Glucose- F.A Cycle

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(Metabolic States) Year 2 Fichas sobre Glucose- F.A Cycle, creado por gina_evans0312 el 04/03/2014.
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Role of Glucose- F.A cycle High F.A's in the bloodstream= low glucose, so glycolysis must be switched off
1) Mobilising of F.A's... into the bloodstream
2) Taken up into muscle and Beta oxidised ... In mitochondria, converting them to Acetly CoA
3) High Acetyl CoA inhibits Pyruvate dehydrogenase
4) Excess Acetyl CoA is converted into... citrate using oxaloacetate
5) High citrate inhibits Phosphofructokinase 1, switching off glycolysis
6) Glucose-6-phosphate builds up... inhibiting hexakinase
7) Inhibition of hexokinase Leads to inhibition of glucose phosphorylation
8) Glucose conc. increases Less enters the muscle cell, helping blood levels even
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