27225662
Descrição
Quiz por Bryan Suringa, atualizado more than 1 year ago
|
Criado por Bryan Suringa
aproximadamente 4 anos atrás
|
|
Questão 1
Questão
What two enzymes are used to bypass the pyruvate kinase reaction of glycolysis?
I. pyruvate carboxylase
II. PEP carboxykinase (PEPCK)
III. Fructose bisphosphatase
IV. Glucose-6-phosphate
Responda
-
A. I & II
-
III & IV
-
II & IV
-
II & III
Questão 2
Questão
Which of the following includes the main goals of Pentose Phosphate Pathway?
I. produce ribose-5-phosphate for nucleotide synthesis
II. produce NADPH and NADP for oxidoreductive biochemical synthesis
III. to interconvert pentoses and hexoses
Responda
-
I & II
-
II & III
-
I & III
-
I, II & III
Questão 3
Questão
Which of the following statements is/are true regarding the secondary structure of nucleic acids?
I. Guanine forms base pairs with cytosine via 2 hydrogen bonds
II. The B form of the DNA is the most common in biological systems
III. The breaking of H-bonds caused by high temperature is called melting
Responda
-
I,II & III
-
I & II
-
II & III
-
I & III
Questão 4
Questão
The phospholipid, phosphatidylinositol 4,5-bisphosphate forms the potent secondary messengers inositol triphosphate & diacylglycerol via what enzyme?
Responda
-
Phospholipase A
-
Phospholipase C
-
Phospholipase D
-
Phospholipase B
Questão 5
Questão
Which of the following is not true regarding the four enzyme complexes of the electron transport chain?
Responda
-
Complex I is known as the NADH-CoQ Oxidoreductases
-
Complex II is known as Succinate-CoQ Oxidoreductases
-
Complex III is known as Cytochrome Oxidase
-
Complex IV is known as Cytochrome Oxidase
Questão 6
Questão
Glucose and mannose are epimers at:
Responda
-
Carbon 4
-
Carbon 2
-
Carbon 3
-
Carbon 5
Questão 7
Questão
One important endogenous molecule for synthetic biotransformation of xenobiotics is glucuronic acid. It is actually the most dominant conjugative biotransformation pathway due to the readily available source of glucose. It is produce from glucose via:
Responda
-
Oxidation at carbon 1
-
Oxidation at carbon 2
-
Oxidation at carbon 6
-
Oxidation at carbon 1 & 6
Questão 8
Questão
Which of the following is not true about protein structure determination?
Responda
-
NMR is the only means of determining protein structure
-
Protein are difficult to crystallize, a disadvantage of x-ray crystallography
-
An advantage of the use of the NMR is that proteins analyzed are in their natural state
-
Large and very complex proteins can only be analyzed by x-ray crystallography
Questão 9
Questão
Tertiary structures of proteins are primarily stabilized by
I. H-bonds
II. Hydrophobic interactions
III. Ionic bonds
IV. Disulfide bonds
Responda
-
I, II, III & IV
-
I, II& IV
-
I,III & IV
-
I & III
Questão 10
Questão
In an uncompetitive inhibition of enzymatic action :
Responda
-
Inhibitor binds either to the free enzyme or the enzyme substrate complex
-
Lineweaver-Burk plots of the enzyme alone (control) & the enzyme + inhibitor are parallel to each other
-
The apparent Km is raised
-
The Vmax is unaffected
Questão 11
Questão
Which biomolecule is not considered a biopolymer?
Responda
-
Proteins
-
Lipids
-
Nucleic acids
-
Carbohydrates
Questão 12
Questão
It is regarded as the universal biological energy currency
Responda
-
Adenosine triphosphate
-
Guanosine triphosphate
-
Uncouplers
-
Calories
Questão 13
Questão
This is the final electron acceptor of the electron transport chain in aerobic respiration.
Responda
-
Complex I
-
Complex I&II
-
Nitrate
-
Oxygen
Questão 14
Questão
The most accepted hypothesis regarding oxidative phosphorylation is
Responda
-
Chemical coupling
-
Conformational coupling
-
Chemiosmotic hypothesis
-
Lock and Key Theory
Questão 15
Questão
This is a quantitative study of the energy transformations in the living cell
Responda
-
Bioenergetics
-
Thermodynamics
-
Proteomics
-
Metabolomics
Questão 16
Questão
Which of the following hormones promotes rapid glycogenolysis in both liver and muscle
Responda
-
ACTH
-
Glutamine
-
Epinephrine
-
Prolactin
Questão 17
Questão
Which vitamin can be used in the management of hyperlipidemia?
