Healing in specalised tissues

Description

Medicine Quiz on Healing in specalised tissues, created by Laura Currie on 27/10/2018.
Laura Currie
Quiz by Laura Currie, updated more than 1 year ago
Laura Currie
Created by Laura Currie about 6 years ago
16
0

Resource summary

Question 1

Question
Granulation tissue appearance includes [blank_start]capillary sprouts[blank_end] from venular endothelium --> perpendicular to the wound surface, leaky ([blank_start]oedema[blank_end], [blank_start]exudate[blank_end] (protein rich). --> [blank_start]Fibroblasts[blank_end] growing in from sides and base of wound: makes collagen type 3 then 1, change phenotye to [blank_start]myofibroblast[blank_end] ( wound [blank_start]contraction[blank_end] ), hyaluronic acid and sulfated proteoglycans made.
Answer
  • capillary sprouts
  • oedema
  • exudate
  • Fibroblasts
  • myofibroblast
  • contraction

Question 2

Question
Bone fracture is a bone lesion which leads to bone discontinuity
Answer
  • True
  • False

Question 3

Question
Bone repair depends on; Type of [blank_start]break[blank_end] - Result of strength & direction of applied force --> [blank_start]axial[blank_end] force (compressional fracture), Torsion force ([blank_start]spiral[blank_end] fracture), Combined [blank_start]torsion[blank_end] and compressional force leads to an [blank_start]angel[blank_end] and displaced fracture Adjacent tissue damage effects [blank_start]rate[blank_end] of repair. (e.g muscles)
Answer
  • break
  • axial
  • spiral
  • torsion
  • angled
  • rate
  • growth
  • deterioration

Question 4

Question
which one of these are bone repair host factors?
Answer
  • Age, nutrition & overall health
  • Site of injury
  • immobilisation of fracture
  • degree of damage

Question 5

Question
healing of bone is triphasic
Answer
  • True
  • False

Question 6

Question
Healing of bone phases 1: [blank_start]Inflammatory phase[blank_end] 2: Reparative 3: [blank_start]Remodelling[blank_end]
Answer
  • Inflammatory phase
  • Remodelling

Question 7

Question
What would most likely to occur after 2 days of bone injury?
Answer
  • Blood clot formation
  • Ingrowth of capillary sprouts & fibroblasts from wound edge
  • Fibrocartilage formation
  • trabeculae of cancellous bone unite

Question 8

Question
Callus formation into chondrocytes is in remodelling phase of bone repair.
Answer
  • True
  • False

Question 9

Question
Bone Callus is a collar of [blank_start]osteogenic[blank_end] cells around a bone fracture. Has the same function as granulation tissue.
Answer
  • osteogenic

Question 10

Question
In the reparative phase (II) of bone repair, Trabeculae of [blank_start]cancellous[blank_end] bone slowly unite. There's [blank_start]capillary[blank_end] ingrowth from edge of marrow cavity. [blank_start]Osteoblasts[blank_end] differentiate, cancellous bone laid down. [blank_start]Fibrocartilage[blank_end] formed in less vascular areas. After long periods of time, [blank_start]osteoclasts[blank_end] start to remodel. Marrow slowly replaced.
Answer
  • cancellous
  • dense
  • capillary
  • veins
  • Osteoblasts
  • chondroblasts
  • Fibrocartilage
  • Hyaline cartilage
  • osteoclasts

Question 11

Question
In [blank_start]Remodelling[blank_end] phase (III) of bone repair, it may take years. Bone contours are re-organised and excess [blank_start]callus[blank_end] removed.
Answer
  • callus
  • scar tissue
  • Remodelling
  • Inflammatory
  • Reparative

Question 12

Question
What happens after weeks of bone repair?
Answer
  • Chondrocytes multiply
  • All cancellous bone converted of to lamellar bone
  • Chondrocytes mineralises & dies after callus is vascularised
  • It is the remodelling phase, callus is removed

Question 13

Question
Surgical incisions in bone --> healing with minimal [blank_start]callus[blank_end] formation and minimal disruption to the bone's ordered structure
Answer
  • callus

Question 14

Question
Neuronal cells are mitotic and can be replaced
Answer
  • True
  • False

Question 15

Question
What is Gliolisis?
Answer
  • Proliferation of neuroglia repairing damage
  • Glial cells dying off
  • Neurons proliferating
  • Dendrites proliferating

Question 16

Question
In PNS (Peripheral nervous system), nerve axons can be [blank_start]replaced[blank_end]. If Basement membrane of [blank_start]Schwann[blank_end] is disrupted, resorbed axons may miss each other resulting in a traumatic [blank_start]neuroma[blank_end]. If they are [blank_start]intact[blank_end], axonal growth has path to follow.
Answer
  • replaced
  • Schwann
  • myelin sheath
  • neuroma
  • neuroblastoma
  • carcinoma
  • intact
  • removed

Question 17

Question
When basement membrane is intact; (PNS)
Answer
  • Growth of axonal sprouts from surviving stumps begin at 4mm/day
  • There is no axonal sprout growth.
  • Myelin sheath breaks down around axonal tip

Question 18

Question
Tissue healing in liver - acute injury heals by complete regeneration, whilst chronic is usually leading to collapse of reticulin framework, along with surrounding by fibrosis also known as CIRRHOSIS.
Answer
  • True
  • False

Question 19

Question
Which one of these are correct in regards to tissue healing in kidneys?
Answer
  • Tubular epithelium can regenerate after damage
  • Glomeruli can regenerate - No scar tissue
  • Glomeruli cannot regenerate - Scar tissue formed

Question 20

Question
Metaplasia is a form of healing in epithelial surfaces
Answer
  • True
  • False

Question 21

Question
An example of metaplasia includes replacement of ciliated columnar epithelium to squamous type that is resistant to trauma in chronic smoking damaged individuals.
Answer
  • True
  • False

Question 22

Question
Cardiac muscle cells are permanent and does not regenerate. Repairs by fibrosis
Answer
  • True
  • False

Question 23

Question
Skeletal muscle has no ability of healing/regeneration at all.
Answer
  • True
  • False

Question 24

Question
Smooth muscle has limited regeneration - can regenerate if loss is minimal
Answer
  • True
  • False

Question 25

Question
Respiratory epithelium [blank_start]can[blank_end] regenerate. However, basement membrane must be intact and CT framework minimally disrupted. If basement membrane disrupted, [blank_start]fibrosis[blank_end] occurs.
Answer
  • can
  • cannot
  • fibrosis
  • inflammation

Question 26

Question
Which one(s) of these answers are true of cartilage healing?
Answer
  • Will replace itself by superficial ulceration if damage is small
  • Cannot replace itself
  • Extensive damage may have resultant haematoma following fibrosis
  • Undergoes aplastic changes

Question 27

Question
Regeneration is good in tendon healing
Answer
  • True
  • False
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