444041
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
quase 11 anos atrás
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Questão 1
Questão
The complimentation test is used to find out if mutations are allelic or non allelic
Responda
- True
- False
Questão 2
Questão
In what circumstances will a Complimentation Test give a false result?
Responda
-
When the mutation is recessive
-
When the mutation is dominant
-
When the mutated gene is part of a complex
-
Where proteins form multimers
Questão 3
Questão
Genotypes M1 & M2 are bred together, and a Wild Type result is obtained- are the mutations allelic
Responda
-
No- as the presentation of a wild type phenotypes shows there is at least one dominant wild type allele for each gene
-
Yes- The two mutations on the same allele are able to compliment each other sufficiently to produce a wild type phenotype
Questão 4
Questão
If M3 and M2 are bred together and they present as M2, what does this tell us about the mutation's location?
Responda
-
They are on the same allele- there is no dominant wild type allele to mask their activity
-
They are on separate alleles, but M2 has a far greater effect than previously thought
Questão 5
Questão
According to the above table, which mutations are allelic
Responda
-
M9 & M4
-
M8 & M6
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M2
-
All of the above
Questão 6
Questão
A Complimentation Test can be fooled if the mutant protein can form a functioning heterodimer with the wild type protein
Responda
- True
- False
Questão 7
Questão
One gene is said to be epistatic to another if...
Responda
-
The presence of a double mutant exhibits the phenotype of the mutant gene
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The presence of the wild type masks the phenotype of the mutant gene
-
A genes expression causes a change in the expression of another gene further down the pathway
Questão 8
Questão
Where are epistatic genes usually found in substrate dependent pathways?
Responda
-
Upstream
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Downstream
Questão 9
Questão
A substrate dependent pathway is a series of positive and negative regulators that act on one another of the final product
Responda
- True
- False
Questão 10
Responda
- True
- False
Questão 11
Questão
Why should null alleles be used for epistatic analysis (i.e how to find out the order of gene function in a pathway)
Responda
-
The masking of alleles downstream becomes obvious
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They are easier to make than hypomorphic alleles
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They can be used for both Substrate Dependent and Switch pathways
Questão 12
Questão
How do we identify that the pathway effected by the (epistatic) mutation is a Switch Regulatory pathway?
Responda
-
If the mutation prevents the production of the final product
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If the phenotype of a double mutant is different to the phenotype of either single mutant
Questão 13
Questão
The Rif1 & Rif2 strains are both causes lengthened telomeres, as shown in the diagram. Based on the Rif1/Rif2 double mutation, which of the two availible pathways (shown) is likely to be the one used?
Image:
Rif1 (image/png)
Responda
-
Pathway A
-
Pathway B
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