Questão 1
Questão
Which of the following is not a sign of acute inflammation?
Responda
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Pain
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Functio Laesa
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Swelling
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Erythema
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Warmth
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Angiogenesis
Questão 2
Questão
List the main components of the 1st (vascular) phase of acute inflammation.
Responda
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Vascular dilation --> smooth muscle relaxation --> endothelial cell contraction --> increase in vascular permeability
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Smooth muscle relaxation --> vascular dilation --> endothelial cell contraction --> increase in vascular permeability
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Endothelial cell contraction --> increase in vascular permeability --> vascular dilation --> smooth muscle relaxation
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Endothelial cell contraction --> increase in vascular permeability --> smooth muscle relaxation --> vascular dilation
Questão 3
Questão
Bradykinin has effects similar to histamine, but these effects become evident later in the inflammation process.
Questão 4
Questão
Your patient has been bitten by a venomous snake. You would expect activation of the complement cascade through which pathway?
Responda
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Classical pathway
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Alternative pathway
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Lectin pathway
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Complement pathway
Questão 5
Questão
Nitric oxide, prostaglandins, leukotrienes, cytokines and PAF are all examples of
Responda
-
Plasma-derived mediators of inflammation
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Cell-derived mediators of inflammation
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Complement-derived mediators of inflammation
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Lymphocyte-derived mediators of inflammation
Questão 6
Questão
The process by which leukocytes are marginalized and become attached to the endothelium of vessels is called
Responda
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Margination
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Pavementing
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Exudation
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Diapedesis
Questão 7
Questão
IL-1 and TNF are the primary endogenous pyrogens released from leukocytes or macrophages
Questão 8
Questão
Which major cell types would you expect to see in the 3rd (organization) stage of wound healing and repair?
Questão 9
Questão
Wound healing by first/primary intention includes: formation of a scab, scavenger action of PMNs, formation of granulation tissue, and scarring.
Questão 10
Questão
With persistent injury that leads to chronic inflammation,
Responda
-
the symptoms are prominent
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CT proliferation occurs as inflammation subsides
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Exudate is comprised of neutrophils
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Exudate is comprised of lymphocytes and macrophages
Questão 11
Questão
A patient's kidney was affected by inflammation for 2-3 months. What type of cells would you expect to see in the tissue?
Responda
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Lymphocytes
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Macrophages
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Fibroblastic scarring
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Plasma cells
Questão 12
Questão
You are observing tissue slides and see many multinucleated giant cells. What underlying reaction/inflammation probably caused this?
Responda
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Granulomatous
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Ulcerative
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Pseudomembranous
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Acute
Questão 13
Questão
Which of the following chemotaxins are endogenous?
Responda
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Necrotic cells
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Fibrinopeptides
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Lipopolysaccharide
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IL-8
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LTB4
Questão 14
Questão
Under ____ conditions, phagocytosis involves a respiratory burst and killing by way of free radicals. This form of phagocytosis _____ contained within the cell.
Responda
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anaerobic; is
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anaerobic; is not
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aerobic; is
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aerobic; is not
Questão 15
Questão
Macrophages appear at the site of inflammation 3-4 days after onset of infection/trauma and are typically present in chronic inflammation.
Questão 16
Questão
Which of the following pathologies are characterized by serous inflammation, the mildest form of inflammation?
Questão 17
Questão
Which of the following complication(s) are associated with granulomas?
Questão 18
Questão
Which of the following cell types do not divide regularly, but can be stimulated to divide if necessary?
Responda
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Stable cells
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Labile cells
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Permanent cells
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Mitotic cells
Questão 19
Questão
Which of the following is not a factor that can significantly delay wound healing?
Responda
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Site of the wound
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Mechanical factors
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Age
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Nurtritional factors
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Vitamin C intake
Questão 20
Questão
You observe the following signs in your patient: leukocytosis, fever, increased CRP and increased ESR. What causes the increase in hepatic synthesis of CRP?
Questão 21
Questão
In early wound organization of granulation tissue you would likely see
Questão 22
Questão
Albumin, synthesized by the liver and pancreas, is the major protein generating vascular oncotic pressure.
Questão 23
Questão
Non-inflammatory edema is characterized by
Questão 24
Questão
Which of the below options are clinical examples of edema?
Responda
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Cirrhosis of the liver
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CHF
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Nephrotic syndrome
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Lymphatic obstruction
Questão 25
Questão
Blushing of the cheeks is an example of passive hyperemia.
Questão 26
Questão
A "nutmeg" liver is the result of
Responda
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hepatic congestion due to left heart failure
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one too many "cinnamon challenges"
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hepatic congestion due to right heart failure
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hepatic steatosis
Questão 27
Questão
Factors increasing one's risk for hemorrhage include:
Questão 28
Questão
Metrorrhagia is defined as profound menstrual bleeding and is considered a form of hemorrhage.
Questão 29
Questão
Arterial rupture is often due to weakening of the vessel walls and venous rupture is often due to injury.
Questão 30
Questão
A 65-year-old female alcoholic is found to have sever liver cirrhosis and facial edema. Which of the following directly contributes to this form of edema?
Responda
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Decreased lymphatic flow
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Decreased oncotic pressure
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Increased venous pressure
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Decreased arterial pressure
Questão 31
Questão
Which of the following substances provides a framework for a clot?
Responda
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Thrombin
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RBCs
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Plasmin
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Fibrin
Questão 32
Questão
A healthcare worker develops a small thrombus in their lower leg. What is the most likely fate of the thrombus?
Questão 33
Questão
A 70-year-old male has a hard time catching his breath and has a dry cough that worsens at night. Diffuse pulmonary edema is noted. The cause of this patient's edema is right-sided heart failure.
Questão 34
Questão
Twin brothers present to your ED with acute conditions; one with volvulus and one with testicular torsion. With respect to the damaged tissues, you would expect to see a RED infarct in these cases.
Questão 35
Questão
You are a pathology PA are looking at an area of tissue that looks to be consistent with a pale/white infarct that is mottled. Which of the following injuries/mechanisms could explain this?
Responda
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Pulmonary infarction that is now receiving blood from bronchial arteries
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Hepatic infarction perfused by collateral vessels after a few days
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Myocardial infarction perfused by collateral vessels after a few days
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This description is highly unlikely
Questão 36
Questão
A patient, known to be in shock, is hypotensive, acidotic, and has oliguria. What stage of shock is the patient probably in?
Responda
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Compensated
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Decompensated
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Irreversible
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Cardiogenic
Questão 37
Questão
A paradoxical embolus is a venous embolus that travels to the arterial circulation via the foramen ovale or interventricular septal defect.
Questão 38
Questão
Intravascular coagulation is the result of the interaction of which factors?
Responda
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Coagulation proteins
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Hemodynamic changes
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Platelets
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Endothelial cells
Questão 39
Questão
Virchow's triad comprises the three predisposing conditions for pathologic thrombi including: endothelial cell injury, hypocoagulability of the blood and hemodynamic changes.
Questão 40
Questão
Alternating bands of RBCs and platelets/fibrin, also known as Lines of Zahn, appear in venous clots due to the dynamic nature of blood flow.