11225064
Descripción
Test por Michael Jardine, actualizado hace más de 1 año
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Creado por Michael Jardine
hace casi 7 años
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Pregunta 1
Pregunta
Glycolysis turns [blank_start]__________[blank_end] into [blank_start]__________[blank_end].
Respuesta
-
Glucose-6-P
-
Pyruvate
-
Glucose
-
Glycogen
-
Lactate
-
Glycerol
-
Amino Acids
Pregunta 2
Pregunta
Glycogenesis turns [blank_start]__________[blank_end] into [blank_start]__________[blank_end].
Respuesta
-
Glucose-6-P
-
Pyruvate
-
Lactate
-
Glucose
-
Glycerol
-
Amino Acids
-
Glycogen
Pregunta 3
Pregunta
Gluconeogenesis turns [blank_start]__________[blank_end] into [blank_start]__________[blank_end].
Respuesta
-
Pyruvate
-
Glucose-6-P
-
Glucose
-
Glycogen
-
Glucagon
Pregunta 4
Pregunta
Glycogenolysis turns [blank_start]__________[blank_end] into [blank_start]__________[blank_end].
Respuesta
-
Glycogen
-
Glucose-6-P
-
Pyruvate
-
Glucose
-
Lactate
-
Glycerol
-
Glucagon
-
Amino Acids
Pregunta 5
Pregunta
The three rate-limiting steps of Gluconeogenesis are:
Respuesta
-
Glucose 6-Phosphatase
-
Fructose 1,6-bisphosphatase
-
PEP carboxykinase
-
Pyruvate kinase
-
Phosphofructokinase-1
-
Hexokinase
Pregunta 6
Pregunta
The three rate-limiting steps of Glycolysis are:
Respuesta
-
Glucose 6-Phosphatase
-
Fructose 1,6-bisphosphatase
-
PEP carboxykinase
-
Pyruvate kinase
-
Phosphofructokinase-1
-
Hexokinase
Pregunta 7
Pregunta
Which one is which: Glycolysis vs Gluconeogenesis
Respuesta
-
Gluconeogenesis
-
Glycolysis
Pregunta 8
Pregunta
Put the three rate-limiting steps (of each side) in the right places.
Respuesta
-
Glucose 6-Phosphatase
-
Fructose 1,6-bisphosphatase
-
PEP carboxykinase
-
Hexokinase
-
Phosphofructokinase-1
-
Pyruvate kinase
Pregunta 9
Pregunta
Does insulin STIMULATE or SUPPRESS glucose disposal and glycogen&lipid synthesis?
Respuesta
-
Stimulate
-
Suppress
Pregunta 10
Pregunta
Does insulin STIMULATE or SUPPRESS glucose production and VLDL secretion?
Respuesta
-
Stimulate
-
Suppress
Pregunta 11
Pregunta
What’s a LIRKO?
Respuesta
-
Liver-specific Insulin Receptor KnockOut mouse
-
Loss of Insulin Receptor KnockOut mouse
-
Liver-specific Insulin Receptor Knockout Organism
-
Loss of Insulin Receptor Knockout Organism
Pregunta 12
Pregunta
What results in a LIRKO in regards to blood&serum glucose levels?
Respuesta
-
Blood increase; serum increase
-
Blood increase; serum decrease
-
Blood decrease; serum increase
-
Blood decrease; serum decrease
Pregunta 13
Pregunta
Loss of PTEN expression in the liver results in increased Liver Triglyceride levels. What’s PTEN?
Respuesta
-
Phosphatase and TENsin homolog
-
Phosphatase and TENsin ligand
-
Phosphatase and TENsin binding factor
-
Phosphatase and TENsin lipase
Pregunta 14
Pregunta
Glucose is taken up in a GLUT2-dependent manner. It’s then stored as [blank_start]__________[blank_end] until blood glucose levels drop.
Respuesta
-
Glycogen
-
Glucose 6-Phosphate
-
Pyruvate
-
Glucagon
-
Glycerol
Pregunta 15
Pregunta
The liver contributes to the homeostasis of circulating levels of which?
