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609767
Insulin Receptors
Description
Year 2 (Insulin & Glucagon) Quiz on Insulin Receptors, created by gina_evans0312 on 06/03/2014.
No tags specified
clinical biochemistry
insulin & glucagon
year 2
insulin & glucagon
Quiz by
gina_evans0312
, updated more than 1 year ago
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Created by
gina_evans0312
over 10 years ago
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Resource summary
Question 1
Question
Where is the carboxylase termunus regulatory region found?
Answer
Inside the cell
Outside the cell
In the membrane
Question 2
Question
How are the alpha and beta chains connected?
Answer
Electrostatic interactions
Disulphide bonds
Question 3
Question
What is the active site of insulin receptor?
Answer
Tyrosine kinase
Skeletons
Toast
Question 4
Question
The active site of Insulin receptors work exactly the same as other tyrosine kinases
Answer
True
False
Question 5
Question
What does IRS stand for?
Answer
Inland Revenue Service
Insulin Receptor Substrate
Question 6
Question
There are six different versions of the IRS
Answer
True
False
Question 7
Question
How does the IRS bind to the Insulin receptor?
Answer
PTB- Phosphotyrosine Binding Site
PSB- Phosphoserine Binding Sire
Question 8
Question
The Insulin Receptor response pathway is the same as the MAPK pathway until MAPK activates
Answer
Insulin Sensitive Protein Kinase (ISPK)
Insulin Responsive Protein Kinase (IRPK)
Insulin Dependent Protein Kinase (IDPK)
Question 9
Question
ISPK activates Protein Phosphatase 1, which reverses te effect of adrenaline/glucagon through phoshphorylation
Answer
True
False
Question 10
Question
IRS can also work through the PI3K pathway, leading to the conversion of PI2 to what?
Answer
PI
PI3
PI-2,5-BP
Question 11
Question
The action of the PI3K pathway causes the activation of PKB
Answer
True
False
Question 12
Question
The P of PKB causes the P and deactivation of what?
Answer
Glycogen Synthase Kinase-3
Glycogen Phosphorylase
Question 13
Question
Why does PKB increase phosphodiesterase activity?
Answer
Reverses phosphorylation done by glucaon
Lowers cAMP
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