Questão 1
Questão
Which of the following methods is suitable for detectin of serum globulins?
Questão 2
Questão
Type II allergic reations are realized by
Questão 3
Questão
Monoclonal antibodies are
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pure population of immunoglobulins with same structure ant antigen specifity
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albumins that are coded from other group of genes
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mixed population of immunoglobulins with same structure, but different antigen specifity
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substrate causing expression of immunoglobulins from other class in B-cells
Questão 4
Questão
Which immunological method is not proper for detecting of specific IgE
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Immuno-enzyme(ELİSA, immuno-blot technique)
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Classical ones(agglutination, precuipitation)
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Floucytometry
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Chemilluminescence
Questão 5
Questão
Low levels of IgA are found in case of
Questão 6
Questão
Auto immune disease due to antibodies could be a result of (point the wrong answer)
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forming of antigen-antibody complexes
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antibodies that blockade cell receptor
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antibody-depended cell-mediated cytotocicitty(ADCC)
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cell-mediated reaction
Questão 7
Questão
The name of resident macrophages in liver is
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ostephages
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lagerhance cells
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kupfer cells
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microglial
Questão 8
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Hepatoma
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Nasopharyngeal carcinoma
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Burkit lymphoma
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Adenocaqrcinoma pulmonis
Questão 9
Questão
Which of the following indicators is the most important in case of detecting of immune status in AIDS
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NBT test
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Anti-DNA antibodies
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CD4/CD8 index
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The bence-jones protein
Questão 10
Questão
System lupus erythematosus
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is caused by mutations in ds-DNA
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is revealed with many symptoms and affects many organs
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is an example of T-cell mediated disease
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is a result of generating of immune complexes
Questão 11
Questão
The opsonisation is a process of
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Ingestion and destruction of an antigen from phagocyte
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Of covering of antigen with antibodies in purpose to ease phagocytosis
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Of covering of antigen with complement in purpose to ease phagoytosis
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Obtaining of monoclonal antibodies
Questão 12
Questão
Connect with arrows allergic diseases with relevant types allergic reactions:
Type [blank_start]3[blank_end] - serum-disease
Type [blank_start]4[blank_end] - contact dermatitis
Type [blank_start]1[blank_end] - anaphylaxis
Type [blank_start]2[blank_end]- hemolytic disease of newborn
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3
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1
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2
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4
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4
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1
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2
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3
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1
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3
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4
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2
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1
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3
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4
Questão 13
Questão
The mature B-lymphocytes expresses onto their surface
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IgM and IgD
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IgM and IgA
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IgD and IgE
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IgG and IgD
Questão 14
Questão
The lymphocyte infiltration of thyroidea is typical for
Questão 15
Questão
The electrophoresis is
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radial immunodiffusion in gel
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separation of molecules in electric field
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complement fixation reaction
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electroimmunodiffusion
Questão 16
Questão
I type allergic reactions are
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Immunocomplex
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Cytotoxic
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IgE mediated
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Cell mediated
Questão 17
Questão
Connect with arrows autoimmune diseases from the left side with relevant characteristics from the right side: wide with relevant characteristics
a. Multiple sclerosis [blank_start]6[blank_end]
b. SLE [blank_start]4[blank_end]
c. Myasthenia gravis [blank_start]5[blank_end]
d. Pernicious anemia [blank_start]1[blank_end]
e. Hashimoto thyoiditis [blank_start]2[blank_end]
f. Hemolytic anemia [blank_start]3[blank_end]
1. autoantibodies against parietal cells of stomach ans intrinsic factor and as a result of this doesn't absorb Vitamin B12
2. autoantibodies against thyroglobuline and thyroid peroxidase
3. antibodies against epitopes of red blood cells
4. antibodies against nucleus antigens
5. antibodies against acetylcholine
6. antibodies against morbidly antigens in liquor and serum, depressed reactions of delayed type hypersensitivity against measles antigens
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6
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1
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5
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4
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1
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2
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4
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5
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6
Questão 18
Questão
The monoclonal antibodies, connected with diphtheria toxin could be used for
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tumour diagnosis
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immunostimulation
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immunosupperession
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immunotherapy of tumors
Questão 19
Questão
The defensins are
Questão 20
Questão
What is the mechanism of III type allergic reactions
Questão 21
Questão
Which of the following tumour markers are connected with melanoma maligna?
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CA-15-3
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gp 120
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S100B
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MART-1Melan A
Questão 22
Questão
Immuno-scintigraphy uses monoclonal antibodies against tumour antigen connected with
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FITC
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Rhodamine
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Iodine 131, technetium
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Enzyme
Questão 23
Questão
INF-γ is produced by
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Activated T lymphocytes
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Fibroblasts
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B-lymphocytes
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Leucocytes
Questão 24
Questão
What kind of auto-antibodies we find in patients with insulin-depended sugar diabetes?
