Clinical Immunology Test 2- PMU

Descrição

Medicine Immunology Quiz sobre Clinical Immunology Test 2- PMU, criado por Med Student em 11-04-2019.
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Quiz por Med Student , atualizado more than 1 year ago
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5

Resumo de Recurso

Questão 1

Questão
The lymphoid inflitration of thyroidea is typical for
Responda
  • Hashimoto's Thyroiditis
  • Euthroid struma
  • Hemolytic anemia
  • Tuberculosis

Questão 2

Questão
Which method is not useful for detection of specific IgE?
Responda
  • imumonoenzyme techniques (ELISA. immuno blot)
  • classic reactions (agglutination, precipitation)
  • flowcytometry
  • chemiluminescence

Questão 3

Questão
I type allergic reactions are
Responda
  • immuno-complex
  • cytotoxic
  • IgE mediated
  • cell mediated

Questão 4

Questão
Monoclonal antibodies connected with diphtheria toxin could be used for
Responda
  • tumor diagnosis
  • immunostimulation
  • immunosuppressive therapy
  • immunotherapy for tumors

Questão 5

Questão
Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics a. Multiple sclerosis [blank_start]6[blank_end] b. SLE [blank_start]4[blank_end] c. Myasthenia gravis [blank_start]5[blank_end] d. Pernicious anemia [blank_start]1[blank_end] e. Hashimoto thyoiditis [blank_start]2[blank_end] f. Hemolytic anemia [blank_start]3[blank_end] 1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12 2. autoantibodies against thyroglobuline and thyroid peroxidase 3. antibodies against epitopes of red blood cells 4. antibodies against nucleus antigens 5. antibodies against acetylcholine 6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
Responda
  • 6
  • 5
  • 4
  • 3
  • 2
  • 1
  • 4
  • 1
  • 2
  • 3
  • 5
  • 6
  • 5
  • 1
  • 2
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  • 1
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  • 2
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  • 3
  • 1
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  • 5
  • 6

Questão 6

Questão
Which of the following human tumor antigens are connected with melanoma malignuum?
Responda
  • CA 15-3
  • gp 1900
  • MART-1 Melan A
  • gp 120

Questão 7

Questão
Type II allergic reactions are realized through
Responda
  • anaphylaxis
  • complement-mediated cytolysis
  • immune complexes
  • infectious immunity

Questão 8

Questão
EBV can cause development of
Responda
  • hepatoma
  • nasopharyngeal carcinoma
  • the Burkitt lymphoma
  • adenocarcinoma pulmonis

Questão 9

Questão
Anaphylactic reactions
Responda
  • are developed in very short time - 30 min
  • can be followed by inflammatory complication some hours later
  • are result of release of active mediators
  • all answers are correct

Questão 10

Questão
Autoimmune diseases due to antibodies could be a result of: (mark the wrong answer)
Responda
  • generation of antigen-antibody complexes
  • antibody-induced complement mediated cytolysis
  • antibodies that inhibit cell receptor
  • cell-mediated reaction

Questão 11

Questão
The Bence-Jones protein can be find mostly in
Responda
  • urine and serum
  • liquor
  • joint puncture
  • tumor biopsy

Questão 12

Questão
Immuno - scintigraphy uses monoclonal antibodies against tumor antigens connected with
Responda
  • FITC
  • Rodamine
  • Iodine-131, technetium
  • Enzyme

Questão 13

Questão
What as it we can use as a substrate for detecting of antinuclear antibodies with IFA
Responda
  • rat liver
  • rat kidney
  • rat stomach
  • HEp2 cell line

Questão 14

Questão
Point two diseases where we can use the Mantoux reaction [blank_start]Leprosy[blank_end] [blank_start]Tuberculosis[blank_end]
Responda
  • Leprosy
  • Tuberculosis

Questão 15

Questão
CA-15-3 is a marker for first choice in diagnosis of:
Responda
  • Hepatoma
  • Ca glandulae mamme
  • Melanoma malignum
  • Astrocytoma

