Criado por gina_evans0312
aproximadamente 11 anos atrás
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Questão | Responda |
How large are they? | 402-407 amino acids long |
How many membrane spanning loops are there? | 7 |
Which terminus tends to be glycosylated? | The N-Terminus |
Is the c-terminus internal or external? | Internal |
Internal loop 3 & C terminal domain contain... | Serine & threonine for phosphorylation |
How many types of serpentine receptor are there? | 100 |
Where does the hormone bind in beta adrenergic receptors? | Below the surface, in the membrane |
Where is adrenaline formed? | In the Chromaffin cells |
What causes the release of adrenaline? | Stress or low blood sugar |
Which of the following is inhibitory in skeletal muscle? | Alpha 2 receptors |
In adrenaline production, Phenylalanine is converted to --> | Tyrosine |
Tyrosine is then converted to --> | DOPA |
DOPA is converted to Dopamine, which is then converted to --> | Adrenaline |
Which G protein is effected by the alpha 1 receptor? | GQ G-Protein |
What membrane bound enzyme does the Gq protein activate? | Phospholipase C-beta |
Phosphlipase C-beta splits Phosphatidanolsitol 4,5 bisphosphate --> | IP3 and diacylglycerol |
IP3 causes the release of ... | Calcium from the ER |
The diacylglycerol (and the inorganic ion released by IP3) activates... | Protein Kinase C |
The ion released by the IP3 also activates... | Calcium dependent kinases i.e. Phosphorylase B Kinase |
Protein Kinase C and other Ca dependent kinases phosphorylate which residues? | Serine and Threonine |
What is different between protein kinase C & the Ca dependent kinases? | They phosphorylate at different sites to each other (and cAMP dependent kinases) |
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