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Nucleus
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Thyroid microsomes
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IgG molecules
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Island cells of pancreas
Questão 25
Questão
Rejection of a transplantant due to pre-forming antibodies in recipient is defined as
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Hyper acute rejection
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Accelerated
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Acute
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Chronic
Questão 26
Questão
What of the following possesses the most expressed oncogenic potential
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Influenza virus type A
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Ebola virus
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EBV
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Polioviruses 1,2 ,3
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HPV
Questão 27
Questão
Is the following correct?
Active immunity is a nospecific and is an ancient form of defense and lower degree of effectiveness?
Questão 28
Questão
Type IV allergic reactions are realized by means of
Questão 29
Questão
True hypersensitivity reactions start usually after
Questão 30
Questão
Which of the following characteristics does not belong to the Burkit lymphoma?
Questão 31
Questão
Antigen presenting cells are
Questão 32
Questão
We could use the mantoux test in diagnosis of (point two diseases)
a- [blank_start]Tuberculosis[blank_end]
b- [blank_start]Leprosy[blank_end]
Questão 33
Questão
Which of the following factors belong to the innate immunity?
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Phagocytosis
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T-lymphocytes
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Complement, mucin, a-and b inferferons
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Antibodies
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Skin, mucus, normal flora
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B-lymphocytes
Questão 34
Questão
What we could use as a subsrrate for detection of antinuclear antibodies throguh IFA?
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rat liver
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rat kidney
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rat stomach
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hep2 cell line
Questão 35
Questão
Which of the pointed immunological parameters is most important for detection of multiple myleoma?
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NBT test
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Anti-DNA antibodies
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CD4/CD8 index
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The Bence-jones protein
Questão 36
Questão
The most popular techniques for detection of antinuclear antibodies are
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Agglutination
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Indirect immunofluorescence
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Neutralization test
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The complement fixation test
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ELISA
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Direct immunofluorescence
Questão 37
Questão
CD3 molecule is a marker for
Questão 38
Questão
The accelerated reaction for rejection of transplantant is revealed
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Intra-operative or immediately after operation
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24-to 72 hours after transplantation
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Till the third month
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3 month after the transplantation
Questão 39
Questão
which of the following immunological indexes ids the most important for patients with chronic granulomatous disease?
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NBT test
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Anti DNA antibodies
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CD4/CD8 index
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The Bence-jones protein
Questão 40
Questão
CEA is increased in case of
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nasopharyngeal carcinoma
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the Burkit lymphoma
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gatro-intestinal tumors
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smokers
Questão 41
Questão
Which of the following is connected with damage of humoral immunity?
Questão 42
Questão
How many are complement activating ways?
Questão 43
Questão
The complement activation occurs via three pathways which are:
1. [blank_start]Classical[blank_end] pathway
2. [blank_start]Alternative[blank_end] pathway
3. [blank_start]Lectin[blank_end] pathway
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Classical
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Alternative
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Lectin
Questão 44
Questão
The “respiratory burst" is related to
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Humoral immunity
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Cellular immunity
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Phagocytosis
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NK-cells function
Questão 45
Questão
The immune competence of T-lymphocytes is acquired in
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Thyroidea
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Bone marrow
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Thymus
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MALT
Questão 46
Questão
What expresses the CD8 molecule?
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Macrophages
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Antigen presenting cells
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Cytotoxic T-lymphocytes
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T- suppressors
Questão 47
Questão
What is human cell receptor for human immunodeficiency virus (HIV)?
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CD3 molecule
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CD8 molecule
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CD4 molecule
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CD19 molecule
Questão 48
Questão
Point the WRONG answer:
Gamma interteron is produced by:
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Non-activated macrophages and mastocytes
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Leucocytes and Fibroblasts
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Activated macrophages and NK cell
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Lymphocytes
Questão 49
Questão
The determination of functional activity of the complement might be done by
Questão 50
Questão
CD4 molecule is situated on the surface of the
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Monocytes
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T-helpers
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Cytotoxic T-lymphocytes
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Plasmocytes
Questão 51
Questão
The presence of the antigen together with the MHC-II class molecules is realized by
Questão 52
Questão
A B-cell can synthesise some different antibodies with different species of the antigen
Questão 53
Questão
After the antigen stimulus the mature B-lymphocytes are transformed into
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cytotoxic cell
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immunocompetent cell
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plasmocyte
Questão 54
Questão
What tests are for evaluation of the phagocytic activity?
Questão 55
Questão
Paraproteinemias are detected in
Questão 56
Questão
Last cells, incapable to divide are
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Plasmocytes
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Neutrophils
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T-lymphocytes
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B-Iymphocytes
Questão 57
Questão
What do the mature B-lymphocytes express on their surface?
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lgM and IgD
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IgD ant IgE
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IgM and IgA
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IgG and IgD
Questão 58
Questão
How do CD8 eliminate their targets?
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after recognition of antigen, connected with MCH-I class molecule
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after recognition of antigen connected with MCH-II class molecule
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via activation of an alternative way of complement
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due releasing of interferon