Responda
-
Thiamine
-
Riboflavin
-
Niacin
-
Pantothenic acid
Questão 18
Questão
Bond between 2 amino acids
Responda
-
Glycosidic bond
-
N-glycosyl linkage
-
Peptide Bond
-
Hydrogen bond
Questão 19
Questão
Beta oxidation of fatty acids in eukaryotic cells occurs in the
Responda
-
Cytosol
-
Mitochondria
-
Endoplasmic reticulum
-
Ribosomes
Questão 20
Questão
The pentose phosphate pathway (aka HMP Shunt) occurs in the ________ of the liver, muscle and kidney.
Responda
-
cytosol
-
mitochondria
-
endoplasmic reticulum
-
ribosomes
Questão 21
Questão
The isoelectric point is the
Responda
-
pH where the alpha amino acid exist in its negatively charged form
-
pH wherein the amino acid exist in zwitterionic form
-
Temperature at which the amino acid denatures
-
Pressure at which the amino acid hydrolyzes
Questão 22
Questão
This is the only optically inactive amino acid
Responda
-
methionine
-
Lysine
-
Citrulline
-
glycine
Questão 23
Questão
This level of protein structure is applicable only to those have several subunits
Responda
-
Primary
-
Secondary
-
Tertiary
-
Quaternary
Questão 24
Questão
Arginine is the only metabolite of the urea cycle that does not accumulate because
Responda
-
It is readily excreted
-
It is used up by the body for protein synthesis
-
There is no known deficiency in the enzyme that catabolizes it
-
It can be acquired from food
Questão 25
Questão
This is the genetic condition characterized by deficiency of the enzyme branched chain alpha-keto acid dehydrogenase
Responda
-
Maple syrup disease
-
Hartnup disease
-
Kwashiorkor
-
Marasmus
Questão 26
Questão
These are compounds related to cerebrosides that contain sphingosine, long chain fatty acids, hexoses (usually galactose or glucose) and neuraminic acid
Responda
-
cephalins
-
gangliosides
-
cytolipins
-
lecithins
Questão 27
Questão
This enzyme catalyzes the conversion fructose-6-P to fructose-1,6-bis-P
Responda
-
hexokinase
-
pyruvate kinase
-
PFK-1
-
Fructose bisphosphatase
Questão 28
Questão
Which of the following is called transamination?
Responda
-
Conversion of amino acids to hydroxyl groups
-
Conversion of amino acids to keto acids
-
Loss of ammonia from amino acids
-
Formation of ammonium salts from ammonia
Questão 29
Questão
The sugar involved in the DNA
Responda
-
ribose
-
pentose
-
deoxyribose
-
xylose
Questão 30
Questão
This is the reason why blood AB is considered as the universal recipient.
Responda
-
It is the most common among the ABO blood types
-
Blood type AB has neither A nor B substances
-
Blood type AB has no anti-A or anti-B antibodies
-
All of the above
Questão 31
Questão
Which one is true regarding the structures of lipids?
Responda
-
Eicosapentaenoic acid is a saturated fatty acid
-
They may exist as esters of cholesterol when they are enclosed in very low density
-
Linoleic acid is an omega-3 fatty acid
-
Capric acid contains 12 carbons
Questão 32
Questão
This is the product of basic hydrolysis of fats and oils
Responda
-
fatty acid
-
triacylglycerol
-
soap
-
detergent
Questão 33
Questão
The group of lipids that is considered amphipathic
Responda
-
sterols
-
fatty acids
-
trans-fatty acids
-
phospholipids
Questão 34
Questão
Which properly describes a liposome?
Responda
-
It is a hollow sphere-like structure composed of a lipid bilayer enclosing an aqueous cavity
-
It is a lipid structure wherein the hydrophobic chains of the fatty acids are sequestered at the core of the sphere with virtually no water in the hydrophobic interior
-
It is a lipoprotein integrated in the phospholipid bilayer of the cell membranes
-
It is a hollow sphere-like structure composed of a lipid monolayer enclosing a hydrophobic cavity
Questão 35
Questão
It is the building block of essential fatty acids
Responda
-
Malonyl CoA
-
Phosphoribosyl pyrophosphate
-
Acetyl CoA
-
HMG CoA
Questão 36
Questão
The digestion of carbohydrates begins in the________.
