytoma
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Grade IV astrocytoma
Questão 13
Questão
Of all astrocytomas, which most commonly occur in children?
Responda
-
Grade I astrocytoma
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Grade II astrocytoma
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Grade III astrocytoma
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Grade IV astrocytoma
Questão 14
Questão
What is the most typical mode of treatment for a grade I astrocytoma?
Responda
-
Surgery
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Chemotherapy
-
Radiotherapy
Questão 15
Questão
Low grade astrocytomas are also known as
Responda
-
Grade I astrocytoma
-
Grade II astrocytoma
-
Grade III astrocytoma
-
Grade IV astrocytoma
Questão 16
Questão
What tends to be the main presentation of low grade astrocytomas?
Responda
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Headaches
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Seizures
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Diplopia
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Nausea+Vomiting
Questão 17
Questão
Low grade (Grade II) astrocytomas tend to affects people [blank_start]over[blank_end] 50
Questão 18
Questão
Low grade astrocytomas don't tend to differentiate into higher grade tumours (Grade III/IV) and therefore surgery is not recommended. Instead, serial imaging and potential chemo/radiotherapy is the mainstay of treatment.
Questão 19
Questão
Of the malignant astrocytomas, which is by far the most common?
Responda
-
Anaplastic Astrocytoma
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Glioblastoma Multiforme
Questão 20
Questão
Grade III Astrocytoma = [blank_start]Anaplastic Astrocytoma[blank_end]
Grade IV Astrocytoma = [blank_start]Glioblastoma Multiforme[blank_end]
Responda
-
Glioblastoma Multiforme
-
Anaplastic Astrocytoma
Questão 21
Questão
Which treatment has been proven to be most effective in treating brain tumours?
Questão 22
Questão
Meningiomas are the most common [blank_start]benign[blank_end] intracranial tumour. They arise from [blank_start]arachnoid[blank_end] cap cells in the meninges.
Responda
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arachnoid
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dura
-
pia
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benign
-
malignant
Questão 23
Questão
There are four aggressive meningiomas. What are they?
Questão 24
Questão
How are meningiomas typically managed?
Responda
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Surgery
-
Chemotherapy
-
Radiotherapy
Questão 25
Questão
A nerve sheath tumour originating in the myelin producing cells of the PNS is called a [blank_start]Schwannoma[blank_end]
Questão 26
Questão
A [blank_start]Vestibular Schwannoma[blank_end] is a tumour of the myelin forming cells of the 8th cranial nerve (vestibulocochlear nerve).
Questão 27
Questão
Vestibular Schwannomas tend to occur in patients with the condition [blank_start]Neurofibromatosis Type II[blank_end]
Questão 28
Questão
The most common CNS germ cell tumour is...
Responda
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Germinoma
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Teratoma
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Yolk sac Tumour
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Choriocarcinoma
Questão 29
Questão
There are 3 main tumour markers for germ cell tumours. Therefore, in a child with a midline brain tumour which 3 markers should be tested for?
Responda
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Alpha Fetoprotein (AFP)
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Human Choriogonadotrophin (bHCG)
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Placental Alkaline Phosphatase (pALP)
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Carcinoembryonic Antigen (CA)
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CA-125 Protein
Questão 30
Questão
Which type of drug can be used to shrink a Prolactinoma?
Questão 31
Questão
Name the dopamine receptor agonist used most frequently to shrink Prolactinomas
[blank_start]Cabergoline[blank_end]
Questão 32
Questão
The main therapy of choice for Acromegaly is the use of [blank_start]Somatostatin[blank_end] Analogues
Questão 33
Questão
Which of the following is a somatostatin analogue that can be used to treat acromegaly?
Responda
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Octreotide
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Lansoprazole
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Pramipexole
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Metyrapone
Questão 34
Questão
Tumour markers in germ cell tumours:
AFP present = [blank_start]Yolk Sac Tumour[blank_end]
Beta-hCG present = [blank_start]Choriocarcinoma[blank_end]
PLAP present = [blank_start]Germinoma[blank_end]
Responda
-
Germinoma
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Choriocarcinoma
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Yolk Sac Tumour