PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps

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PHSI3011 01-2 Cardiac excitation-contraction coupling 1 - Channels, exchangers, pumps
Michael Jardine
Test por Michael Jardine, actualizado hace más de 1 año
Michael Jardine
Creado por Michael Jardine hace casi 7 años
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Resumen del Recurso

Pregunta 1

Pregunta
Which of the following is NOT a type of Calcium channel?
Respuesta
  • G-type
  • L-type
  • N-type
  • T-type

Pregunta 2

Pregunta
An L-type Calcium channel has how many subunits? (each controlled by a separate gene)
Respuesta
  • 2
  • 3
  • 4
  • 5
  • 6
  • 7
  • 8

Pregunta 3

Pregunta
An L-type Calcium channel is highly selective for Calcium, but is also somewhat permeable to Sodium and Potassium.
Respuesta
  • True
  • False

Pregunta 4

Pregunta
During diastole, the Na/Ca exchanger and the SR Ca pump both move Ca. Which way around?
Respuesta
  • Na/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back INTO the SR.
  • Na/Ca exchanger will pull Ca IN to the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.
  • Na/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back INTO the SR.
  • Na/Ca exchanger will push Ca OUT from the myoplasm; the SR Ca pump will pump Ca back OUT of the SR.

Pregunta 5

Pregunta
The longitudinal SR contains a high concentrations of proteins acting as an ATP-dependent Ca pump - returning Ca from the myoplasm to the SR lumen (to help terminate contraction). These proteins are called SERCA. What does SERCA stand for? [blank_start]S[blank_end] [blank_start]E[blank_end] [blank_start]R[blank_end] [blank_start]C[blank_end] [blank_start]A[blank_end]
Respuesta
  • Sarco
  • Sarcoplasmic
  • Endo
  • Endoplasmic
  • [plasmic] Reticulum
  • [plasmic] Ryanodine
  • Calcium
  • Concentration
  • Activation
  • Activator
  • Adjustment
  • ATPase

Pregunta 6

Pregunta
The role that Phospholamban plays in regulation of the SR Ca pump is:
Respuesta
  • Inhibitory; cancelled when phosphorylated.
  • Inhibitory; reinforced when phosphorylated.
  • Permissive; cancelled when phosphorylated.
  • Permissive; reinforced when phosphorylated.
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