Zusammenfassung der Ressource
Frage 1
Frage
[blank_start]__________[blank_end] serum Calcium – sensed by Calcium-sensing Receptor (CaR) in the [blank_start]__________[blank_end] triggers release of PTH.
Antworten
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Decreased
-
Increased
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ParaThyroid Gland
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Hypothalamus
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Thyroid Gland
Frage 2
Frage
In response to decreased serum Calcium, PTH is released and goes to which of the following?
Antworten
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Kidney
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Bone
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Gut
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Muscle
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Liver
Frage 3
Frage
In the kidney, what PTH has 3 effects. These are:
a: [blank_start]_____[blank_end] 1,25 (OH)2 D;
b: [blank_start]_____[blank_end] Ca reabsorption;
c: [blank_start]_____[blank_end] PO4 reabsorption;
Antworten
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Increase
-
Decrease
-
Increase
-
Decrease
-
Increase
-
Decrease
Frage 4
Frage
In the bone, PTH has 2 effects. These are:
a: ↑ [blank_start]__________[blank_end];
b: ↑ Bone [blank_start]__________[blank_end] (releasing Ca).
Antworten
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Osteoclasts
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Osteoblasts
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Osteocytes
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Lining Cells
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Resorption
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Formation
Frage 5
Frage
PTH-1 is a class-B GPCR. Yeah?
Frage 6
Frage
The primary effect of Hyperparathyroidism is:
Antworten
-
Increase blood Ca
-
Decrease blood Ca
-
Increase kidney Ca
-
Decrease kidney Ca
Frage 7
Frage
PROLONGED increase of PTH results in which of the following:
Frage 8
Frage
The main effect of INTERMITTENT PTH is:
Antworten
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Increased osteoblast numbers
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Increased osteoclast numbers
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Decreased osteoblast numbers
-
Decreased osteoclast numbers
Frage 9
Frage
True or false: Intermittent PTH has little effect on osteoclasts, although they are necessary for its action.
Frage 10
Frage
Sclerostin is a [blank_start]__________[blank_end] regulator of bone formation.
Frage 11
Frage
Mutations that inactivate Sclerostin cause [blank_start]__________[blank_end] bone mass.
Frage 12
Frage
Sclerostin is produced by which of the following:
Antworten
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Osteocytes
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Osteoclasts
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Osteoblasts
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Lining Cells
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PTH
Frage 13
Frage
Intermittent PTH [blank_start]__________[blank_end] sclerostin. Sclerostin [blank_start]__________[blank_end] Wnt signaling. Therefore Intermittent PTH has a [blank_start]__________[blank_end] effect on Wnt signalling and results in [blank_start]__________[blank_end] bone formation (and [blank_start]__________[blank_end] bone resorption).
Antworten
-
Decreases
-
Increases
-
Inhibits
-
Stimulates
-
Positive
-
Negative
-
Increased
-
Decreased
-
Decreased
-
Increased