Tyrosine Kinase

Descrição

Year 2 Quiz sobre Tyrosine Kinase, criado por gina_evans0312 em 02-12-2013.
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Quiz por gina_evans0312, atualizado more than 1 year ago
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Criado por gina_evans0312 aproximadamente 11 anos atrás
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Resumo de Recurso

Questão 1

Questão
When the ligand has bound, what moleucle forms?
Responda
  • A homodimer
  • A heterodimer within the T.K family
  • A heterotrimer within the T.K family
  • A homotrimer

Questão 2

Questão
What is found in the active site that inhibits activity?
Responda
  • A pseudosubstrate
  • An activation lip
  • A hydrophobic core that must be exposed

Questão 3

Questão
How do you activate the active site?
Responda
  • Phosphorylation
  • Acetylation
  • Methylation

Questão 4

Questão
Which residues of tyrosine kinase are modified?
Responda
  • Tyrosine
  • Serine
  • Threonine

Questão 5

Questão
What domain is required to bind to an activated Tyrosine Kinase?
Responda
  • Sh2
  • Sh4
  • SH3

Questão 6

Questão
How large is an SH2 domain?
Responda
  • 100 residues
  • 50 residues
  • 25 residues

Questão 7

Questão
How many pockets are there in SH2?
Responda
  • 1
  • 2
  • 3

Questão 8

Questão
How does a specific molecule know where to dock on a tyrosine kinase receptor?
Responda
  • The sequence of aa around the modification it binds to
  • The shape of the protein around the modification it binds to

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