The SCN is [primarily?] responsible for heaps of the Circadian Rhythm stuff. What is it?
Responda
Sagittal Central Nucleus
SupraCentral Nucleus
Sagittal Cortical Nucleus
SupraCortical Nucleus
SupraChiasmal Nucleus
Sagittal Chiasmal Nucleus
Questão 2
Questão
The CLOCK and BMAL1 genes are downregulated through negative feedback from which of the following?
Responda
PER
CRY
RORa
CCGs
Questão 3
Questão
Deepest sleep [normally] occurs at what time?
Responda
12am
1am
2am
3am
4am
4:30am
6am
6:30am
Questão 4
Questão
Jet lag results in a desynchrony between the sleep-wake cycle and the Melatonin rhythm on:
Responda
Blood transcriptome
Plasma transcriptome
Renal transcriptome
Mitochondrial transcriptome
Questão 5
Questão
Human circadian rhythm disorders that maintain a stable entrainment in relation to the 24-hour day-night cycle include:
Responda
Delayed Sleep Phase Disorder (DSPD)
Advanced Sleep Phase Disorder (ASPD)
Non-24-Hour Sleep-Wake Syndrome
Irregular Sleep-Wake Rhythm (ISWR)
Shift Work Sleep Syndrome
Time Zone Change Syndrome
Free-Running Disorder (FRD)
Questão 6
Questão
Free-Running Disorder (FRD) is:
Responda
A progressive pattern of 1- to 2- hour delays in sleep onset and wake times
Temporally disorganised and variable episodes of sleeping and waking behaviour with short sleep periods of a few hours that are distributed randomly through the day and night
Somnambulism
Sleepwalking
Questão 7
Questão
The endogenous cycle is how many hours?
Responda
23
24
25
Questão 8
Questão
Mutations in CLOCK or PER3 can result in Delayed Sleep Phase Disorder (DSPD). This has been associated with metabolic & psychiatric disorders (e.g. depression, schizophrenia), but is also associated with which of the following:
Responda
Extreme eveningness preference
Extreme morningness preference
Questão 9
Questão
Treatments of human circadian rhythm disorders include:
Responda
Timed melatonin administration
Phase resetting – bright light administration
Melatonin agonists
Toughening the fuck up
Questão 10
Questão
Disruption of circadian rhythms can lead to:
Responda
Metabolic Imbalance
Disruption in melatonin levels
Disruption in blood glucose levels
Insulin resistance
Crankiness
Questão 11
Questão
True or false: Circadian rhythm disruptions have been linked to cancer.
Responda
True
False
...true AND false.
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