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985233
Malignancies
Descrição
Pathophysiology and pharmacology of malignancies lecture
Sem etiquetas
medicine
health
healthcare
pathology
physiology
pharmacology
nursing science 3
quizzes
masters
Quiz por
Mark George
, atualizado more than 1 year ago
Mais
Menos
Criado por
Mark George
mais de 10 anos atrás
136
0
0
Resumo de Recurso
Questão 1
Questão
Which of the following are features of cancer cells?
Responda
autonomic & immortal
static & aplastic
transformational & variable
anaplastic & lacking apoptosis
Questão 2
Questão
Which of the following can act as tumor markers?
Responda
proteins
vitamins
hormones
antibodies
antigens
Questão 3
Questão
Tumor markers can confirm diagnosis of some cancers.
Responda
True
False
Questão 4
Questão
Which of the statements below is FALSE?
Responda
Pheochromocytoma is a tumor of the adrenal medulla.
Adrenaline can act as a tumor marker.
PSA is a tumor marker specifically for prostate cancer
Tumor markers can be found in blood, urine and CSF.
Questão 5
Questão
Gene mutations can result in...... (Select the INCORRECT answer)
Responda
Repeated division of telomeres.
Activation of tumor suppression genes.
Cancer cells stimulating angiogenesis
Stimulation of growth promotion pathways
Transformation of proto-oncogenes into oncogenes.
Questão 6
Questão
Regarding the contribution of obesity to cancer, which of the following statements are true?
Responda
BMI greater than 30 linked to cancer.
The endocrine and metabolic activity of adipose tissue is thought to contribute to cancer development
The increased release of FFA and TNF is thought to contribute to cancer development
Increased levels of insulin is also linked to cancer development.
Questão 7
Questão
Which of the following sets of factors all increase the risk of cancer development?
Responda
CHronic inflammation, over-exertion, poor diet and television.
Viruses, bacteria, chronic inflammation and environmental factors
smoking, radiation, alcohol and shopping
Ulcerative colitis, chronic asthma, physical inactivity and Epstein Barr Virus
Questão 8
Questão
Select the true statements regarding pharmacological management of cancer.
Responda
Narcotic analgesics act to inhibit the release of substance P
Adverse effects of narcotic analgesics include diarrhoea, psychological disturbances and vomiting
Fentanyl is slow to act but has a long half life.
Accumulation of morphine can result in coma
Buprenorphine and azathioprine are used in the treatment of terminal cancer pain
Questão 9
Questão
Select the cytotoxic agents
Responda
Calcium channel blockers
Antiarbitrucins
Antimetabolites
Alkylating agents
Hormonal agonists
Hormonal inhibitors
Questão 10
Questão
Chlorambucil and Carboplatin target the mechanism for cell division
Responda
True
False
Questão 11
Questão
The antiandrogenic drug Flutamide is administered to prostate cancer sufferers.
Responda
True
False
Questão 12
Questão
5-fluorouacil (5-FU) is an hormonal inhibitor that acts by blocking synthesis of pyramidine nucleotides
Responda
True
False
Questão 13
Questão
Side effects common to alkylating agents, antibiotic-type agents and antimetabolites include
Responda
Bone marrow suppression
GI disturbances
mouth ulcers
impaired fertility
bleeding
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