Questão 1
Questão
All cells have the same genes. True or false?
Questão 2
Questão
Which of these are examples of house-keeping genes?
Responda
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Glycolysis enzymes
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DNA polymerase
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Genes that code for haemoglobin
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Genes that code for melanin
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Genes that code for the cytoskeleton
Questão 3
Questão
What are the types of transcript?
Responda
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Abundant transcript
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Rare transcript
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No transcript
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Positive transcript
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Negative transcript
Questão 4
Questão
To what level are house-keeping genes normally transcribed?
Responda
-
Abundant transcript
-
Rare transcript
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No transcript
Questão 5
Questão
When might genes that usually have no transcript be transcribed?
Responda
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During development
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In response to a stimuli
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In disease states
Questão 6
Questão
The amount that genes are transcribed cannot be altered. True or false?
Questão 7
Questão
What are transcription factors?
Responda
-
Proteins that bind to DNA to prevent or allow transcription to occur
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Proteins that bind to DNA and unwind it initiating transcription
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Proteins that bind to RNA polymerase making it more efficient
Questão 8
Questão
What two transcription factors are present in the Lac Operon?
Responda
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CAP Protein
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Lac represser
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Lac ZYA
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TATA proteins
Questão 9
Questão
Where do transcription factors bind to in eukaryotes?
Responda
-
The major groove in DNA
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The minor groove in DNA
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The promoter
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The telomere
Questão 10
Questão
Why do transcription factors bind to the major groove?
Responda
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The base pairs are not exposed in the minor groove
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There are more binding sites in the major groove
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The major groove is more recognizable
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There is not enough room in the minor groove
Questão 11
Questão
Transcription factors have to unwind DNA to find their binding point. True or false?
Questão 12
Questão
What are TATA boxes?
Responda
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A part of DNA made up of many thymines and adenines which act as a binding site for transcription factors
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An area of DNA where thymine and adenine alternate for more then 100 base pairs to signal the end of an intron
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An area of DNA where thymines and adenines are added gradually throughout life that scientists use to estimate the age of someone
Questão 13
Questão
What transcription factor binds to TATA boxes?
Questão 14
Questão
What are regulatory elements?
Responda
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Specific patterns that are recognized by regulatory factors
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Generic patterns that are recognized by a variety of regulatory factors
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Palindromic patterns in DNA that are recognized by regulatory factors
Questão 15
Questão
In eukaryotes, often it requires many transcription factors to lead to transcription. True or false?
Questão 16
Questão
Are histones positively or negatively charged?
Questão 17
Questão
Why do histones need to positively charged?
Responda
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So they can bind to DNA
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So they can move through the nuclear membrane
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So they can move through the cell membrane
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So they don't interact with protein synthesis
Questão 18
Questão
How do transcription factors make histones disassociate from DNA?
Responda
-
They acetylate them so there is no positive charge
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They give DNA in that area a neutral charge so the histones can no longer bind to it
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They add chloride ions to the histones to make them negatively charged
Questão 19
Questão
Why is it necessary to disassociate the histones from DNA?
Responda
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So that transcription can occur
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So DNA can be replicated
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So that DNA can coil up tight enough to fit within the nucleus of the cell
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To allow DNA to be studied under a microscope
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To allow DNA to form its double helix shape
Questão 20
Questão
The less differentiated a cell is the more likely it is able to go back to its undifferentiated state. True or false?