Questão 1
Questão
What is atopic eczema?
Responda
-
An inflammatory process affecting the skin
-
Loss of melanocytes from the stratum basale
-
Thinning of the epidermis
Questão 2
Questão
Atopic eczema is not the most common form of eczema.
Questão 3
Questão
What percentage of the population does eczema affect?
Questão 4
Questão
What is the most common age of onset of atopic eczema?
Responda
-
Childhood
-
Middle age
-
Aged 60+
Questão 5
Questão
What conditions are often associated with atopic eczema?
Responda
-
Hayfever
-
Asthma
-
IBS
-
Meningitis
Questão 6
Questão
Histologically, which layer of skin thickens in the chronic stage of eczema?
Responda
-
Epidermis
-
Dermis
-
Subcutis
Questão 7
Questão
In which stage of eczema is the skin likely to be weepy?
Questão 8
Questão
The vesicles that are present during the acute stage of atopic eczema are found....
Questão 9
Questão
Where does infantile atopic eczema usually first present?
Questão 10
Questão
What area of the body does infantile atopic eczema usually spare?
Responda
-
Face
-
Nappy area
-
Hands and feet
-
Torso
Questão 11
Questão
Where does eczema tend to localize to in school-age children?
Responda
-
Flexures
-
Extensor surfaces
-
Hand and feet
-
Between the digits
Questão 12
Questão
What is lichenification?
Responda
-
Thick, leathery skin due to extensive scratching or rubbing of the area
-
Thin, papery skin due to the skin drying out
-
Thickening of the skin due to the skin drying out
-
Skin that has lost its pigment due to excess scratching or rubbing
Questão 13
Questão
Which of the following are common triggers for atopic eczema?
Responda
-
Cleaning products
-
Dust mites
-
Animal fur
-
Pollens
-
Salt water
Questão 14
Questão
What can be used to break the itch-scratch cycle commonly seen in eczema?
Responda
-
Mittens or gloves
-
Steroids
-
Antihistamines
-
Oral antibiotics
Questão 15
Questão
How times a day are emollients usually prescribed for a person with eczema?
Responda
-
Once a day
-
Twice a day
-
Three times a day
-
As required
Questão 16
Questão
How can using soap substitutes help in the treatment of eczema?
Questão 17
Questão
How should steroids be used in the treatment of eczema?
Responda
-
Intermittently to control flare ups, but not on more the 7 days in a month
-
Constantly
-
As required, but not for more than a month at a time
Questão 18
Questão
What treatments can a dermatologist offer for eczema that a GP cannot?
Responda
-
Topical steroids
-
Systemic treatments
-
UV light therapy
-
Calcineurin inhibitors
-
Oral antibiotics
Questão 19
Questão
What are calcineurin inhibitors?
Responda
-
Immunomodulating drugs that block calcineurin receptors
-
Immunomodulating drugs that prevent the production of calcineurin
-
Immunomodulating drugs that decrease the effects of calcineurin by binding to it and changing its shape
Questão 20
Questão
What does calcineurin do?
Responda
-
Activates inflammation within the skin
-
Causes immune cells within the skin to proliferate
-
Aggravates the skin causing inflammation
Questão 21
Questão
Steroids can cause stretch marks or striae on the skin.
Questão 22
Questão
What is the most common bacterial infection that accompanies eczema?
Responda
-
Staphylococcal infection
-
E. Coli infection
-
Streptococcal infection
Questão 23
Questão
What is the most common viral co-infection that accompanies eczema?
Responda
-
Herpes infection
-
Rhotavirus infection
-
Coronovirus infection
Questão 24
Questão
When is hyper- or hypo- pigmentation most likely to occur in eczema?
Questão 25
Questão
Eczema does not cause scarring. True or false?
Questão 26
Questão
Where does psoriasis most often occur on the body?
