Physiology Exam 1 : Homeostasis

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Exam 1 part 1
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Frage Antworten
The dynamic constansy of the internal environment of the human body. Homeostasis
________ tissue detects/measures actual value of a ________ and compares it to setpoint. Monitoring tissue; parameter
Monitoring tissue that is sensative to changes. Parameter
Normal _________ or level for body to be in homeostasis setpoint
A changes from the normal setpoint is a ______. Stimulus
_________ generate a response to the change caused by stimulus. Effector
The direction of the response is opposite to the direction of the stimulus Negative feedback loop
Response is in the same direction of the stimulus. Typically shortlived and must be terminated after completing their task. Positive feedback loop
Low blood pressure results in release of _________ by _____________ cells of the kidney nephrons. renin by juxtaglomerular cells
Renin (protein enzyme) cleaves ___________ (made by the liver) into ___________ (10 amino acids) angiotensinogen (made by the liver) into angiotensin I (10 amino acids)
Angiotensin I is cleaved into the 8 amino acid containing ___________ by ______________ in the blood vessels of the lungs. angiotensin II by angiotensin converting enzymes (ACE)
_____________ stimulates thirst and drinking (increasing blood volume and therfore blood pressure), causes vasoconstriction (increasing resistance and therfore increasing blood pressure), and stimulates the adrenal glands to release __________. Angiotensin II stimulates thirst and drinking... the adrenal glands to release aldosterone.
____________ travels to kidneys through the bloodstream and stimulates the nephron to actively secrete _________ into the urine but to reabsorb sodium and water into the bloodstream, increasing blood volume and therefore blood pressure. Aldosterone travels to kidneys .... actively secrete potassium ions (K+) into the urine
Absorption of glucose (hyperglycemia) results in the release of _____________. Glucose-dependent insulinotropic peptide (GIP)
___________ in the duodenum release GIP into the blood stream. Enteroendocrine cells
GIP goes through the blood stream to the __________ and along with high levels of glucose in the bloodstream stimulates the ________ to release ___________. islets of Langerhans of the pancreas; beta-cells to release insulin.
Insulin attaches to receptors on _____, ______ and _________ cells. hepatocytes, myocytes, and adipose cells.
Cells are stimulated to place ___________ into their membranes which permit glucose to be absorbed by diffuision (reducing blood sugar lever down to setpoint) GLUT proteins
Glucose is converted into __________ in liver and muscles cells and ________ in adipose cells. glycogen; fat (triglycerides)
When blood sugar levels are reduced below setpoint (hypoglycemia) ______ cells of the islets of Langerhans release _______. Alpha cells release glucagon.
Glucagon stimulates ___________. gluconeogenesis: the prodcution of glucose from noncarbohydrate molecules, including lactic acid and amino acids, primarily in the liver.
Glucagon also stimulates the breakdown of _____ into ______ which is released into the blood stream and which elevates blood sugar up to setpoint. Glycogen into glucose
GLUT proteins: __________ used by most cells of body, including brain, erythrocytes, endothelial and fetal tissues. GLUT 1
__________ used by liver cells, pancreatic beta cells, small intestines and kidneys; function when blood glucose levels high GLUT 2
___________ neurons, placenta and testes GLUT 3
_______ used by skeletal and cardiac muscle and adipose tissues; insulin-responsive glucose transporters; insulin stimulates _________ containing vessicles to move to membrane and allow cells to absorb glucose. GLUT 4
When a blood vessel is severed, blood leaks into connective tissue and _______ encounters collagen and stimulates platelets to stick to collagen; platelets release ______ and ________. vonWillebrand's Factor; platelets release serotonin and thromboxane A2.
_________ stimulates vascular spasms (constriction of vessels) to reduce blood pressure in damaged area. Serotonin
_________ stimulates sticking of platelets to other platelets, which release more ___________ in a positive feedback mechanism. Thromboxane A2
Production of thromboxane A2 involves action of _____________ and other enzymes in a process where __________ is converted to thromboxane A2. cyclo-oxygenase enzyme (COX); arachadonic acid (a fatty acid)
______ functions to inhibit cyclo-oxygenase and thus 81 mg. per day may reduce platelets from sticking (blood thinner) Aspirin
When a fetus enters the _____ of the _______, stretch receptors send inpulses to the ____________. Cervix of the uterus; hypothalamus.
Hypothalamus releases ______ (a hormone) by way of the ___________________ into the bloodstream. Oxytocin by way of the posterior pituitary gland
___________ goes to the uterine muscles and stimulates further contraction, pushing the fetus further into the cervix, causing additional stretching. (process repeats until birth occurs) Oxytocin
Nursing baby stimulates nipples, sending nerve impulses to the hypothalamus, which releases oxytocin again from the ____________; oxytocin stimulates ejection of milk into the nipple so it is available to the nursing infant. (Oxytocin does not cause milk production) posterior pituitary gland
_______________ released when kidneys sense hypoxia (lack of oxygen) presumably due to a lack of sufficient _________ cells in bloodstream. Erythropoietin; red blood cells
_______ stimulates ___________ ( production of red blood corpuscles from myeloid stem cells) within the bone marrow in order to bring blood cell count up to normal in this negative feed back system. Erythropoietin stimulates erythropoiesis
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