985233
Description
Quiz by Mark George, updated more than 1 year ago
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Created by Mark George
over 10 years ago
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Question 1
Question
Which of the following are features of cancer cells?
Answer
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autonomic & immortal
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static & aplastic
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transformational & variable
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anaplastic & lacking apoptosis
Question 2
Question
Which of the following can act as tumor markers?
Answer
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proteins
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vitamins
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hormones
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antibodies
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antigens
Question 3
Question
Tumor markers can confirm diagnosis of some cancers.
Answer
- True
- False
Question 4
Question
Which of the statements below is FALSE?
Answer
-
Pheochromocytoma is a tumor of the adrenal medulla.
-
Adrenaline can act as a tumor marker.
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PSA is a tumor marker specifically for prostate cancer
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Tumor markers can be found in blood, urine and CSF.
Question 5
Question
Gene mutations can result in......
(Select the INCORRECT answer)
Answer
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Repeated division of telomeres.
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Activation of tumor suppression genes.
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Cancer cells stimulating angiogenesis
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Stimulation of growth promotion pathways
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Transformation of proto-oncogenes into oncogenes.
Question 6
Question
Regarding the contribution of obesity to cancer, which of the following statements are true?
Answer
-
BMI greater than 30 linked to cancer.
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The endocrine and metabolic activity of adipose tissue is thought to contribute to cancer development
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The increased release of FFA and TNF is thought to contribute to cancer development
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Increased levels of insulin is also linked to cancer development.
Question 7
Question
Which of the following sets of factors all increase the risk of cancer development?
Answer
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CHronic inflammation, over-exertion, poor diet and television.
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Viruses, bacteria, chronic inflammation and environmental factors
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smoking, radiation, alcohol and shopping
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Ulcerative colitis, chronic asthma, physical inactivity and Epstein Barr Virus
Question 8
Question
Select the true statements regarding pharmacological management of cancer.
Answer
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Narcotic analgesics act to inhibit the release of substance P
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Adverse effects of narcotic analgesics include diarrhoea, psychological disturbances and vomiting
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Fentanyl is slow to act but has a long half life.
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Accumulation of morphine can result in coma
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Buprenorphine and azathioprine are used in the treatment of terminal cancer pain
Question 9
Question
Select the cytotoxic agents
Answer
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Calcium channel blockers
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Antiarbitrucins
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Antimetabolites
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Alkylating agents
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Hormonal agonists
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Hormonal inhibitors
Question 10
Question
Chlorambucil and Carboplatin target the mechanism for cell division
Answer
- True
- False
Question 11
Question
The antiandrogenic drug Flutamide is administered to prostate cancer sufferers.
Answer
- True
- False
Question 12
Question
5-fluorouacil (5-FU) is an hormonal inhibitor that acts by blocking synthesis of pyramidine nucleotides
Answer
- True
- False
Question 13
Question
Side effects common to alkylating agents, antibiotic-type agents and antimetabolites include
Answer
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Bone marrow suppression
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GI disturbances
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mouth ulcers
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impaired fertility
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bleeding
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