Responda
-
Flexor surfaces
-
Extensor surfaces
-
Torso
-
Extremities
Questão 27
Questão
Which of these descriptions most accurately describes psoriasis?
Responda
-
Well-defined, inflamed plaques which appear white and scaly
-
Poor-defined, inflamed plaques which appear white and scaly
-
Well-defined, inflamed plaques which appear golden and crusty
-
Poorly-defined, inflamed plaques which appear golden and crusty
Questão 28
Questão
What percentage of the population is affected by psoriasis?
Responda
-
0.1-0.5%
-
1-2%
-
5-7%
-
10-15%
Questão 29
Questão
What is the peak age of onset for psoriasis?
Responda
-
15 years old
-
28 years old
-
40 years old
-
67 years old
Questão 30
Questão
Psoriasis only affects women. True or false?
Questão 31
Questão
Psoriasis usually affects extensor surfaces, but where else can it commonly affect?
Questão 32
Questão
The distribution of psoriasis is usually symmetrical. True or false?
Questão 33
Questão
Histologically, what occurs in psoriasis?
Responda
-
Disordered maturation of keratinocytes
-
Increased epidermal transit time of keratinocytes
-
Thickening of the epidermis
-
Hyperplasia of keratinocytes in the stratum corneum
-
Benign proliferation of Langerhan cells within the epidermis
Questão 34
Questão
How does coal tar help to treat psoriasis?
Responda
-
Slows the growth of keratinocytes
-
Restores the skins appearance
-
Reduces the irritation of the skin
-
Thins the epidermis
-
Slows hair growth
Questão 35
Questão
Why is coal tar not well tolerated?
Responda
-
It can make the skin red and itchy
-
It can stain clothes, bedding and light-coloured hair
-
It causes hair loss
-
Not very much improvement is seen after short-term use
Questão 36
Questão
How is salicylic acid useful in treating psoriasis?
Questão 37
Questão
What is the mechanism of action of vitamin D analogues used in the treatment of psoriasis?
Responda
-
Reduces proliferation of keratinocytes and stimulates epidermal cell differentiation
-
Reduces proliferation of melanocytes and stimulated epidermal cell differentiation
-
Increases proliferation of keratinocytes and stimulates epidermal cell differentiation
-
Reduces proliferation of keratinocytes and reduces epidermal cell differentiation
Questão 38
Questão
What treatments can dermatologists offer for psoriasis that GPs cannot?
Responda
-
Topical steroids
-
UV phototherapy
-
Systemic medications
-
Monoclonal antibodies
-
Emollients
-
Coal tar
Questão 39
Questão
Which wavelength of UV light is used in UV phototherapy?
Questão 40
Questão
Why are oral retinoids given before a course of UV phototherapy?
Responda
-
To enhance the effects of the UV phototherapy
-
To sedate the patient
-
To ensure the patient does not experience and nausea or vomiting
-
To reduce the risk of DNA damage to skin cells
Questão 41
Questão
What is the course of treatment for UV phototherapy?
Responda
-
2-3 times per week for 3-4 months
-
As required
-
6 times per week for a month
-
Once per week for one year
Questão 42
Questão
What is the cause of acne vulgaris?
Responda
-
Over-activity of pilo-sebaceous glands
-
Over-activity of apocrine sweat glands
-
Over-activity of eccrine sweat glands
-
Under-activity of pilo-sebaceous glands
Questão 43
Questão
What causes the over stimulation of the sebaceous glands?
Questão 44
Questão
How does the over stimulation of the sebaceous glands then lead to acne?
Responda
-
The hair follicles become "plugged" with secretions
-
Inflammation occurs within the hair follicles
-
Hair growth is too fast due to increased sebum leading to the follicle becoming blocked
Questão 45
Questão
Where on the body is acne most common?
Responda
-
Face
-
Upper chest and back
-
Hands
-
Scalp
Questão 46
Questão
Why is acne most common on the face, upper chest and upper back?
