PHSI3011 05-2 Maintenance of Bone Health

Descripción

PHSI3011 05-2 Maintenance of Bone Health
Michael Jardine
Test por Michael Jardine, actualizado hace más de 1 año
Michael Jardine
Creado por Michael Jardine hace casi 7 años
16
0

Resumen del Recurso

Pregunta 1

Pregunta
If Resorption < Formation:
Respuesta
  • ↑ Bone Mass
  • ↓ Bone Mass

Pregunta 2

Pregunta
Which of the following are bone mass determinants:
Respuesta
  • Genetics
  • Age
  • Mechanical loading
  • Protein intake
  • Calcium intake
  • Vitamin D
  • Sex steroids
  • Vitamin C

Pregunta 3

Pregunta
Sclerostin is released by which of the following?
Respuesta
  • Osteocytes
  • Osteoblasts
  • Osteoclasts
  • Lining Cells

Pregunta 4

Pregunta
Sclerostin __________ Wnt signalling in Osteoblasts/Osteocytes
Respuesta
  • Inhibits
  • Stimulates

Pregunta 5

Pregunta
With deformity of bone (on loading), sclerostin secretion:
Respuesta
  • Increases
  • Decreases

Pregunta 6

Pregunta
SOST = ??
Respuesta
  • SclerOSTin
  • Stimulated by OSTeocyte

Pregunta 7

Pregunta
Obligatory urine Calcium loss is [blank_start]__________[blank_end] mg/d (although [blank_start]__________[blank_end] after menopause).
Respuesta
  • 150-200
  • 1000
  • 25
  • 300
  • More
  • Less

Pregunta 8

Pregunta
Recommended daily allowance for calcium changes according to age, but broadly mostly around:
Respuesta
  • 1000
  • 70
  • 150-200
  • 700
  • 2000
  • 1500-2000
  • 25
  • 300

Pregunta 9

Pregunta
Vitamin D [blank_start]__________[blank_end] gut Calcium absorption:
Respuesta
  • Decreases
  • Increases

Pregunta 10

Pregunta
A non-Calcium-rich diet will usually have approximately [blank_start]__________[blank_end] mg/d Calcium. This is [blank_start]__________[blank_end]% of recommended intake.
Respuesta
  • 300
  • 1000
  • 150-200
  • 30
  • 15-20
  • 25
  • 100
  • 70

Pregunta 11

Pregunta
True or false: Exposure to the sun is [normally] our main source of Vitamin D.
Respuesta
  • True
  • False

Pregunta 12

Pregunta
True or false: Diet is [normally] our main source of Vitamin D.
Respuesta
  • True
  • False

Pregunta 13

Pregunta
What’s the recommended daily intake of Vitamin D?
Respuesta
  • 1000IU (25μg)
  • 25IU (1000μg)

Pregunta 14

Pregunta
Which of the following accelerates Vitamin D degradation?
Respuesta
  • Some medications
  • LOW Calcium intake
  • HIGH Calcium intake
  • HIGH PTH
  • LOW PTH

Pregunta 15

Pregunta
Which of the following groups are commonly associated with increased risk of Vitamin D deficiency?
Respuesta
  • Geriatric admissions to hospital
  • Dark-skinned people, especially with modest dress
  • Obese people
  • Fair skinned people with severe tan
  • Fair skinned people who avoid sun because of skin cancer risk
  • Office workers
  • Night shift workers
  • Farmers

Pregunta 16

Pregunta
In a study of 100 office workers in Sydney, sunscreen users had [blank_start]__________[blank_end] Vitamin D levels compared to non-users.
Respuesta
  • Higher
  • Lower

Pregunta 17

Pregunta
How does Vitamin D help bone health?
Respuesta
  • Increases gut Calcium absorption
  • Facilitates bone mineralisation
  • Important for muscle function
  • Permits release of bone stores of Calcium
  • It doesn’t

Pregunta 18

Pregunta
Vitamin D deficiency leads to increased bone turnover. Severe Vitamin D deficiency leads [primarily] to?
Respuesta
  • Osteomalacia
  • Osteoporosis
  • Both of the above
  • Neither of the above

Pregunta 19

Pregunta
Adequate levels of [blank_start]__________[blank_end] are needed to maximise Calcium absorption and [blank_start]__________[blank_end] ParaThyroid Hormone (PTH).
Respuesta
  • 25OHD
  • 25HD
  • 25OD
  • 2OH5D
  • 20O5HD
  • Suppress
  • Increase

Pregunta 20

Pregunta
25OHD = ??
Respuesta
  • 25(OH) vitamin D
  • 1,25(OH) vitamin D
  • 1,25(OH)2 vitamin D
  • 25(OH)2 vitamin D

Pregunta 21

Pregunta
Severe CALCIUM deficiency can lead to:
Respuesta
  • Osteoporosis
  • Osteomalacia
  • Rickets

Pregunta 22

Pregunta
Severe VITAMIN D deficiency can lead to Osteomalacia/Rickets. Are they the same thing?
Respuesta
  • Yeah
  • Nah

Pregunta 23

Pregunta
Which of the following helps to maintain normal balance between bone formation and resorption:
Respuesta
  • Androgens
  • Oestrogens
  • Both of the above
  • Neither of the above

Pregunta 24

Pregunta
True or False: Oestrogens help to keep bone cells alive.
Respuesta
  • True
  • False

Pregunta 25

Pregunta
True or False: Androgens help to keep bone cells alive.
Respuesta
  • True
  • False

Pregunta 26

Pregunta
True or false: Anorexia leads to weak bones solely through nutrient deficiency.
Respuesta
  • True
  • False

Pregunta 27

Pregunta
Glucocorticoids (Cortisone etc) are catabolic at pharmacologic doses. Where does each manifestation occur? ↓ Calcium absorption in the [blank_start]__________[blank_end]; ↑ Calcium losses in the [blank_start]__________[blank_end]; ↓ IGF-1 in the [blank_start]__________[blank_end];
Respuesta
  • Gut
  • Kidney
  • Bone

Pregunta 28

Pregunta
Protein intake helps:
Respuesta
  • Bone function
  • Muscle function
  • Both of the above
  • Neither of the above

Pregunta 29

Pregunta
If a diet contains inadequate Calcium to replace urinary losses, what happens?
Respuesta
  • Raid bones for Calcium
  • Nothing
Mostrar resumen completo Ocultar resumen completo

Similar

Epithelial tissue
Morgan Morgan
Renal System A&P
Kirsty Jayne Buckley
Physiology / Intro psychology
Molly Macgregor
Introduction to Therapeutic Physical Agents
natalia m zameri
Malignancies
Mark George
PHSI3011 05-1 Bone and Teeth - Structure & Function
Michael Jardine
PHSI3011 08-1 Hormonal control of bone (PTH and sex steroids)
Michael Jardine
PHSI3011 04-1 Regulation of Blood Vessels
Michael Jardine
PHSI3011 M2 (W3) Muscle/nerve stuff
Michael Jardine
PHSI3011 11-2 Liver in Metabolic Homeostasis
Michael Jardine
PHSI3011 08-2 Physiology of Circadian Rhythms
Michael Jardine