Copy and Edit

Pharmacology

Description

Quiz on Pharmacology , created by Berfin Miiau on 24/12/2018.
Berfin Miiau
Quiz by Berfin Miiau, updated more than 1 year ago
Berfin Miiau
Created by Berfin Miiau almost 6 years ago
48
0
0

Resource summary

Question 1

Question
the main routes of enteral administration of drugs are
Answer
  • oral
  • by injection
  • rectal
  • per mucosa

Question 2

Question
Advantages of the oral route of drug administration are
Answer
  • easily self-administered
  • toxicity and overdose may be overcome with antidotes
  • drugs avoid first-pass metabolism
  • drugs go directly into the systemic circulation

Question 3

Question
Advantages of the rectal route of drug administration are
Answer
  • suitable for vomiting patients
  • suitable for children
  • suitable for unconscious patients
  • a way to avoid first-pass metabolism

Question 4

Question
Disadvantages of iv drug administration are
Answer
  • a trained staff is required
  • risk of bacterial contamination at the site of injection
  • it is painful and stressful for the patient
  • drugs undergo first-pass metabolism in the liver

Question 5

Question
Point out the correct statements for iv drug administration
Answer
  • aqueous solutions can be administered iv
  • oil solutions can be administered iv
  • has the highest bioavailability
  • used for treatment of life-threatening conditions

Question 6

Question
The subject of pharmacokinetics is
Answer
  • drug absorption and distribution
  • drug biotransformation
  • drug elimination
  • drug biological activity

Question 7

Question
Point out the correct statements for passive diffusion
Answer
  • does not require energy
  • requires energy
  • involves a carrier
  • drugs move from high to lower concentration

Question 8

Question
The diffusion of lipid soluble drugs
Answer
  • depends on the charge of the drug molecule
  • does not depend on the charge of the drug molecule
  • is penetration through aqueous channels or pores
  • is penetration through the biological membranes

Question 9

Question
A drug-weak acid will be absorbed
Answer
  • in a medium with low pH
  • in a medium with high pH
  • in the stomach
  • in the intestine

Question 10

Question
A drug-weak base will be absorbed
Answer
  • in a medium with low pH
  • in a medium with high pH
  • in the stomach
  • in the intestine

Question 11

Question
Point out the correct statements for active drug transport
Answer
  • it is energy- dependent
  • it is not energy- dependent
  • requires carriers
  • does not require carriers

Question 12

Question
Point out the correct statement for drugs bound to plasma proteins
Answer
  • bound drugs are pharmacologically active
  • only the unbound drugs can act on target sites in the tissues
  • only the bound drugs are available to the process of elimination
  • drugs may displace each other from the binding proteins

Question 13

Question
Drug metabolism may
Answer
  • increase a drug's pharmacological activity
  • decrease a drug's pharmacological activity
  • change the pharmacological effects of a drug
  • change the toxicity of a drug

Question 14

Question
first phase liver metabolism reactions include
Answer
  • acetylation
  • conjugation
  • reduction
  • oxidation

Question 15

Question
Second phase liver metabolism reactions include
Answer
  • acetylation
  • conjugation
  • reduction
  • oxidation

Question 16

Question
Phase I of drug metabolism
Answer
  • may or may not involve cytochrome P450 system
  • phase I reactions convert lipophilic molecules to more polar molcecules
  • includes alcohol dehydrogenation, amine oxidation, hydrolysis
  • consists of conjugation reactions

Question 17

Question
Renal excretion of a drug will be reduced if
Answer
  • the drug is a weak acid and the urine is alkaline
  • the drug is a weak acid and the urine is acidic
  • the drug is a weak base and the urine is alkaline
  • the drug is a barbiturate and the urine is alkaline

Question 18

Question
Drug pharmacodynamics includes
Answer
  • drug effects
  • mechanisms of drug action
  • drug elimination
  • how the organism changes drugs

Question 19

Question
The changes that occur due to the interaction between drug molecules and organism structures are called
Answer
  • drug effect
  • drug action
  • adverse drug reaction
  • placebo effect

Question 20

Question
The organism response as a result of the changes that have occured due to its interaction with the drug is called
Answer
  • drug action
  • drug effect
  • adverse drug reaction
  • placebo effect

Question 21

Question
What is characteristic for a drug receptor
Answer
  • induces (generates) a change in organism functions
  • has selectivity
  • has sensitivity
  • has specifity

Question 22

Question
Agonists are ligands which
Answer
  • have affinity
  • block receptors
  • have intrinsic activity
  • bind to the receptor

Question 23

Question
Antagonists are ligands which
Answer
  • have strong affinity
  • have intrinsic activity
  • block the receptor
  • do not have intrinsic activity

Question 24

Question
Therapeutic margin is the
Answer
  • difference between maximal toxic and minimal therapeutic doses
  • ratio between minimal toxic and minimal therapeutic doses
  • difference between mean lethal and mean effective doses
  • ratio between lethal and mean effective doses

Question 25

Question
Drugs' therapeutic index is the
Answer
  • difference between minimal toxic and minimal therapeutic doses
  • ratio between minimal toxic and minimal therapeutic doses
  • difference between mean lethal and mean effective doses
  • ratio between mean lethal and mean effective doses

Question 26

Question
Types of drug interaction are
Answer
  • synergy
  • antagonism
  • synergy/ antagonism
  • chemical antagonism (formation of complexes)

Question 27

Question
Potentiation can be observed during the concomitant use of
Answer
  • Fentanyl and Droperidol
  • Heparin and Protamine
  • Amoxicillin and Clavulonic acid
  • Diazepam and Flumazenil

Question 28

Question
Full competitive antagonist of opioid receptors, administered in acute opioid intoxication is
Answer
  • Allylnormorphine
  • Methadone
  • Naloxone
  • Flumazenil

Question 29

Question
Chemical antagonism or complex formation can be observed in
Answer
  • Morphine and Naloxone
  • Diazepam and Flumazenil
  • Epinephrine and Histamine
  • Iron preparation and Deferroxamine

Question 30

Question
Which of the following are enzyme inducers
Answer
  • Phenytoin
  • Phenobarbital
  • Metamizol
  • Metronidazole

Question 31

Question
Multiple drug administration could lead to
Answer
  • drug tolerance
  • drug dependence
  • drug accumulation
  • allergic reactions

Question 32

Question
Drug addicition/ dependence involves
Answer
  • drug tolerance
  • physical dependence
  • psychological dependence
  • allergy

Question 33

Question
Antiseptics are used for
Answer
  • decontamination of laundry and sanitary facilities
  • decontamination of skin and mucous membranes
  • internal administration
  • treatment of fever

Question 34

Question
Disinfectants are used for decontamination of
Answer
  • urine, faeces and other
  • mouth
  • instruments
  • clothing and underwear

Question 35

Question
Antiseptics and disinfectants are
Answer
  • detergents
  • barbiturates
  • oxidizing agents and halogen derivatives
  • phenols
Show full summary Hide full summary

Want to create your own Quizzes for free with GoConqr? Learn more.

Similar

Testumfrage für Lipomed
Olli L.
Clinical Pathology MCQs
Berfin Miiau
Pharmacology MCQs- 4th Year- PMU
Berfin Miiau
Pharma MCQs- 4th Year- Corrected
Berfin Miiau
Pharmakologie
Simon Baur
The Rock Cycle
eimearkelly3
10 Study Techniques
PatrickNoonan
AQA Biology B2 Questions
Bella Statham
Biology B1
Phoebe Drew
Mind Maps with GoConqr
Elysa Din
Cloud Data Integration Specialist Certification
James McLean
Browse Library