Responda
-
Because the highest population of sebaceous glands is found here
-
Because these areas are often exposed
-
Because these areas are most often touched with dirty hands
Questão 47
Questão
How many grades of severity are there for acne vulgaris?
Questão 48
Questão
What do topical retinoids do?
Questão 49
Questão
How should systemic retinoids not be given to?
Questão 50
Questão
How is the oral contraceptive pill useful in treating acne?
Responda
-
It controls the hormones to prevent over stimulation
-
It makes sebum less viscous preventing "plugging" of the hair follicles
-
It makes hair follicles larger so that they become "plugged" less easily
-
It is used in women and girls to give a placebo effect
Questão 51
Questão
Both oral and topical antibiotics can be used to treat acne vulgaris. True or false?
Questão 52
Questão
What type of infection is impetigo?
Questão 53
Questão
Which bacteria are most commonly responsible for impetigo?
Questão 54
Questão
What feature is very characteristic of impetigo?
Questão 55
Questão
What two treatments are most commonly used to treat impetigo?
Responda
-
Fucidin cream
-
Oral flucloxadin
-
Topical penicillin
-
Emollients
-
Methotrexate
-
Topical dexamethasone
Questão 56
Questão
What virus usually causes viral warts?
Questão 57
Questão
How are viral warts most commonly transmitted?
Questão 58
Questão
Viral warts are often self-resolving. True or false?
Questão 59
Questão
Which of the following is not a treatment for viral warts?
Questão 60
Questão
Tinea and roundworm are different skin conditions. True or false?
Questão 61
Questão
What is tinea caused by?
Responda
-
A bacteria
-
A virus
-
A fungus
Questão 62
Questão
What is the usually given as treatment for tinea?
Responda
-
Topical anti-fungals
-
Topical antibiotics
-
Emollients
-
Topical corticosteroids
Questão 63
Questão
Systemic treatment is never used for tinea infection. True or false?
Questão 64
Questão
What causes actinic keratosis?
Responda
-
Sun exposure
-
Benign proliferation of melanocytes
-
Hormonal over-stimulation
-
Wear and tear of the skin over time
Questão 65
Questão
In what age group is actinic keratosis most common?
Responda
-
Over sixties
-
Forties to fifties
-
Teenagers
-
Infants
Questão 66
Questão
Why must actinic keratosis be closely observed?
Responda
-
Because it can develop into skin cancer
-
Because as it increases in size it can become very painful
-
Because if a person has more than three lesions they may have liver cirrhosis
Questão 67
Questão
What skin cancer is actinic keratosis most likely to develop into?
Responda
-
Melanoma
-
Squamous cell carcinoma
-
Basal cell carcinoma
Questão 68
Questão
What treatments are there for actinic keratosis?
Responda
-
Cryptherapy
-
Emollients
-
Topical corticosteroids
-
Systemic retinoids
-
Oral antibiotics
Questão 69
Questão
Which type of skin cancer is considered to be the least serious?
Responda
-
Basal cell carcinoma
-
Squamous cell carcinoma
-
Melanoma
Questão 70
Questão
Where on the body does basal cell carcinoma most commonly present?
Responda
-
Head and neck
-
Hands and arms
-
Torso
-
Any sun exposed area
Questão 71
Questão
What is the appearance of a basal cell carcinoma lesion?
Responda
-
Shiny, translucent nodule
-
Dark, asymmetrical lesion
-
Inflamed, crater-shaped lesion
Questão 72
Questão
Why is basal cell carcinoma not referred under the two week wait rule?
Responda
-
Because it very rarely metastasizes
-
Because nothing can be done to remove this cancer
-
Because too many people get this type of cancer for the NHS to deal with
Questão 73
Questão
Squamous cell carcinoma only arises from actinic keratosis. True or false?
Questão 74
Questão
What is squamous cell carcinoma caused by?
Questão 75
Questão
What features of a skin lesion would make it suspicious?