Respuesta
-
Fatty Acids
-
Cholesterol
Pregunta 16
Pregunta
The liver is the main clearance tissue for removal of Fatty Acids from circulation, then repackages them in what?
Respuesta
-
VLDL-TAG
-
LDL-TAG
-
HDL-TAG
-
Chylomicron-TAG
Pregunta 17
Pregunta
Stages of Lipoprotein and FA uptake:
[blank_start]_____[blank_end] – [blank_start]__________[blank_end] resides on endothelial cells to hydrolyse VLDL-TAG to FAs for uptake
Respuesta
-
Stage 1
-
Stage 2
-
Stage 3
-
Hepatic lipase (and Lipoprotein lipase)
-
Periphery
-
Liver
Pregunta 18
Pregunta
Stages of Lipoprotein and FA uptake:
[blank_start]_____[blank_end] – [blank_start]__________[blank_end]: TAG-rich VLDL interacts with VLDL-R, enters lysosomal pathway for hydrolysis and TAG synthesis.
Respuesta
-
Stage 1
-
Stage 2
-
Stage 3
-
Hepatic lipase (and Lipoprotein lipase)
-
Periphery
-
Liver
Pregunta 19
Pregunta
Stages of Lipoprotein and FA uptake:
[blank_start]_____[blank_end] – [blank_start]__________[blank_end]: VLDL-remnants interact with a range of receptors for endocytosis.
Respuesta
-
Stage 1
-
Stage 2
-
Stage 3
-
Hepatic lipase (and Lipoprotein lipase)
-
Periphery
-
Liver
Pregunta 20
Pregunta
Fatty Acid metabolism. The major pathways are:
De novo lipogenesis: [blank_start]__________[blank_end]
TriAcylGlycerol metabolism: [blank_start]__________[blank_end]
β-Oxidation: [blank_start]__________[blank_end]
Respuesta
-
Synthesis of fatty acids from non-lipid
-
Esterification, Lipoprotein and Lipolysi
-
FA-CoA >> acetyl-CoA
Pregunta 21
Pregunta
Fatty Acid Metabolism: loss of Lipolysis-Stimulated Receptor (LSR) expression does what?
Respuesta
-
Increase in Serum TriGlyceride levels
-
Decrease in Liver TriGlyceride levels
-
Decrease in Serum TriGlyceride levels
-
Increase in Liver TriGlyceride levels
Pregunta 22
Pregunta
Loss of CD36 in the liver leads to [blank_start]__________[blank_end] Plasma FA levels. Plasma FAs [blank_start]__________[blank_end] LPL activity. Therefore loss of CD36 [blank_start]__________[blank_end] Chylomicron/VLDL-TAG hydrolysis (breakdown). …Leading to [blank_start]__________[blank_end] of TAG in the circulation.
Respuesta
-
Increased
-
Unaffected
-
Reduced
-
Inhibit
-
Stimulate
-
Reduces
-
Increases
-
Accumulation
-
Shortage
Pregunta 23
Pregunta
True or false: The Hepatokine ILGF stands for Insulin-Like Growth Factor.
Respuesta
- True
- False
Pregunta 24
Respuesta
-
Glycolysis
-
Glycogenesis
-
Gluconeogenesis
-
Glycogenolysis
Pregunta 25
Respuesta
-
Glycolysis
-
Glycogenesis
-
Gluconeogenesis
-
Glycogenolysis
Pregunta 26
Respuesta
-
Glycolysis
-
Glycogenesis
-
Gluconeogenesis
-
Glycogenolysis
Pregunta 27
Respuesta
-
Glycolysis
-
Glycogenesis
-
Gluconeogenesis
-
Glycogenolysis
Pregunta 28
Respuesta
-
Pyruvate
-
Glycogen
Pregunta 29
Respuesta
-
Pyruvate
-
Glycogen
Pregunta 30
Respuesta
-
Pyruvate
-
Glycogen
Pregunta 31
Respuesta
-
Pyruvate
-
Glycogen
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