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Malignancies

Mark George 13 questions

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Questions in this quiz (13)

  1. 1Which of the following are features of cancer cells?
    1. Aautonomic & immortal
    2. Bstatic & aplastic
    3. Ctransformational & variable
    4. Danaplastic & lacking apoptosis
  2. 2Which of the following can act as tumor markers?
    1. Aproteins
    2. Bvitamins
    3. Chormones
    4. Dantibodies
    5. Eantigens
  3. 3Tumor markers can confirm diagnosis of some cancers.
    1. ATrue
    2. BFalse
  4. 4Which of the statements below is FALSE?
    1. APheochromocytoma is a tumor of the adrenal medulla.
    2. BAdrenaline can act as a tumor marker.
    3. CPSA is a tumor marker specifically for prostate cancer
    4. DTumor markers can be found in blood, urine and CSF.
  5. 5Gene mutations can result in......
    (Select the INCORRECT answer)
    1. ARepeated division of telomeres.
    2. BActivation of tumor suppression genes.
    3. CCancer cells stimulating angiogenesis
    4. DStimulation of growth promotion pathways
    5. ETransformation of proto-oncogenes into oncogenes.
  6. 6Regarding the contribution of obesity to cancer, which of the following statements are true?
    1. ABMI greater than 30 linked to cancer.
    2. BThe endocrine and metabolic activity of adipose tissue is thought to contribute to cancer development
    3. CThe increased release of FFA and TNF is thought to contribute to cancer development
    4. DIncreased levels of insulin is also linked to cancer development.
  7. 7Which of the following sets of factors all increase the risk of cancer development?
    1. ACHronic inflammation, over-exertion, poor diet and television.
    2. BViruses, bacteria, chronic inflammation and environmental factors
    3. Csmoking, radiation, alcohol and shopping
    4. DUlcerative colitis, chronic asthma, physical inactivity and Epstein Barr Virus
  8. 8Select the true statements regarding pharmacological management of cancer.
    1. ANarcotic analgesics act to inhibit the release of substance P
    2. BAdverse effects of narcotic analgesics include diarrhoea, psychological disturbances and vomiting
    3. CFentanyl is slow to act but has a long half life.
    4. DAccumulation of morphine can result in coma
    5. EBuprenorphine and azathioprine are used in the treatment of terminal cancer pain
  9. 9Select the cytotoxic agents
    1. ACalcium channel blockers
    2. BAntiarbitrucins
    3. CAntimetabolites
    4. DAlkylating agents
    5. EHormonal agonists
    6. FHormonal inhibitors
  10. 10Chlorambucil and Carboplatin target the mechanism for cell division
    1. ATrue
    2. BFalse

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Description
Pathophysiology and pharmacology of malignancies lecture
Language
English
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