Questão 1
Questão
In terms of sleeping, there are both REM and non-REM cycles. What does 'REM' stand for?
[blank_start]Rapid eye movement[blank_end]
Questão 2
Questão
Which sleep type is most associated with dreaming?
Questão 3
Questão
The average adult spends 75% of their sleep in REM cycles and 25% in non-REM cycles
Questão 4
Questão
Which type of sleep is similar to wakefulness?
Questão 5
Questão
Which type of sleep is most important for protein synthesis, cell division and growth?
Questão 6
Questão
Melatonin is one of the main regulators of the circadian rhythm (along with cortisol level and low body temperature). Where is melatonin produced?
The [blank_start]Pineal Gland[blank_end]
Questão 7
Questão
Light entrains the circadian rhythm in humans:
Retinal [blank_start]ganglion[blank_end] cells project information to the [blank_start]suprachiasmatic[blank_end] nucleus in the hypothalamus to regulate sleep-wake cycles.
Responda
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ganglion
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bipolar
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horizontal
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amacrine
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Suprachiasmatic
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Preoptic
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Paraventricular
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Arcuate nucleus
Questão 8
Questão
What is considered the most important stage of sleep, allowing the cerebral hemispheres to effectively 'rest'?
Responda
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Light Non-REM sleep
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Deep Non-REM sleep
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REM sleep
Questão 9
Questão
A mid afternoon nap of 15 minutes is equivalent to 90 minutes overnight
Questão 10
Questão
Most studies suggest that 6-6.5 hours of sleep per night is acceptable for adults
Questão 11
Questão
[blank_start]Narcolepsy[blank_end] is a sleep disorder that is characterized by excessive sleepiness, sleep attacks, sleep paralysis, hallucinations and, for some, sudden loss of muscle control
Questão 12
Questão
The episodes of sudden muscle tone loss that is associated with 70% of narcolepsy patients is known as [blank_start]cataplexy[blank_end]
Questão 13
Questão
Cataplexy is a sudden loss of muscle tone in response to ...
Responda
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An emotion such as fear, surprise or joy
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A transient drop in blood pressure caused by activities such as standing up too quickly
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Hallucinations that tend to occur spontaneously throughout the day
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A sudden temperature drop
Questão 14
Questão
Narcolepsy with cataplexy has a known cause: a loss of cells in the brain that secrete a hormone responsible for wakefulness called ...
Responda
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Hypocretin
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Hippocretin
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Melatonin
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Hypotonin
Questão 15
Questão
Investigations for Narcolepsy:
[blank_start]Overnight Polysomnography[blank_end]: A comprehensive recording of the biophysiological changes that occur during a normal sleep duration
[blank_start]Multiple Sleep Latency Test[blank_end]: Four 25 minute naps around 2 hours apart in order to test brain activity and eye movement
[blank_start]Lumbar puncture[blank_end]: Measures the levels of Hypocretin being produced by the brain
Questão 16
Questão
What is REM Behaviour Disorder (RBD)?
Responda
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A disorder whereby people act out their dreams. The normal atonic nature of muscles during REM sleep is not present.
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A disorder whereby people actively dream during the day. Like narcolepsy, this condition is also related to hypocretin levels in the brain.
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A condition whereby an individual wakes up upon initiation of REM sleep, meaning they must sleep in smaller sections and can never get a full night's sleep.
Questão 17
Questão
Which hormone supplement can be given to REM Behaviour Disorder patients in attempt to improve their sleep?
[blank_start]Melatonin[blank_end]
Questão 18
Questão
Which of the following is the most commonly prescribed medication to treat Narcolepsy?
Responda
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Modafinil
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Sodium Oxybate
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Fluoxetine
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Amitriptyline