1835988
Question 1
Question
All cells have the same genes. True or false?
Answer
- True
- False
Question 2
Question
Which of these are examples of house-keeping genes?
Answer
-
Glycolysis enzymes
-
DNA polymerase
-
Genes that code for haemoglobin
-
Genes that code for melanin
-
Genes that code for the cytoskeleton
Question 3
Question
What are the types of transcript?
Answer
-
Abundant transcript
-
Rare transcript
-
No transcript
-
Positive transcript
-
Negative transcript
Question 4
Question
To what level are house-keeping genes normally transcribed?
Answer
-
Abundant transcript
-
Rare transcript
-
No transcript
Question 5
Question
When might genes that usually have no transcript be transcribed?
Answer
-
During development
-
In response to a stimuli
-
In disease states
Question 6
Question
The amount that genes are transcribed cannot be altered. True or false?
Answer
- True
- False
Question 7
Question
What are transcription factors?
Answer
-
Proteins that bind to DNA to prevent or allow transcription to occur
-
Proteins that bind to DNA and unwind it initiating transcription
-
Proteins that bind to RNA polymerase making it more efficient
Question 8
Question
What two transcription factors are present in the Lac Operon?
Answer
-
CAP Protein
-
Lac represser
-
Lac ZYA
-
TATA proteins
Question 9
Question
Where do transcription factors bind to in eukaryotes?
Answer
-
The major groove in DNA
-
The minor groove in DNA
-
The promoter
-
The telomere
Question 10
Question
Why do transcription factors bind to the major groove?
Answer
-
The base pairs are not exposed in the minor groove
-
There are more binding sites in the major groove
-
The major groove is more recognizable
-
There is not enough room in the minor groove
Question 11
Question
Transcription factors have to unwind DNA to find their binding point. True or false?
Answer
- True
- False
Question 12
Question
What are TATA boxes?
Answer
-
A part of DNA made up of many thymines and adenines which act as a binding site for transcription factors
-
An area of DNA where thymine and adenine alternate for more then 100 base pairs to signal the end of an intron
-
An area of DNA where thymines and adenines are added gradually throughout life that scientists use to estimate the age of someone
Question 13
Question
What transcription factor binds to TATA boxes?
Answer
-
TBP
-
Lac ZYA
-
CAP protein
Question 14
Question
What are regulatory elements?
Answer
-
Specific patterns that are recognized by regulatory factors
-
Generic patterns that are recognized by a variety of regulatory factors
-
Palindromic patterns in DNA that are recognized by regulatory factors
Question 15
Question
In eukaryotes, often it requires many transcription factors to lead to transcription. True or false?
Answer
- True
- False
Question 16
Question
Are histones positively or negatively charged?
Answer
-
Positively
-
Negatively
Question 17
Question
Why do histones need to positively charged?
Answer
-
So they can bind to DNA
-
So they can move through the nuclear membrane
-
So they can move through the cell membrane
-
So they don't interact with protein synthesis
Question 18
Question
How do transcription factors make histones disassociate from DNA?
Answer
-
They acetylate them so there is no positive charge
-
They give DNA in that area a neutral charge so the histones can no longer bind to it
-
They add chloride ions to the histones to make them negatively charged
Question 19
Question
Why is it necessary to disassociate the histones from DNA?
Answer
-
So that transcription can occur
-
So DNA can be replicated
-
So that DNA can coil up tight enough to fit within the nucleus of the cell
-
To allow DNA to be studied under a microscope
-
To allow DNA to form its double helix shape
Question 20
Question
The less differentiated a cell is the more likely it is able to go back to its undifferentiated state. True or false?
Answer
- True
- False
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