Question 1
Question
There is a decreased absorption of [blank_start]acidic[blank_end] drugs such as phenytoin, aspirin and penicillins in elderly patients due to an increasingly [blank_start]alkaline[blank_end] gastric pH
Answer
-
alkaline
-
acidic
-
acidic
-
alkaline
Question 2
Question
Elderly people have a [blank_start]higher[blank_end] volume of distribution of lipophilic drugs than the general population.
Question 3
Question
Grapefruit Juice, in theory, causes myalgia in patients who take which of the following medication types?
Answer
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Statins
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Antimuscarinics
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Calcium Channel Blockers
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Beta Blockers
-
ACE Inhibitors
Question 4
Question
Cranberry juice is known to lower a patient's INR, thus making thromboembolism more likely.
Question 5
Question
The end of a human chromosome, which progressively shortens within each cell replication, is called the [blank_start]telomere[blank_end]
Question 6
Question
In humans, a telomere consists of multiple repeats of which single motif:
Answer
-
TTAGGG
-
AATCCC
-
CCGTTT
-
GCCAAA
Question 7
Question
Relating to telomeres, the [blank_start]Hayflick[blank_end] limit is the number of times a normal human cell population will divide before cell division stops
Question 8
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Sepsis in elderly patients usually presents with [blank_start]a decreased[blank_end] temperature
Question 9
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Delirium typically has a [blank_start]fluctuating[blank_end] course
Question 10
Question
[blank_start]Hypoactive[blank_end] delirium has twice the mortality rate of [blank_start]hyperactive[blank_end] delirium
Answer
-
hyperactive
-
hypoactive
-
Hypoactive
-
hyperactive
Question 11
Question
In terms of the 4AT score:
In terms of Alertness, a patient who has mild sleepiness for <10s after waking then is normal receives which score?
Question 12
Question
In terms of the 4AT score:
A patient whose alertness is judged to be 'clearly abnormal' would receive a score of ...
Question 13
Question
In terms of the 4AT score:
After Alertness, the second part of the 4AT score assesses AMT4, which involves the patient stating their age, DOB, where they are and the current year.
No mistakes warrants a score of [blank_start]0[blank_end]
1 mistake warrants a score of [blank_start]1[blank_end]
2 or more mistakes warrants a score of [blank_start]2[blank_end]
Question 14
Question
In terms of the 4AT score:
After assessing 4AT, the patient has their attention span assessed. In order to do this, the patient is asked to name the months of the year backwards from December.
Achieves 7 months or more correctly = [blank_start]0[blank_end]
Starts but scores <7 months/refuses to start = [blank_start]1[blank_end]
Untestable (too unwell, too drowsy, etc) = [blank_start]2[blank_end]
Question 15
Question
In terms of the 4AT score:
After testing attention, the last parameter which is tested is the presence of an acute or fluctuating course (i.e. evidence of significant change or fluctuation in alertness, cognition, etc)
A fluctuating course warrants a score of [blank_start]4[blank_end]
Question 16
Question
The maximum score a patient can get for the 4AT is
Question 17
Question
In delirious patients, which medication is first line for sedation if it is needed (e.g. if patient is psychotic or refusing to stay in bed)?
[blank_start]Haloperidol[blank_end]
Question 18
Question
For sedation of delirious patients, Haloperidol should be given intramuscularly.
Question 19
Question
Delirium is a risk factor for developing dementia
Question 20
Question
Age related loss of muscle mass and function is called [blank_start]sarcopenia[blank_end]
Question 21
Question
Muscle mass starts to decline as of age [blank_start]30[blank_end]
Question 22
Question
The suggested target for physical activity in the elderly population (65+) is the same as it is for the adult population (18-64)
Question 23
Question
Weekly Physical Activity Guidelines for Adults (18-64) and Elderly (65+):
[blank_start]150[blank_end] minutes of moderate intensity activity
OR
[blank_start]75[blank_end] minutes of vigorous intensity activity
Strength and balance work should also be included at least [blank_start]2[blank_end] times per week
Question 24
Question
Which of the following has been shown to increase muscle function associated with sarcopenia in elderly patients?
Answer
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Beta Blockers
-
ACE Inhibitors
-
Calcium Channel Blockers
-
Dopamine Agonists
-
Levothyroxine
Question 25
Question
When stepping up a patient from codeine to morphine for analgesia, the following must be considered:
10mg of Codeine is equivalent to [blank_start]1[blank_end]mg of morphine.
Question 26
Question
In order to convert the dosage of MST Morphine to the equivalent dosage of Oramorph, you divide the former by [blank_start]6[blank_end].
For example, a patient on 60mg of MST would take [blank_start]10[blank_end]mg of Oramorph to have the same effect.
Question 27
Question
Smoothest delivery of medicines in palliative care patients is via a continuous subcutaneous infusion using a [blank_start]syringe[blank_end] driver
Question 28
Question
In terms of using Syringe Drivers to administer medications in the elderly, how many different medicines can be mixed together in one syringe?
Question 29
Question
Morphine is [blank_start]two times[blank_end] as potent when given subcutaneously (as opposed to oral administration)
Answer
-
two times
-
three times
-
half
Question 30
Question
Arrange the steps of pharmacokinetics in order starting with the point the drug enters the body.
[blank_start]Absorption[blank_end]
[blank_start]Distribution[blank_end]
[blank_start]Metabolism[blank_end]
[blank_start]Excretion[blank_end]
Answer
-
Absorption
-
Metabolism
-
Excretion
-
Distribution
Question 31
Question
Elderly people typically have a [blank_start]decreased[blank_end] small bowel surface area
Question 32
Question
Protein binding of drugs:
[blank_start]Albumin[blank_end] binds to Acidic Drugs
[blank_start]Alpha-1 Acid Glycoprotein[blank_end] binds to Alkaline Drugs
Question 33
Question
Elderly patients typically have [blank_start]decreased[blank_end] albumin levels and [blank_start]increased[blank_end] alpha-1 acid glycoprotein levels
Answer
-
increased
-
decreased
-
decreased
-
increased
Question 34
Question
Elderly patients typically have a [blank_start]decreased[blank_end] body water level.
Question 35
Question
Very importantly, the Volume of Distribution of Hydrophilic drugs (lithium, digoxin, etc) in elderly patients is [blank_start]decreased[blank_end].
Question 36
Question
It is generally accepted that higher doses of medications are needed to achieve the same effects in the elderly population.
Question 37
Question
Which of the following minerals interferes with levothyroxine
Question 38
Question
Verapamil (CCB) should never been given with which drug type, for fear of causing symptomatic heart block?
Answer
-
Beta Blocker
-
Statins
-
Anticonvulsants
-
Thiazide Diuretics