Quiz
L33 Pancreatic islets, insulin, glucagon, and diabetes
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Questions in this quiz (19)
1Which statement best describes the location of the pancreas?
- AThe pancreas sits under the larynx on the anterior of the trachea.
- BThe pancreas sits in the abdominal cavity.
- CThe pancreas sits in the C-shaped curve of the duodenum, with it's body extending behind the stomach.
2The pancreas is:
- Aan exocrine gland
- Ban endocrine gland
- Cboth an exocrine and endocrine gland.
3The majority of the pancreas secretes digestive enzymes.
- ATrue
- BFalse
4(Choose all correct options.)
Pancreatic islets:- Amake up 2% of the pancreas' mass
- Bhave 4 types of cells
- Chave alpha cells which secrete insulin
- Dhave beta cells which secrete glucagon
- Eare up to 1 million in number within the pancreas
5The reference range for blood glucose is between:
- A3.5 - 8 mmol/L
- B3.5 - 6 mmol/L
- C4 - 6 mmol/L
- D5 - 10 mmol/L
6Glucose is the only fuel the brain can use.
- ATrue
- BFalse
7During the day, fuel use ([blank_start]metabolism[blank_end]) is [blank_start]continuous[blank_end], but we only eat periodically. Hence, our blood glucose level [blank_start]changes[blank_end] throughout the day. We describe the two metabolic [blank_start]states[blank_end] the body moves between as the fed state and the fasting state.
In the fed state there is [blank_start]uptake[blank_end] of nutrients and [blank_start]anabolic[blank_end] metabolism taking place([blank_start]synthesis[blank_end] of glycogen, protein and fat).
Vice versa, in the fasting state there is [blank_start]mobilisation[blank_end] of nutrients and [blank_start]catabolic[blank_end] metabolism taking place([blank_start]breakdown[blank_end] of glycogen, protein and fat.)- Ametabolism
- Bcontinuous
- Cchanges
- Dstates
- Euptake
- Fanabolic
- Gsynthesis
- Hmobilisation
- Icatabolic
- Jbreakdown
8Choose the correct statements about insulin secretion.
- AInsulin is secreted by beta cells when blood glucose concentration increases above the reference range.
- BInsulin release can be a negative-feedback pathway or a feed-forward pathway.
- CCarbohydrates being broken down into glucose during digestion triggers insulin release.
- DTarget cells include everything but muscle and adipose tissue.
- EThe beta cells are the sensor and integrator of the system.
- FInsulin is a lipid-soluble hormone with an intracellular receptor.
9Which of these is not a symptom of Type I Diabetes?
- AHypoglycemia
- BPolyuria
- CPolydipsia
- DPolyphagia
10Insulin is the only hormone that can decrease blood glucose levels.
- ATrue
- BFalse
11Type I Diabetes is an autoimmune disease where insulin-producing alpha cells have been destroyed.
- ATrue
- BFalse
12The first treatments of insulin were on diabetic dogs. The first treatments of insulin to people were of crude insulin attained from bovine pancreases.
- ATrue
- BFalse
13Pure insulin can now be produced in vitro.
- ATrue
- BFalse
14Choose the incorrect statement about Type 2 Diabetes.
- A90% of Diabetes cases are Type 2.
- BIt is becoming more prevalent in children.
- CCells are resistant to insulin.
- DRisk factors for Type 2 are unknown.
- ELifestyle changes can be used to treat Type 2.
15(Choose all correct.)
Hyperglycemia can cause:- AAtherosclerosis (leading to heart attack, stroke)
- BKidney Disease
- CNerve Damage
- DBlindness
- EMuscular hypertrophy
- FPulmonary Edema
16Glucagon is a peptide hormone with intracellular receptors.
- ATrue
- BFalse
17Glucagon causes an increase in glucose and ketone synthesis.
- ATrue
- BFalse
18Glucagon causes a breakdown of glycogen.
- ATrue
- BFalse
19[blank_start]Gluconeogenesis[blank_end] is the synthesis of glucose, while [blank_start]glycogenolysis[blank_end] is the breakdown of [blank_start]glycogen[blank_end]. Both are stimulated by [blank_start]glucagon[blank_end].
- AGluconeogenesis
- Bglycogenolysis
- Cglucagon
- Dglycogen
Information
- Description
- • Describe the structure and location of the pancreatic islets. • Outline the sequence of events that occurs when blood glucose concentration increases above or decreases below the reference range • Describe the effects of insulin on each type of target cell. • Compare the role of insulin and glucagon in the control of blood glucose concentration in the fed state and the fasting state. • Explain what diabetes mellitus is and distinguish between type 1 diabetes and type 2 diabetes.
- Author
- Mer Scott
- Language
- English
- Views
- 58
- History
- Created on 15 May 2017 · updated on 6 Apr 2018
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