445668
Descrição
Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312
aproximadamente 11 anos atrás
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Questão 1
Questão
Which of the following can cause double strand breaks in the DNA?
Responda
-
Ionising radiation
-
Meiosis
-
Chemicals
-
DNA replication errors
Questão 2
Questão
What are Chromosome Fragile Sites?
Responda
-
Sites where double strand breaks are likely to occur
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Sites that can be easily split accidentally by protein machinery
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Sites that are likely to warp during heat shock
Questão 3
Questão
Chromosome fragile sites are thought to be caused by difficulties during meiosis
Responda
- True
- False
Questão 4
Questão
What does NHEJ stand for?
Responda
-
Non-homologous end joining
-
Non-homologous editing joints
-
Non-heterodimeric end joints
Questão 5
Questão
What are the requirements for NHEJ?
Responda
-
Double strand breaks
-
Single strand breaks
-
T-T lesions
-
DNA ligase 4
-
DNA ligase 2
Questão 6
Questão
The repair process of NHEJ will join any 2 free ends together, regardless of homology
Responda
- True
- False
Questão 7
Questão
An error in NHEJ can lead to translocation between which chromosomes, forming what type of chromosome fusion?
Responda
-
Philadelphia chromosome
-
Inverted chromosome
-
8 &12
-
9 & 22
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13 & 21
Questão 8
Questão
The repair process of Homologous Recombination relies on what?
Responda
-
That the damaged sequence in the sister chromatid is intact
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That the damaged sequence in the homologous chromosome is intact
-
That the damaged sequence in the other allele is intact
Questão 9
Questão
What is required for an error in Homologous Recombination?
Responda
-
A faulty alignment of the two chromosomes
-
A faulty alignment of the two chromatids
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Due to inversions
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Due to translocations
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Due to repeats
Questão 10
Responda
-
NHEJ
-
Homologous Recombination
Questão 11
Questão
A fault in Homologus Recombination can lead to alleles being lost
Responda
- True
- False
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