16366412
Beschreibung
Quiz von Berfin Miiau, aktualisiert more than 1 year ago
|
Erstellt von Berfin Miiau
vor etwa 6 Jahre
|
|
Frage 1
Frage
the main routes of enteral administration of drugs are
Antworten
-
oral
-
by injection
-
rectal
-
per mucosa
Frage 2
Frage
Advantages of the oral route of drug administration are
Antworten
-
easily self-administered
-
toxicity and overdose may be overcome with antidotes
-
drugs avoid first-pass metabolism
-
drugs go directly into the systemic circulation
Frage 3
Frage
Advantages of the rectal route of drug administration are
Antworten
-
suitable for vomiting patients
-
suitable for children
-
suitable for unconscious patients
-
a way to avoid first-pass metabolism
Frage 4
Frage
Disadvantages of iv drug administration are
Antworten
-
a trained staff is required
-
risk of bacterial contamination at the site of injection
-
it is painful and stressful for the patient
-
drugs undergo first-pass metabolism in the liver
Frage 5
Frage
Point out the correct statements for iv drug administration
Antworten
-
aqueous solutions can be administered iv
-
oil solutions can be administered iv
-
has the highest bioavailability
-
used for treatment of life-threatening conditions
Frage 6
Frage
The subject of pharmacokinetics is
Antworten
-
drug absorption and distribution
-
drug biotransformation
-
drug elimination
-
drug biological activity
Frage 7
Frage
Point out the correct statements for passive diffusion
Antworten
-
does not require energy
-
requires energy
-
involves a carrier
-
drugs move from high to lower concentration
Frage 8
Frage
The diffusion of lipid soluble drugs
Antworten
-
depends on the charge of the drug molecule
-
does not depend on the charge of the drug molecule
-
is penetration through aqueous channels or pores
-
is penetration through the biological membranes
Frage 9
Frage
A drug-weak acid will be absorbed
Antworten
-
in a medium with low pH
-
in a medium with high pH
-
in the stomach
-
in the intestine
Frage 10
Frage
A drug-weak base will be absorbed
Antworten
-
in a medium with low pH
-
in a medium with high pH
-
in the stomach
-
in the intestine
Frage 11
Frage
Point out the correct statements for active drug transport
Antworten
-
it is energy- dependent
-
it is not energy- dependent
-
requires carriers
-
does not require carriers
Frage 12
Frage
Point out the correct statement for drugs bound to plasma proteins
Antworten
-
bound drugs are pharmacologically active
-
only the unbound drugs can act on target sites in the tissues
-
only the bound drugs are available to the process of elimination
-
drugs may displace each other from the binding proteins
Frage 13
Frage
Drug metabolism may
Antworten
-
increase a drug's pharmacological activity
-
decrease a drug's pharmacological activity
-
change the pharmacological effects of a drug
-
change the toxicity of a drug
Frage 14
Frage
first phase liver metabolism reactions include
Antworten
-
acetylation
-
conjugation
-
reduction
-
oxidation
Frage 15
Frage
Second phase liver metabolism reactions include
Antworten
-
acetylation
-
conjugation
-
reduction
-
oxidation
Frage 16
Frage
Phase I of drug metabolism
Antworten
-
may or may not involve cytochrome P450 system
-
phase I reactions convert lipophilic molecules to more polar molcecules
-
includes alcohol dehydrogenation, amine oxidation, hydrolysis
-
consists of conjugation reactions
Frage 17
Frage
Renal excretion of a drug will be reduced if
Antworten
-
the drug is a weak acid and the urine is alkaline
-
the drug is a weak acid and the urine is acidic
-
the drug is a weak base and the urine is alkaline
-
the drug is a barbiturate and the urine is alkaline
Frage 18
Frage
Drug pharmacodynamics includes
Antworten
-
drug effects
-
mechanisms of drug action
-
drug elimination
-
how the organism changes drugs
Frage 19
Frage
The changes that occur due to the interaction between drug molecules and organism structures are called
Antworten
-
drug effect
-
drug action
-
adverse drug reaction
-
placebo effect
Frage 20
Frage
The organism response as a result of the changes that have occured due to its interaction with the drug is called
Antworten
-
drug action
-
drug effect
-
adverse drug reaction
-
placebo effect
Frage 21
Frage
What is characteristic for a drug receptor
Antworten
-
induces (generates) a change in organism functions
-
has selectivity
-
has sensitivity
-
has specifity
Frage 22
Frage
Agonists are ligands which
Antworten
-
have affinity
-
block receptors
-
have intrinsic activity
-
bind to the receptor
Frage 23
Frage
Antagonists are ligands which
Antworten
-
have strong affinity
-
have intrinsic activity
-
block the receptor
-
do not have intrinsic activity
Frage 24
Frage
Therapeutic margin is the
Antworten
-
difference between maximal toxic and minimal therapeutic doses
-
ratio between minimal toxic and minimal therapeutic doses
-
difference between mean lethal and mean effective doses
-
ratio between lethal and mean effective doses
Frage 25
Frage
Drugs' therapeutic index is the
Antworten
-
difference between minimal toxic and minimal therapeutic doses
-
ratio between minimal toxic and minimal therapeutic doses
-
difference between mean lethal and mean effective doses
-
ratio between mean lethal and mean effective doses
Frage 26
Frage
Types of drug interaction are
Antworten
-
synergy
-
antagonism
-
synergy/ antagonism
-
chemical antagonism (formation of complexes)
Frage 27
Frage
Potentiation can be observed during the concomitant use of
Antworten
-
Fentanyl and Droperidol
-
Heparin and Protamine
-
Amoxicillin and Clavulonic acid
-
Diazepam and Flumazenil
Frage 28
Frage
Full competitive antagonist of opioid receptors, administered in acute opioid intoxication is
Antworten
-
Allylnormorphine
-
Methadone
-
Naloxone
-
Flumazenil
Frage 29
Frage
Chemical antagonism or complex formation can be observed in
Antworten
-
Morphine and Naloxone
-
Diazepam and Flumazenil
-
Epinephrine and Histamine
-
Iron preparation and Deferroxamine
Frage 30
Frage
Which of the following are enzyme inducers
Antworten
-
Phenytoin
-
Phenobarbital
-
Metamizol
-
Metronidazole
Frage 31
Frage
Multiple drug administration could lead to
Antworten
-
drug tolerance
-
drug dependence
-
drug accumulation
-
allergic reactions
Frage 32
Frage
Drug addicition/ dependence involves
Antworten
-
drug tolerance
-
physical dependence
-
psychological dependence
-
allergy
Frage 33
Frage
Antiseptics are used for
Antworten
-
decontamination of laundry and sanitary facilities
-
decontamination of skin and mucous membranes
-
internal administration
-
treatment of fever
Frage 34
Frage
Disinfectants are used for decontamination of
Antworten
-
urine, faeces and other
-
mouth
-
instruments
-
clothing and underwear
Frage 35
Frage
Antiseptics and disinfectants are
Antworten
-
detergents
-
barbiturates
-
oxidizing agents and halogen derivatives
-
phenols
Möchten Sie mit GoConqr kostenlos Ihre eigenen Quiz erstellen? eigenen Mehr erfahren.