Questão 1
Questão
Which form of Glycogen Phosphorylase is relatively inactive?
Responda
-
Phosphorylase A
-
Phosphorylase B
Questão 2
Questão
In phosphorylase B, where is the N terminus?
Questão 3
Questão
Which of the forms of glyocgen phosphorylase is most effected by cellular AMP/ATP levels?
Responda
-
Phosphorylase A
-
Phosphorylase B
Questão 4
Questão
Which of the following phosphorylates Glycogen Phosphorylase?
Responda
-
Phosphorylase B Kinase
-
Phosphorylase A Kinase
-
Phosphorylase Kinase
Questão 5
Questão
What protein causes the dephosphorylation of phosphorylase?
Responda
-
Protein phosphatase
-
Protein phosphorylase
-
Prokein Kinase P
Questão 6
Questão
What is needed for the reaction of Phosphorylase B --> A to reverse itself?
Responda
-
Water (and a lack of inhibiting AMP)
-
Water (and a lack of inhibiting ATP)
-
Water (and a lack of inhibiting GMP)
Questão 7
Questão
What is different about Phosphorylase A to B?
Responda
-
Ser14 has been phosphorylated
-
Tyr14 has been phosphorylated
-
Thr14 has been phosphorylated
Questão 8
Questão
What difference does phosphorylating Glycogen phosphorylase make?
Questão 9
Questão
How does phosphorylase B Kinase connect Glycogen Phosphorylase levels to the level of stimulation?
Responda
-
It is activated by Ca2+- when the muscle is stimulated, glucose is needed and so glycogen is broken down
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It is deactivated by Ca2+- when the muscle is stimulated, glucose is not needed and so glycogen isn't broken down
Questão 10
Questão
What part of Phosphorylase B Kinase binds to Calcium?
Responda
-
Calmodulin
-
Calsequestrin
-
Troponin C
Questão 11
Questão
Which parts of phosphorylase B kinase are regulatory?
Responda
-
Alpha and beta
-
Alpha and gamma
-
Gamma and beta
Questão 12
Questão
Which part of phosphorylase B kinase is catalytic?
Questão 13
Questão
In phosphorylase B kinase's Ca2+ binding sites, what are the affinities?
Responda
-
2 high
2 low
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4 high
-
4 low
Questão 14
Questão
What protein causes the phosphorylation of Phosphorylase B Kinase?
Questão 15
Questão
What is another name of cAMP dependent protein kinase?
Responda
-
Protein Kinase A
-
Protein Kinase B
-
Protein Kinase C
Questão 16
Questão
What is the role of inhibitor one?
Responda
-
To bind to protein phosphatase, activating it
-
To bind to protein phosphatase, inhibiting it
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To bind to protein kinase A, activating it
Questão 17
Questão
What is contained in the N terminus domain of Glycogen Phosphorylase?
Questão 18
Questão
How does glycogen get from it's binding domain to the catalytic site?
Responda
-
A hydrophobic tunnel
-
A hydrophillic tunnel
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A lipophobic tunnel
Questão 19
Questão
Why is glycogen phosphorylase's site in a deep groove?
Responda
-
To prevent AMP from entering
-
To prevent ATP from entering
-
To prevent water from entering
Questão 20
Questão
What happens if water enters the active site?