Questão 16

Questão
III type allergic reaction is developed through
Responda
  • SLE
  • Rheumatoid arthritis
  • Contact dermatitis
  • Acute rheumatism

Questão 17

Questão
The blocking factors secreted from tumor cells during tumor growth
Responda
  • stop cell growth of tumor cells
  • stop the action of Tc-lymphocytes onto tumor cells
  • stop stimulation of tumor specific B-cells
  • are connected with T-lymphocytes and lead to lysis of tumor cells

Questão 18

Questão
Systemic lupus erythematodes
Responda
  • is caused by mutation in dsDNA
  • is an example of T mediated disease
  • is manifested with many symptoms and affect many organs
  • is a result of forming of immune complexes

Questão 19

Questão
The atopic diseases are developed because:
Responda
  • often contacts with allergen
  • they are inheritable
  • they are developed due to immune complexes
  • of IgE

Questão 20

Questão
We find autoantibodies against cytotoxic antigens of neutrophils (ANCA) mainly in
Responda
  • the Goodpasture syndrome
  • amyloidodis
  • granulomatosis of Wegener
  • none of this

Questão 21

Questão
The Bence-Jones protein is
Responda
  • free heavy chains
  • free light κ or λ chains, imperceptible with electrophoresis
  • autoantibodies from IgM class against normal antibodies (IgG) in patients with rheumatoid arthritis
  • fc fragment of complement

Questão 22

Questão
CEA is increased in
Responda
  • nasopharyngeal carcinoma
  • lymphoma Burkitt
  • gastrointestinal tumors
  • smokers

Questão 23

Questão
The most used techniques for detection of antinuclear antibodies antibodies are
Responda
  • direct immmunofluocrescent test
  • indirect immunofluorescent test
  • agglutination
  • neutralization
  • reaction for
  • ELISA

Questão 24

Questão
How fast is the reaction in cases of type 1 hypersensitivity?
Responda
  • after 15-30 minutes
  • after 48 hours

Questão 25

Questão
The most frequent biological carcinogens are
Responda
  • Mycoplasmas
  • Chlamydia
  • DNA- viruses
  • RNA- viruses

Questão 26

Questão
Connect with arrows allergic diseases with relevant type allergic reaction a. Type I [blank_start]3[blank_end] b. Type II [blank_start]4[blank_end] c. Type III [blank_start]1[blank_end] d. Type IV [blank_start]2[blank_end] 1. serum disease 2. contact dermatitis 3. anaphylaxis 4. hemolytic disease of the newborn
Responda
  • 3
  • 1
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  • 4
  • 1
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  • 1
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  • 2
  • 1
  • 3
  • 4

Questão 27

Questão
Glomerutonephritis and vessel diseases due to antibodies are typical for
Responda
  • the Arthus Phenomenon
  • edema angioneuroutic
  • SLE
  • anaemia haemolytica

Questão 28

Questão
Anti-mitochondrial antibodies are mostly
Responda
  • detected in patients with primary biliary cirrhosis
  • detected in patients with rheumatoid arthritis
  • do not harm the organism

Questão 29

Questão
In case of Ca glandulae prostate is increased the serum levels of
Responda
  • PSA (prostate specific antigen)
  • Antibodies against H.pylori
  • Calcitonin
  • Progesterone

Questão 30

Questão
Auto antibodies against microsomes of thyroid cells can be detected in case of
Responda
  • Ca gl. thyroidae
  • Ca renis
  • Pancreatitis
  • Ca pancrei

Questão 31

Questão
Autoimmune hemolytic anemia in developed mostly via
Responda
  • Type I allergic reactions
  • Type II allergic reactions
  • Type III allergic reactions
  • Type IV allergic reactions

Questão 32

Questão
Rheumatoid factor from the serum of patients with rheumatoid arthritis is
Responda
  • IgM reacting with Fc fragment of endogenous IgG
  • IgM reacting wit Fab fragment of IgG
  • IgE reacting with bacterial antigens
  • Acute-phase proteins

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