Responda
-
mouth
-
stomach
-
small intestine
-
duodenum
Questão 37
Questão
Cellular elements of the blood devoid of nucleus
Responda
-
RBC
-
WBC
-
thrombocytes
-
all of the above
Questão 38
Questão
Conjugated proteins which are a combination of amino acids and carbohydrates
Responda
-
nucleoproteins
-
glycoproteins
-
phosphoproteins
-
chromoproteins
Questão 39
Questão
Glucose is normally absent in the urine because kidneys normally completely reabsorb all glucose. Which of the following is true?
Responda
-
Glucosuria confirms diabetes mellitus
-
Glucosuria necessarily means hyperglycemia
-
Glucosuria is solely attributed to insulin problem
-
Glucosuria may occur in other disease states
Questão 40
Questão
Wernicke-Korsakoff syndrome which can cause acute confusion, ataxia and ophthalmoplegia, can be treated with which of the following?
Responda
-
riboflavin
-
ascorbic acid
-
thiamine
-
pantothenic acid
Questão 41
Questão
This is the major excretory product of purine nucleotides
Responda
-
inosine monophosphate
-
uric acid
-
methylmalonyl CoA
-
tetrahydrofolate
Questão 42
Questão
This is the phenomena of renaturation of nucleic acid after it has been subjected to high temperature and then to room temperature
Responda
-
Hydrolysis
-
Polymerase chain reaction
-
annealing
-
hybridization
Questão 43
Questão
This is the base sequence for the start codon
Responda
-
UAG
-
UGA
-
AUG
-
UAA
Questão 44
Questão
This feature of bacterial cells confers selectivity of antibacterial agents targeting protein synthesis to the bacteria and not to the host cell.
Responda
-
mRNA
-
40s ribosomal subunit
-
lack of cell wall
-
30s ribosomal subunit
Questão 45
Questão
This is also known as the RNA-directed DNA polymerase
Responda
-
RNA polymerase II
-
Reverse transcriptase
-
DNA polymerase alpha
-
DNA polymerase II
Questão 46
Questão
What essential amino acid is used in the synthesis of niacin?
Responda
-
Tyrosine
-
Methionine
-
tryptophan
-
Phenylalanine
Questão 47
Questão
The cellular particles are often referred to by their sedimentation coefficient value, for example 70s ribosomes that are expressed in terms of 10 -13 seconds. The abbreviation “s” stands for
Responda
-
subunit
-
Seconds
-
Svedberg
-
None of the above
Questão 48
Questão
The best known building blocks of RNA and DNA are
Responda
-
purines
-
pyrimidines
-
fatty acids
-
a and b
Questão 49
Questão
The following are pathological constituents of urine, except:
Responda
-
glucose
-
albumin
-
creatinine
-
blood
Questão 50
Questão
Glucose and galactose differ only in the configuration of their hydroxyl group at carbon 4. Glucose and galactose are:
Responda
-
diastereomers
-
enantiomers
-
epimers
-
anomers
Questão 51
Questão
The chemical representation shows the most stable conformation of hexoaldopyranoses
Responda
-
Fischer projection
-
Boat conformation
-
Haworth Formula
-
Chair conformation
Questão 52
Questão
These are vegetables or animal drugs that consist of natural substances that have undergone only the process of collection and drying
Responda
-
natural substances
-
crude drugs
-
Extractives
-
Derivatives
Questão 53
Questão
What do you call plants growing in their native countries?
Responda
-
indigenous
-
naturalized
-
cultivated
-
local
Questão 54
Questão
What is used to treat cascara sagrada extract to reduce its bitter taste?
Responda
-
Magnesium oxide
-
Calcium carbonate
-
Simple syrup
-
Talc
Questão 55
Questão
What type of saponin glycosides are derivatives of steroids with spiroketal side chains?
Responda
-
Acid saponins
-
Alkaline saponins
-
Neutral saponins
-
None of the above
Questão 56
Questão
This is the final step in the preparation of drugs for the commercial market, consisting of the removal of extraneous matter.
Responda
-
Packaging
-
Preservation
-
Garbling
-
Harvesting
Questão 57
Questão
Natural relationship existing among plants and among animals
Responda
-
taxonomy
-
morphology
-
phylogeny
-
Systematics
Questão 58
Questão
8. In the preservation of crude drugs, this method is the simplest in preventing insect attacks and other form of destruction
Responda
-
Exposure of the drug to a temperature of 65°C
-
Use of methyl chloride
-
adding a few drops of benzene
-
AOTA
Questão 59
Questão
This refers to the evaluation by means of the sense organs and includes the macroscopic appearance of the drug, odor, taste, sound upon fracture and feel to the touch
Responda
-
Physical Analysis
-
Chemical Analysis
-
Proximate Analysis
-
Organoleptic Analysis
Questão 60
Questão
The first commercial application of the technique in pharmaco-biotechnology was made by Eli Lilly Company. Using the non-disease producing strain of E.coli, this company produced the hormone
Responda
-
Glucagon
-
somatostatin
-
insulin
-
somatomedin
Questão 61
Questão
Which of the following may influence the secondary constituents of plant drugs?
