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Atherogenesis

Description

Year 2 (Lipid Deficiencies) Quiz on Atherogenesis, created by gina_evans0312 on 15/02/2014.
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Quiz by gina_evans0312, updated more than 1 year ago
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Created by gina_evans0312 almost 11 years ago
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Resource summary

Question 1

Question
What is an Atheroma?
Answer
  • Artifical thickening of arterial cell walls that excludes a thick lipid mix
  • Artificial coarsening of arterial cell walls that shed bacteria into the bloodstram
  • Bacterial biofilm forming over the cell wall

Question 2

Question
What causes the Endothelial Dysfunction that begins atheroma growth?
Answer
  • Cigarette smoke
  • Excess LDL's
  • Bacterial infection
  • Autoimmune disorders
  • Diabetes

Question 3

Question
What happens to epithelial cells during Endothelial Dysfunction?
Answer
  • They become lipoprotein soluble and lose cell repellant quality
  • They become lipoprotein inoluble and gain cell repellant quality
  • They become lipoprotein soluble and gain cell repellant quality

Question 4

Question
VCAM- A monocyte adhesion molecule that allows them to enter the vascular wall
Answer
  • True
  • False

Question 5

Question
Once monocytes convert to macrophages in tissue, what do they produce?
Answer
  • ROS
  • Acids
  • Bases

Question 6

Question
During Lipid Deposition, lipids can easily enter the damaged endothelial walls
Answer
  • True
  • False

Question 7

Question
What happens to LDL's once they enter the tissue
Answer
  • They're oxidied by macrophages
  • They're reduced by macrophages

Question 8

Question
LDLs are so easily reduced due to low tissue antioxidants
Answer
  • True
  • False

Question 9

Question
What happens when Macrophages take up too many LDL's?
Answer
  • They become dying Foam cells
  • They become dying Plasma cells
  • They become dying Mast cels

Question 10

Question
As the macrophages die, the release lipid pools
Answer
  • True
  • False

Question 11

Question
Name the two main components of the plaque?
Answer
  • Foam cells
  • Lipid pools
  • LDLs
  • Mast cells
  • Plasma cells

Question 12

Question
Vascular cells form a fibrous cap over the developing clot
Answer
  • True
  • False

Question 13

Question
What, potentially can happen to the fibrous plaque coat?
Answer
  • It calcifies and fissures at the edges
  • It becomes layered with t-cells and macrophages
  • Bacteria stick to it and invade tissues

Question 14

Question
Name the effect of arterial plaques
Answer
  • Blood flow decreases
  • Blood pressure rises
  • Blood flow increases
  • Plaque forces artery to widen
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