Transition Block - Immunology

Natural Killer Cells form part of the [blank_start]innate[blank_end] immune system

[blank_start]Adaptive[blank_end] immunity is a key feature required for vaccination

The formation of memory B cells accounts for the rapid production of [blank_start]IgG[blank_end] at re-exposure to a microbe after vaccination.

Targeted biological drugs such as anti-TNF (e.g. adalimumab) are functionally equivalent to [blank_start]passive[blank_end] immunisation

A 22- year old woman is referred to the rheumatology clinic because her fingers change colour in the cold. This has been re-occurring in the year. Her past medical history includes recurrent mouth ulcers and pain in the small joints of her hands. Which antibody will aid diagnosis?

Anti-Jo-1 Antibody is most commonly associated with which inflammatory myopathy? [blank_start]Polymyositis[blank_end]

Which specific anticholinesterase medication is usually given to treat Myasthenia Gravis? [blank_start]Pyridostigmine[blank_end]

Hypersensitivities: [blank_start]Type 1[blank_end]: Immediate Hypersensitivity [blank_start]Type 4[blank_end]: Delayed Hypersensitivity [blank_start]Type 3[blank_end]: Immune Complex Reaction (Complement Dependent) [blank_start]Type 2[blank_end]: Cytotoxic Reaction (Antibody Dependent)

Pemphigus Vulgaris & Bullous Pemphigoid are examples of a [blank_start]Type II[blank_end] Hypersensitivity Reaction

Blood transfusion reactions are an example of a [blank_start]Type II[blank_end] Hypersensitivity Reaction

Systemic lupus erythematosus is an example of a [blank_start]Type III[blank_end] Hypersensitivity Reaction

Tuberculosis is an example of a [blank_start]Type IV[blank_end] Hypersensitivity

Immunodeficiency: [blank_start]Secondary Immunodeficiency[blank_end] = Acquired Immunodeficiency [blank_start]Primary Immunodeficiency[blank_end] = Congenital Immunodeficiency

Common variable immunodeficiency (CVID) is an immune disorder characterized by recurrent infections due to low antibody levels, specifically in which 3 of the following immunoglobulin types?

Anti-CD20 Antibody is an agent which eliminates [blank_start]B Cells[blank_end]

HIV is primarily a disease against ...

Contact Hypersensitivity is a [blank_start]Type IV[blank_end] Hypersensitivity

Despite popular belief, Methotrexate is actually not Hepatotoxic.

IgA anti-TTG autoantibodies are typically present in cases of [blank_start]Coeliac[blank_end] Disease

A woman's Colostrum (first breast milk) mainly contains [blank_start]IgA[blank_end]

Type I Hypersensitivity: Mediated by [blank_start]IgE[blank_end] Type II Hypersensitivity: Mediated by [blank_start]Antibodies[blank_end] Type III Hypersensitivity: Mediated by [blank_start]Immune Complexes[blank_end] Type IV Hypersensitivity: Mediated by [blank_start]T cells[blank_end]

Chronic Transplant Rejection is a [blank_start]Type IV[blank_end] Hypersensitivity Reaction

22q11.2 deletion causing a failure to develop 3rd and 4th pharyngeal pouches leading to congenital heart disease, learning defects and a lack of a thymus is known as [blank_start]Di George[blank_end] Syndrome