Responda
-
genetic composition
-
ontogeny
-
environment
-
all of the above
Questão 62
Questão
These are products of natural origin many of which without therapeutic effect used by the laity in the self-treatment of diseases.
Responda
-
Health Foods
-
Crude drugs
-
Extracts
-
AOTA
Questão 63
Questão
Which of the following statement/s is/are true?
I. Gums and mucilages are carbohydrates
II. Streptomycin is a carbohydrate
III. The concentration of secondary metabolites increases with age
IV. Biogenesis refers to the study of biochemical pathways leading to the formation of secondary constituents used as drugs
Responda
-
I, II and IV
-
I, II and III
-
I and III
-
III Only
Questão 64
Questão
Which of the following pairs is correct?
Responda
-
reserpine-hypotensive
-
sambong-stomachic
-
bayabas-diuretic
-
lagundi-analgesic
Questão 65
Questão
Which of the following statements is/are correct?
Responda
-
Synthetic Camphor is levorotatory
-
Natural Camphor is dextrorotatory
-
Both natural and semisynthetic camphor are racemic
-
NOTA
Questão 66
Questão
Give the proper sequence of the following processes in the preparation of natural drugs.
I. Garbling
II. Collection
III. Drying
IV. Harvesting
V. Packaging
Responda
-
III-I-IV-II-V
-
II-IV-III-I-V
-
II-I-IV-V-III
-
IV-I-III-V-II
Questão 67
Questão
This classification of drugs considers the natural relationship or phylogeny among plants and animals.
Responda
-
taxonomic
-
morphologic
-
zoologic
-
zoologic and taxonomic
Questão 68
Questão
The source of bassorin
Responda
-
acacia
-
Karaya
-
gum
-
Tragacanth
Questão 69
Questão
Mannitol is used pharmacologically as a/an
Responda
-
humectant
-
osmotic diuretic
-
anti-infective
-
urologic irritant
Questão 70
Questão
Which of the following is/are homoglycan(s)?
Responda
-
starch
-
starch and inulin
-
inulin
-
gums
Questão 71
Questão
The milk left after separation of the cream
Responda
-
cheese
-
condensed milk
-
skimmed milk
-
buttermilk
Questão 72
Questão
Fermentation product from molasses
Responda
-
wine
-
whiskey
-
rum
-
brandy
Questão 73
Questão
It is also known as the carob pulp or St. John's Bread
Responda
-
locust bean
-
Xanthan
-
guar
-
acacia
Questão 74
Questão
It tastes approximately half as sweet as sucrose, and has humectant properties which makes it a useful ingredient in toothpastes, chewing gums, and dietetic products.
Responda
-
mannitol
-
fructose
-
dulcitol
-
sorbitol
Questão 75
Questão
A pharmaceutical aid in the preparation of collodion and flexible collodion.
Responda
-
methylcellulose phthalate
-
soluble guncotton
-
powdered cellulose
-
cellulose acetate
Questão 76
Questão
Gum usually used as a substitute for acacia
Responda
-
ghatti
-
tragacanth
-
karaya
-
algin
Questão 77
Questão
It is also referred to as Japanese Isinglass, and is extensively used as a gel in bacteriologic culture media.
Responda
-
carrageenan
-
agar
-
chondrus
-
cydonium
Questão 78
Questão
Powdered cellulose is the purified, mechanically disintegrated cellulose used as a self-binding tablet diluent and disintegrating agent. Which of the following statements regarding powdered cellulose is correct?
A) The purity of cellulose is defined by its solubility in hydrochloric acid.
B) The cellulose remaining insoluble is termed a-cellulose.
C) The greater the quantity of a-cellulose present, the higher the quality of the material.
Responda
-
B and C only
-
A and B only
-
B only
-
NOTA
Questão 79
Questão
The most important monosaccharides found in plants
Responda
-
hexoses
-
pentoses
-
heptoses
-
octoses
Questão 80
Questão
Which of the following is a source of sucrose?
Responda
-
Acer saccharum
-
Bos taurus
-
Prunus cerasus
-
Sorbus aucuparia
Questão 81
Questão
Which of the following statements is/are true?
