Bone L3

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Lecture 3: Disorders
Melissa Thomas
Fichas por Melissa Thomas, actualizado hace más de 1 año
Melissa Thomas
Creado por Melissa Thomas hace más de 5 años
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Pregunta Respuesta
"Congenital malformations AKA .... is the developmental irregularities caused by localised problems in migration of the mesenchymal cells and the formation of the condensations." Dystoses
This type of one abnormality results from mutations in certain transcription factors known as ... genes. Homeobox genes.
"..... are mutations in the regulators of skeletal organogenesis that affects cartilage and bone tissues." Dysplasias.
Regulators of skeletal oranogenesis include ...(name 2) Signalling molecules (grow factors and their receptors) and matrix components (type 1 & 2 collagen).
Distress are relatively uncommon. Name 3 examples. Failure of a bone to develop, formation of extra bones or the fusion of 2 adjacent digits (syndactylism).
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