Human body is controlled by two major systems:
1) Nervous system
2) Endocrine system
These systems are linked together by the hypothalamus
Reflex arc is an instant uncontrolled action:
sensory neurone > relay neurone > motor neurone
Postural reflex, e.g. knee jerk, maintains position and body control without conscious adjustment
Glial cells
Packed between neurones to form neuroglia tissue:
a) provides mechanical support and electrical insulation
b) Schwann cells are specialised glial cells, forming myelin sheaths
c) control nutrient and ionic balance. Break down neurotransmitters
Nissl tissues
Contained in neurones:
a) generate enzymes involved in impulse transmission and synthesis of trophic factors
b) regulate growth and differentiation of nervous tissue
When impulse is not transmitted: - charge (resting potential) across axon membrane = -70mV
When impulse is transmitted: - action potential is a brief reversal of resting potential
All-or-None rule: - stimulus needs the minimum intensity to initiate an action potential. Below this, there is no impulse
Impulse takes place over: - temporal or spatial summation
Rubrica: : Image of a Nissl-stained histological section (showing various classes of cells (neurons and glia)
Slide 4
Nervous Coordination (III)
Synapses are gaps between neurones to control impulses chemically. They release neurotransmitters that diffuse across synaptic cleft and trigger action potential in membrane
Once it reaches post-synaptic neurone, enzymes break it down and it diffuses back across synapse
Neurotransmitters used in the human body are:
acetylcholine (motor neurones)
noradrenaline (sympathetic synapses)
serotonin, dopamine (in brain)
Synapses: - are effected by drugs: Hallucinogens (LSD) mimic actions of other neurotransmitters Nicotine is addictiveCurare and atropine block acetylcholine
Muscarine mimics acetylcholine
Light entering eye: focused on retina - cornea does most refraction. Cornea and vitreous humour have the same refractive index- lens fine focuses using ciliary muscles: Distant object: ciliary muscles relax, ligaments tighten > lens becomes flat and thin
Close-up object: ciliary muscles contract, ligaments relax > lens becomes more spherical and fat
Iris controls pupil size:
Dim light: radial muscles contract, circular muscles relax > pupil dilates
Bright light: radial muscles relax, circular muscles contract > pupil constricts
Rods respond to dim light, responsible for peripheral vision. Contain the visual pigment, rhodopsin
Cones respond to bright light, responsible for central and colour vision. Contain the visual pigment, iodopsinRods – low visual acuityCones – high visual acuity Trichromatic theory = red, blue and green cones. Each detects different wavelength of light
Slide 7
Central Nervous System
Central Nervous System : Spinal Cord, Hindbrain, Midbrain, ForebrainCerebral Cortex: Sensory areas, Motor areas, Association areasVisual Cortex: Simple cells, Complex cells, Association areasBrain and spinal cord protected by:- Bone (skull and vertebral column)- Spinal and cranial meninges- Cerebrospinal fluid
Opposing functions of sympathetic & parasympathetic divisions of the ANS:- Iris- Ciliary muscle- Lacrimal gland- Urinary bladder wall