Neuropathology III - Raised ICP, SOL & Trauma

Description

Neuropathology III - Raised ICP, Space Occupying Lesions & Trauma lecture given in week 4
Matthew Coulson
Quiz by Matthew Coulson, updated more than 1 year ago
Matthew Coulson
Created by Matthew Coulson about 6 years ago
18
1

Resource summary

Question 1

Question
The normal ICP range is between 5-10mmHg. Anything over [blank_start]15[blank_end]mmHg is considered to be a high ICP
Answer
  • 15

Question 2

Question
[blank_start]Hydrocephalus[blank_end] is an accumulation of excessive CSF within the ventricular system of the brain.
Answer
  • Hydrocephalus

Question 3

Question
The normal volume of CSF is ...
Answer
  • 120-150ml
  • 100-130ml
  • 150-170ml
  • 150-250ml

Question 4

Question
As CSF travels from the 3rd to the 4th ventricle via the cerebral aqueduct, some can escape via two distinct foramen called ...
Answer
  • The foramen of Magendie
  • The foramen of Luschka
  • The foramen of Roberts
  • The foramen of Winslow
  • The foramen of Panizza

Question 5

Question
Types of Hydrocephalus: [blank_start]Communicating[blank_end] = Obstruction to CSF flow originates outside the ventricular system (e.g. subarachnoid space) [blank_start]Non-Communicating[blank_end] = Obstruction to CSF flow originates within the ventricular system
Answer
  • Communicating
  • Non-Communicating
  • Obstructive
  • Non-Obstructive

Question 6

Question
Raised ICP can cause coning of the brainstem, which leads to death due to ...
Answer
  • Lack of ability to breathe normally
  • Lack of ability to regulate heart rate (extreme bradycardia causes death)
  • Immunosuppression (death via infection)
  • Loss of downwards neurological controls

Question 7

Question
Temporal lobe uncal herniation typically leads to compression of which cranial nerve?
Answer
  • Oculomotor Nerve
  • Trigeminal Nerve
  • Facial Nerve
  • Glossopharyngeal Nerve
  • Vagus Nerve

Question 8

Question
In children, 70% of tumours arise below which structure? In adults, approximately 70% of tumours arise above this structure.
Answer
  • Tentorium Cerebelli
  • Diaphragm Sellae
  • Pons
  • Corpus Callosum
  • 3rd Ventricle

Question 9

Question
In both children and adults, the most common type of tumour is ...
Answer
  • Astrocytoma
  • Oligodendroglioma
  • Ependymoma
  • Meningioma
  • Schwannoma
  • Lymphoma

Question 10

Question
If an astrocytoma shows neovascularization, it is most likely to be a ...
Answer
  • Pilocytic Astrocytoma
  • Well Differentiated Astrocytoma
  • Anaplastic Astrocytoma
  • Glioblastoma

Question 11

Question
Which astrocytoma is the most common brain tumour in children?
Answer
  • Pilocytic astrocytoma
  • Well differentiated astrocytoma
  • Anaplastic astrocytoma
  • Glioblastoma Multiforme

Question 12

Question
The second most common brain tumour in children after pilocytic astrocytoma is ...
Answer
  • Medulloblastoma
  • Craniopharyngioma
  • Meningioma
  • Ependymoma

Question 13

Question
Is medulloblastoma more sensitive to chemo or radiotherapy?
Answer
  • Chemotherapy
  • Radiotherapy

Question 14

Question
This patient, who suffered from headaches and fever, is likely to have suffered which condition?
Answer
  • Multiple brain abscesses
  • Multiple brain metastases

Question 15

Question
Common causes of bacterial meningitis: [blank_start]E.coli[blank_end] = Neonates [blank_start]H.Influenzae[blank_end] = Infants & Children [blank_start]Neisseria Meningitidis[blank_end] = Adolescents & Young Adults [blank_start]Listeria Monocytogenes[blank_end] = Older Adults
Answer
  • E.coli
  • H.Influenzae
  • Neisseria Meningitidis
  • Listeria Monocytogenes

Question 16

Question
Coup & Contracoup Brain Injuries: [blank_start]Coup[blank_end] = Occurs to the brain on the side of the impact [blank_start]Contracoup[blank_end] = Occurs to the brain on the diametrically opposite point of impact [blank_start]Contracoup[blank_end] injuries are typically the more severe injuries.
Answer
  • Coup
  • Contracoup
  • Contracoup
  • Coup
  • Contracoup
  • Coup

Question 17

Question
Diffuse Axonal Injury is typically caused via [blank_start]blunt[blank_end] trauma to the head. This lesions typically affect the [blank_start]central[blank_end] structures of the brain and, if they don't cause immediate death, leads to multiple clusters of [blank_start]microglial[blank_end] cells throughout the white matter weeks after injury.
Answer
  • blunt
  • penetrative
  • central
  • peripheral
  • microglial
  • oligodendritic
  • astrocytic
  • neutrophilic
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