Responda
-
Dextrose is a-(L)-glucopyranose
-
Dextrose is obtained from controlled enzymatic hydrolysis of starch
-
Dextrose can only be given PO and IV
-
AOTA
Questão 82
Questão
This is a product obtained from the incomplete hydrolysis of starch. It is a colorless or yellowish, thick syrupy liquid that is nearly odorless and tastes sweet.
Responda
-
liquid dextrose
-
liquid sucrose
-
liquid dextrin
-
liquid glucose
Questão 83
Questão
Which of the following pairs is correct?
Responda
-
Ferrous gluconate - hematinic
-
Xylose-laxative
-
Lactulose-diagnostic aid
-
AOTA
Questão 84
Questão
Which of the following statements refers to fructose?
A) from honey
B) obtained from the inversion of aqueous solutions of sucrose
C) upon hydrolysis, sucrose yields a higher fructose than dextrose content
Responda
-
A and B only
-
B and C only
-
C only
-
B only
Questão 85
Questão
In milk processing, the liquid separated from coagulum is known as
Responda
-
condensed milk
-
butter
-
buttermilk
-
whey
Questão 86
Questão
This is a pentose also known as wood sugar, which is obtained by boiling corn cobs, straw, or similar materials with dilute acid to hydrolyze the polymer.
Responda
-
ribose
-
xylose
-
erythrose
-
trehalose
Questão 87
Questão
Which of the following statements concerning lactulose is true?
Responda
-
Natural sugar prepared by acidic rearrangement of lactose
-
Trisaccharide
-
Well absorbed
-
Bacteria in the colon metabolize it to acetic acid and lactic acid
Questão 88
Questão
Xylose is used as a /an
Responda
-
diuretic
-
pharmaceutical excipient
-
binder
-
diagnostic aid
Questão 89
Questão
In glycolysis, what enzyme is involved in the conversion of 3 phosphoglyceraldehyde to 1,3-Bisphosphoglyceric acid?
Responda
-
kinase
-
aldolase
-
dehydrogenase
-
isomerase
Questão 90
Questão
Aside from thiamine pyrophosphate, what coenzyme/cofactor aids in the oxidative decarboxylation of pyruvic acid with pyruvic acid dehydrogenase?
Responda
-
NAD
-
Lipoic Acid
-
FAD
-
Mg
Questão 91
Questão
Glucose-6-PO, is converted to ____ upon the action of phosphohexose isomerase.
Responda
-
Glucose-1-Phosphate
-
Fructose-6-Phosphate
-
Fructose-1.6-Diphosphate
-
Dihydroxyacetone phosphate
Questão 92
Questão
Pyruvic acid, upon the action of pyruvic acid decarboxylase yields ____
Responda
-
ethanol
-
lactic acid
-
methanol
-
acetaldehyde
Questão 93
Questão
Alcohol dehydrogenase acts on acetaldehyde to yield ____
Responda
-
lactic acid
-
pyruvic acid
-
ethanol
-
AOTA
Questão 94
Questão
Which tricarboxylic acid was first isolated by scheele in 1784
Responda
-
citric acid
-
Tartaric acid
-
lactic acid
-
fumaric acid
Questão 95
Questão
This acid is a byproduct of wine
Responda
-
citric acid
-
tartaric acid
-
lactic acid
-
fumaric acid
Questão 96
Questão
This acid used as an acidulant especially in feeding formulas
Responda
-
Citric acid
-
tartaric acid
-
lactic acid
-
fumaric acid
Questão 97
Questão
Which of the following may be produced from the process of distillation?
Responda
-
whiskey
-
rum
-
brandy
-
AOTA
Questão 98
Questão
Which of the following statement/s is/are true?
Responda
-
Wine is sometimes used medically as a mild stimulant and tonic
-
Brandy is used as CNS stimulant
-
Whiskey is used as CNS stimulant
-
AOTA
Questão 99
Questão
Which of the following is obtained from Fraxinus ornus I. (Fam. Oleaceae), and is used for its laxative properties?
Responda
-
glucitol
-
mannitol
-
Sorbitol
-
Lactose
Questão 100
Questão
What is the usual diagnostic dose of mannitol injection?
Responda
-
200 mg/kg body weight in a 15-25% solution IV in 3-5 minutes
-
50-100g daily in a 5-25% solution by IV infusion
-
200 g/kg body weight in a 15-25% solution in 3-5 minutes
-
50-100 kg daily in a 5-25% solution by IV infusion
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