3931332
Description
Quiz by chris.kingsnorth, updated more than 1 year ago
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Created by chris.kingsnorth
about 9 years ago
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Question 1
Question
How many children are affected by CF in the UK?
Answer
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1 in 25,000
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1 in 2500
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1 in 250
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1 in 250,000
Question 2
Question
How many people are carriers of CF in the UK?
Answer
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1 in 25
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1 in 250
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1 in 25,000
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1 in 250,000
Question 3
Question
Inheritance of CF is autosomal dominant
Answer
- True
- False
Question 4
Question
∆F508 is the most common CF mutation
Answer
- True
- False
Question 5
Question
The defective protein in CF is called:
Answer
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CFTR
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CTFR
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CRTF
Question 6
Question
In the most common mutation of CFTR, the protein can escape the ER but once in the cell membrane dose not function properly
Answer
- True
- False
Question 7
Question
Positive Guthrie testing for CF is diagnostic of the condition
Answer
- True
- False
Question 8
Question
Low Na concentration in sweat on sweat test suggests CF
Answer
- True
- False
Question 9
Question
Growth of patients with CF is unaffected
Answer
- True
- False
Question 10
Question
Clinical features of CF are similar in all patients
Answer
- True
- False
Question 11
Question
Which of the following medications are not used in treatment of CF?
Answer
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Bronchodilators (e.g. salmeterol)
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Anticholinergics (e.g. ipratropium)
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Antibiotics
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Steroids
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Mucolytics (e.g. DNase)
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Beta-blockers
Question 12
Question
CFTR modulators are currently the mainstay of treatment for CF in the UK
Answer
- True
- False
Question 13
Question
Median survival in CF is currently estimated at:
Answer
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31 years
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41 years
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51 years
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61 years
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