Tyrosine Kinase

Beschreibung

Year 2 Quiz am Tyrosine Kinase, erstellt von gina_evans0312 am 02/12/2013.
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Quiz von gina_evans0312, aktualisiert more than 1 year ago
gina_evans0312
Erstellt von gina_evans0312 vor fast 11 Jahre
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Zusammenfassung der Ressource

Frage 1

Frage
When the ligand has bound, what moleucle forms?
Antworten
  • A homodimer
  • A heterodimer within the T.K family
  • A heterotrimer within the T.K family
  • A homotrimer

Frage 2

Frage
What is found in the active site that inhibits activity?
Antworten
  • A pseudosubstrate
  • An activation lip
  • A hydrophobic core that must be exposed

Frage 3

Frage
How do you activate the active site?
Antworten
  • Phosphorylation
  • Acetylation
  • Methylation

Frage 4

Frage
Which residues of tyrosine kinase are modified?
Antworten
  • Tyrosine
  • Serine
  • Threonine

Frage 5

Frage
What domain is required to bind to an activated Tyrosine Kinase?
Antworten
  • Sh2
  • Sh4
  • SH3

Frage 6

Frage
How large is an SH2 domain?
Antworten
  • 100 residues
  • 50 residues
  • 25 residues

Frage 7

Frage
How many pockets are there in SH2?
Antworten
  • 1
  • 2
  • 3

Frage 8

Frage
How does a specific molecule know where to dock on a tyrosine kinase receptor?
Antworten
  • The sequence of aa around the modification it binds to
  • The shape of the protein around the modification it binds to
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