Renal Concentrating mech review

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Clinical Pathology Mind Map on Renal Concentrating mech review, created by karahm on 29/03/2014.
karahm
Mind Map by karahm, updated more than 1 year ago
karahm
Created by karahm over 10 years ago
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Resource summary

Renal Concentrating mech review
  1. Proximal Convoluted Tubule
    1. over 65% of filtrate is reabsorbed here (most of the Na, Cl and other anions passively follow), water passively follows Na; responsible for reabsorbing all of the filtered glucose, amino acids, proteins, ketones, and vitamins
    2. Descending Loop of Henle
      1. large amts of water are passively reabsorbed b/c of high medullary concentration gradient
      2. Ascending Loop of Henle and Early Distal Tubule
        1. IMPERMEABLE to water, Cl is actively reabsorbed, Na passively follows
        2. Late Distal Convoluted Tubules and Collecting Duct
          1. highly dependent on presence (or absence) of ADH and Aldosterone
            1. ADH is released due to increased plasma osmolality when not drinking OR decreased decreased circulating blood volume
              1. Aldosterone in a dehydrated animal causes active reabsorption of Na and secretion of K
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